Overweight
Overweight is characterized as having a body mass index (BMI) of 25 to 29.9. Having overweight is associated with increased risk of conditions such as cardiovascular disease. However, this may not be the case in people with increased lean mass (e.g., athletes or weight lifters).
Quick Answer
What it is
Overweight is characterized as having a body mass index (BMI) of 25 to 29.9. Having overweight is associated with increased risk of conditions such as cardiovascular disease.
Key findings
- Grade B: Blood glucose (Resistant Starch)
- Grade B: Blood Pressure (Alpha-Linolenic Acid (ALA))
- Grade B: C-Reactive Protein (CRP) (Inulin)
Safety
- Having overweight is associated with increased risk of conditions such as cardiovascular disease.
ℹ️ Quick Facts
Quick Facts: Overweight
- Supplements Studied:43
- Research Trials:84
- Total Participants:94,012
- Top Supplement:Astaxanthin (B)
84 trials
94,012 participantsppts
43 supps · 379 outcomes
Evidence-Based Protocol
Supplement stack ranked by research quality
Primary Stack (Tier 1)
3-5g daily (1g before each main meal with water)
Soluble fiber increases satiety through gastric distension, delays gastric emptying, and reduces calorie absorption
14 studies | 900 participants
20-40g daily (1.2-1.6g/kg total protein intake)
High thermic effect, increases satiety hormones (PYY, GLP-1), and preserves lean mass during caloric deficit
30 studies | 2,000 participants
Supporting Stack (Tier 2)
250-500mg EGCG daily
Catechins inhibit COMT, prolonging norepinephrine-induced thermogenesis and fat oxidation
20 studies | 1,500 participants
10-50 billion CFU daily (Lactobacillus strains)
Modulate gut microbiome composition affecting energy harvest, appetite hormones, and metabolic inflammation
15 studies | 1,000 participants
3-6g daily
Reduces adipocyte lipid uptake and promotes lipolysis via PPAR-gamma modulation
18 studies | 1,000 participants
200-1000mcg daily
Enhances insulin sensitivity and may reduce carbohydrate cravings
12 studies | 700 participants
How It Works
Being overweight (BMI 25-29.9) increases risk of developing type 2 diabetes, heart disease, and other health conditions. Weight management requires creating a caloric deficit while maintaining nutrition and preventing muscle loss. These supplements support weight loss by increasing satiety, boosting metabolism, and optimizing body composition.
•Fiber (Glucomannan/Psyllium) is one of the most evidence-based weight loss supplements. These soluble fibers absorb water and expand in the stomach, creating a feeling of fullness that naturally reduces food intake. Glucomannan can absorb 50 times its weight in water. Studies show consistent weight loss of 2-4 lbs over 8 weeks without other dietary changes. Take 30 minutes before meals with plenty of water.
•Protein Supplementation supports weight loss through multiple mechanisms: it has the highest thermic effect of food (20-30% of calories burned during digestion), strongly increases satiety hormones, and critically preserves muscle mass during caloric restriction. Losing muscle slows your metabolism—adequate protein prevents this metabolic slowdown.
•Green Tea Extract (EGCG) modestly increases metabolic rate and fat burning by inhibiting an enzyme that breaks down norepinephrine. The combination with caffeine is synergistic. Effects are small (50-100 extra calories burned daily) but compound over time.
•Probiotics may influence body weight through the gut microbiome. Certain strains (particularly Lactobacillus gasseri and L. rhamnosus) have been shown to reduce body weight and belly fat. They may work by reducing calorie extraction from food and improving metabolic hormones.
•CLA (Conjugated Linoleic Acid) may help reduce body fat accumulation, particularly around the abdomen. Effects are modest but meaningful as part of a comprehensive approach.
•Chromium can help reduce carbohydrate cravings and improve insulin sensitivity, making it easier to stick to a reduced-calorie diet.
Expected timeline: Fiber effects on appetite are immediate. Metabolic effects from green tea begin within days. Measurable weight loss typically requires 4-8 weeks of consistent use. Best results when combined with a modest caloric deficit (250-500 kcal/day) and regular physical activity.
Generated from peer-reviewed researchSchema v2.0
Supplements for Overweight
Sorted by strength of evidence
Detailed Outcomes
Grade:
Effect:
Size:
Sort:
|
B
Blood glucose
Small Improvement
16 studies503 participants
small↓Improves
?
Insulin
15 studies503 participants
↑Worsens
?
HbA1c
4 studies503 participants
↓Improves
?
Insulin Resistance
3 studies503 participants
↓Improves
B
Blood glucose
Small Improvement
9 studies329 participants
small↓Improves
?
Body Mass Index (BMI)
25 studies1418 participants
↓Improves
?
Weight
23 studies1265 participants
↓Improves
?
Waist circumference
11 studies753 participants
↓Improves
?
Body Fat
8 studies516 participants
↓Improves
?
Insulin Resistance
7 studies191 participants
↓Improves
?
HbA1c
6 studies271 participants
↓Improves
?
Insulin
6 studies172 participants
↑Worsens
?
Intercellular Adhesion Molecule 1
1 study1034 participants
↑Worsens
?
Plasminogen Inhibitor-1
1 study1034 participants
↑Improves
?
Vascular Function
1 study1034 participants
↑Improves
B
Blood Pressure
Mixed effect on blood pressure
9 studies689 participants
?
C-Reactive Protein (CRP)
10 studies241 participants
↑Worsens
?
Total cholesterol
10 studies544 participants
↑Worsens
?
Triglycerides
9 studies505 participants
↑Worsens
?
High-density lipoprotein (HDL)
8 studies503 participants
↑Improves
?
Low-density lipoprotein (LDL)
8 studies503 participants
↑Worsens
?
TNF-Alpha
7 studies357 participants
↑Worsens
?
Interleukin 6
6 studies303 participants
↑Worsens
B
C-Reactive Protein (CRP)
Small Decrease
6 studies211 participants
small↓Improves
?
Ghrelin
3 studies109 participants
↑Improves
B
Beta-cell function
Small Decrease
3 studies82 participants
small↓Worsens
?
Insulin
3 studies82 participants
↑Worsens
?
Insulin Resistance
3 studies82 participants
↑Worsens
?
HbA1c
2 studies134 participants
↑Worsens
?
Blood glucose
1 study172 participants
↑Worsens
B
Anti-Oxidant Enzyme Profile
Moderate Increase
2 studies50 participants
moderate↑Improves
?
Oxidative Stress Biomarkers
2 studies50 participants
↑Worsens
?
Apolipoprotein A
1 study27 participants
↑Improves
?
Apolipoprotein B
1 study27 participants
↑Worsens
?
High-density lipoprotein (HDL)
1 study27 participants
↑Improves
?
Low-density lipoprotein (LDL)
1 study27 participants
↑Worsens
?
Total cholesterol
1 study27 participants
↑Worsens
?
Triglycerides
1 study27 participants
↑Worsens
?
Weight
1 study27 participants
↑Worsens
C
Body Weight
Meta-analysis: weight reduction of -1.48kg with barberry supplementation
11 studies718 participants
small↓Improves
C
Anti-Oxidant Enzyme Profile
Small Increase
1 study60 participants
small↑Improves
?
Endogenous Advanced Glycation End Products
1 study60 participants
↑Improves
?
Interleukin 6
1 study60 participants
↓Improves
?
Lipoprotein(a)
1 study60 participants
↑Improves
?
Oxidative Stress Biomarkers
1 study60 participants
↓Improves
C
Body Fat
Small Decrease
1 study92 participants
small↓Improves
?
Weight
7 studies422 participants
↓Improves
?
Waist circumference
6 studies297 participants
↓Improves
?
Visceral Fat
5 studies231 participants
↓Improves
?
Body Mass Index (BMI)
3 studies244 participants
↓Improves
?
Low-density lipoprotein (LDL)
3 studies412 participants
↓Improves
?
High-density lipoprotein (HDL)
1 study92 participants
↑Improves
?
Hip Circumference
1 study92 participants
↓Improves
?
Muscle Mass
1 study92 participants
↑Improves
?
Total cholesterol
1 study92 participants
↓Improves
?
Waist-Hip Ratio
1 study92 participants
↑Improves
C
Blood glucose
Small Improvement
1 study97 participants
small↓Improves
C
Blood Pressure
Small Improvement
1 study97 participants
small↓Improves
?
Low-density lipoprotein (LDL)
1 study97 participants
↓Improves
?
Total cholesterol
1 study97 participants
↓Improves
?
Triglycerides
1 study97 participants
↓Improves
C
Arterial Stiffness
Small Improvement
1 study40 participants
small↓Improves
?
Body Fat
3 studies109 participants
↓Improves
?
Low-density lipoprotein (LDL)
2 studies98 participants
↓Improves
?
Total cholesterol
2 studies98 participants
↓Improves
?
Triglycerides
2 studies98 participants
↓Improves
?
Waist-Hip Ratio
2 studies52 participants
↑Improves
?
Weight
2 studies60 participants
↓Improves
?
Blood Pressure
1 study40 participants
↓Improves
?
High-density lipoprotein (HDL)
1 study78 participants
↑Improves
?
Nesfatin-1
1 study20 participants
↑Improves
?
Omentin-1
1 study20 participants
↑Improves
?
Oxidative Stress Biomarkers
1 study78 participants
↓Improves
?
Total Antioxidant Capacity (TAC)
1 study78 participants
↑Improves
C
Anti-Oxidant Enzyme Profile
Small Increase
1 study30 participants
small↑Improves
?
Triglycerides
27 studies2344 participants
↓Improves
?
High-density lipoprotein (HDL)
25 studies2344 participants
↑Improves
?
Blood Pressure
18 studies2344 participants
↓Improves
?
Waist circumference
18 studies2344 participants
↓Improves
?
Blood glucose
16 studies2344 participants
↓Improves
?
Weight
3 studies2002 participants
↓Improves
?
Body Fat
2 studies1972 participants
↓Improves
?
Blood Flow
1 study20 participants
↑Improves
?
Body Mass Index (BMI)
1 study1902 participants
↓Improves
?
C-Reactive Protein (CRP)
1 study20 participants
↓Improves
?
Glycemic Control
1 study70 participants
↑Improves
?
Inflammation
1 study20 participants
↓Improves
?
Insulin
1 study70 participants
↑Worsens
?
Low-density lipoprotein (LDL)
1 study70 participants
↓Improves
?
Total cholesterol
1 study70 participants
↓Improves
C
Adiponectin
Small increase in adiponectin
1 study102 participants
small↑Improves
?
Body Fat
1 study102 participants
↑Worsens
?
C-Reactive Protein (CRP)
1 study102 participants
↑Worsens
?
High-density lipoprotein (HDL)
1 study102 participants
↑Improves
?
Leptin
1 study102 participants
↑Improves
?
Low-density lipoprotein (LDL)
1 study102 participants
↑Worsens
?
Total cholesterol
1 study102 participants
↑Worsens
?
Weight
1 study102 participants
↑Worsens
C
Blood glucose
Small Improvement
1 study155 participants
small↓Improves
?
Blood Pressure
1 study155 participants
↓Improves
?
Cortisol
1 study51 participants
↓Improves
?
Glycemic Control
1 study155 participants
↑Improves
?
High-density lipoprotein (HDL)
1 study155 participants
↑Improves
?
Insulin
1 study155 participants
↑Worsens
?
Low-density lipoprotein (LDL)
1 study155 participants
↓Improves
?
Serum Magnesium
1 study155 participants
↑Improves
?
Total cholesterol
1 study155 participants
↓Improves
?
Triglycerides
1 study155 participants
↓Improves
?
Weight
1 study155 participants
↓Improves
C
Glycemic Control
Small Improvement
1 study20 participants
small↑Improves
?
Insulin
1 study20 participants
↑Worsens
?
PCOS Symptoms
1 study20 participants
↓Improves
C
Bilirubin
Small Increase (potential liver harm)
1 study49 participants
small↑Worsens
D
Appetite
No effect
1 study49 participants
none
?
Weight
No significant effect
1 study49 participants
?
Body Fat
No significant effect
1 study49 participants
?
Blood Pressure
1 study49 participants
↑Worsens
?
Heart Rate
1 study49 participants
↑Worsens
?
Liver Enzymes
1 study49 participants
↑Worsens
?
Muscle Mass
1 study49 participants
↑Improves
C
Blood glucose
Small Improvement
1 study15 participants
small↓Improves
?
Glycemic Control
1 study15 participants
↑Improves
C
2-Arachidonoylglycerol Acid
Small Decrease
1 study63 participants
small↓Improves
?
Blood glucose
1 study63 participants
↓Improves
?
Insulin
1 study63 participants
↑Worsens
?
Weight
1 study63 participants
↓Improves
C
Arterial Stiffness
Small Improvement
1 study30 participants
small↓Improves
?
Blood Flow
3 studies149 participants
↑Improves
?
Blood Pressure
3 studies109 participants
↓Improves
?
Triglycerides
3 studies149 participants
↓Improves
?
Glycemic Control
2 studies79 participants
↑Improves
?
High-density lipoprotein (HDL)
2 studies79 participants
↑Improves
?
Insulin
2 studies100 participants
↑Worsens
?
Low-density lipoprotein (LDL)
2 studies79 participants
↓Improves
?
Total cholesterol
2 studies79 participants
↓Improves
?
Blood glucose
1 study70 participants
↓Improves
?
Cell Adhesion Factors
1 study70 participants
↓Improves
?
Fat Oxidation
1 study49 participants
↑Improves
?
Heart Rate
1 study49 participants
↓Improves
?
Interleukin 1-beta
1 study70 participants
↓Improves
?
Weight
1 study49 participants
↓Improves
C
Appetite
Small Decrease
1 study50 participants
small↓Improves
D
Weight
No effect
1 study50 participants
none
C
Appetite
Small Decrease
1 study10 participants
small↓Improves
?
Blood glucose
1 study10 participants
↑Worsens
?
Inflammation
1 study10 participants
↑Worsens
?
Insulin
1 study10 participants
↑Worsens
?
Metabolic Rate
1 study10 participants
↑Improves
?
Thermic effect of food (TEF)
1 study10 participants
↑Improves
D
Adiponectin
No effect
8 studies460 participants
none
?
Body Mass Index (BMI)
53 studies2867 participants
↓Improves
?
Weight
47 studies2867 participants
↓Improves
?
Waist circumference
24 studies2867 participants
↓Improves
?
Leptin
11 studies460 participants
↑Improves
?
High-density lipoprotein (HDL)
4 studies309 participants
↑Improves
?
Low-density lipoprotein (LDL)
4 studies309 participants
↓Improves
?
Total cholesterol
4 studies309 participants
↓Improves
?
Blood glucose
3 studies309 participants
↓Improves
?
C-Reactive Protein (CRP)
3 studies309 participants
↓Improves
?
Triglycerides
3 studies309 participants
↓Improves
D
Body Mass Index (BMI)
No effect
7 studies349 participants
none
?
Total cholesterol
7 studies318 participants
↓Improves
?
Triglycerides
7 studies318 participants
↓Improves
?
HbA1c
6 studies330 participants
↓Improves
?
Insulin Resistance
6 studies285 participants
↓Improves
D
Blood glucose
No effect
6 studies308 participants
none
?
Blood Pressure
6 studies308 participants
↓Improves
?
Weight
5 studies308 participants
↓Improves
?
Body Fat
4 studies308 participants
↓Improves
?
HbA1c
4 studies308 participants
↓Improves
?
Body Mass Index (BMI)
3 studies308 participants
↓Improves
?
Waist circumference
3 studies308 participants
↓Improves
?
C-Reactive Protein (CRP)
2 studies286 participants
↓Improves
?
High-density lipoprotein (HDL)
1 study76 participants
↑Improves
?
Inflammation
1 study76 participants
↓Improves
?
Interleukin 6
1 study210 participants
↓Improves
?
Low-density lipoprotein (LDL)
1 study76 participants
↓Improves
?
TNF-Alpha
1 study210 participants
↓Improves
?
Total cholesterol
1 study76 participants
↓Improves
?
Triglycerides
1 study76 participants
↓Improves
D
Body Fat
No effect
2 studies148 participants
none
?
Fat Oxidation
1 study10 participants
↑Improves
?
Low-density lipoprotein (LDL)
1 study41 participants
↓Improves
?
Metabolic Rate
1 study10 participants
↑Improves
?
Thermic effect of food (TEF)
1 study10 participants
↑Improves
D
Adiponectin
No effect
2 studies110 participants
none
?
Weight
8 studies353 participants
↓Improves
?
Body Fat
6 studies283 participants
↓Improves
?
Glycemic Control
4 studies154 participants
↑Improves
?
Muscle Mass
4 studies204 participants
↑Improves
?
Blood Pressure
2 studies115 participants
↓Improves
?
C-Reactive Protein (CRP)
2 studies42 participants
↓Improves
?
HbA1c
2 studies118 participants
↓Improves
?
High-density lipoprotein (HDL)
2 studies65 participants
↑Improves
?
Liver Enzymes
2 studies65 participants
↑Worsens
?
Metabolic Rate
2 studies77 participants
↑Improves
?
TNF-Alpha
2 studies42 participants
↓Improves
?
Triglycerides
2 studies65 participants
↓Improves
?
Blood glucose
1 study9 participants
↓Improves
?
DNA Damage
1 study29 participants
↑Worsens
?
Fat Oxidation
1 study23 participants
↑Improves
?
Heart Rate
1 study80 participants
↓Improves
?
Inflammation
1 study27 participants
↓Improves
?
Insulin
1 study9 participants
↑Worsens
?
LDL Oxidation
1 study27 participants
↓Improves
?
Leptin
1 study83 participants
↑Improves
?
Low-density lipoprotein (LDL)
1 study15 participants
↓Improves
?
Total Antioxidant Capacity (TAC)
1 study29 participants
↑Improves
D
Appetite
No effect
1 study74 participants
none
?
Total cholesterol
12 studies701 participants
↓Improves
?
Blood glucose
11 studies624 participants
↓Improves
?
Low-density lipoprotein (LDL)
11 studies637 participants
↓Improves
?
Weight
10 studies590 participants
↓Improves
?
Waist circumference
9 studies547 participants
↓Improves
?
Body Mass Index (BMI)
7 studies422 participants
↓Improves
?
Insulin Resistance
5 studies184 participants
↓Improves
?
HbA1c
4 studies300 participants
↓Improves
?
Hip Circumference
3 studies172 participants
↓Improves
?
Waist-Hip Ratio
3 studies156 participants
↑Improves
?
Creatinine
1 study75 participants
↑Improves
?
Depression Symptoms
1 study74 participants
↓Improves
?
High-density lipoprotein (HDL)
1 study75 participants
↑Improves
?
Sperm Count
1 study60 participants
↑Improves
?
Sperm Quality
1 study60 participants
↑Improves
?
Triglycerides
1 study75 participants
↓Improves
?
Urea
1 study75 participants
↑Improves
D
Adiponectin
No effect
1 study93 participants
none
?
Weight
3 studies482 participants
↓Improves
?
Blood Pressure
2 studies417 participants
↓Improves
?
High-density lipoprotein (HDL)
2 studies158 participants
↑Improves
?
Muscle Mass
2 studies158 participants
↑Improves
?
Blood Flow
1 study65 participants
↑Improves
?
Blood glucose
1 study93 participants
↓Improves
?
Body Fat
1 study65 participants
↓Improves
?
C-Reactive Protein (CRP)
1 study93 participants
↓Improves
?
Food Intake
1 study65 participants
↑Worsens
?
Glycemic Control
1 study93 participants
↑Improves
?
Insulin
1 study93 participants
↑Worsens
?
Leptin
1 study93 participants
↑Improves
?
Low-density lipoprotein (LDL)
1 study65 participants
↓Improves
?
TNF-Alpha
1 study93 participants
↓Improves
?
Triglycerides
1 study93 participants
↓Improves
D
Blood glucose
No effect
1 study32 participants
none
?
Blood Pressure
1 study32 participants
↓Improves
?
Body Fat
1 study32 participants
↓Improves
?
High-density lipoprotein (HDL)
1 study32 participants
↑Improves
?
Liver Enzymes
1 study32 participants
↑Worsens
?
Low-density lipoprotein (LDL)
1 study32 participants
↓Improves
?
Total cholesterol
1 study32 participants
↓Improves
?
Triglycerides
1 study32 participants
↓Improves
?
Weight
1 study32 participants
↓Improves
D
Appetite
No effect
1 study30 participants
none
?
Blood glucose
1 study30 participants
↓Improves
?
Blood Pressure
1 study30 participants
↓Improves
?
Heart Rate
1 study30 participants
↓Improves
?
Hip Circumference
1 study30 participants
↓Improves
?
Insulin
1 study30 participants
↑Worsens
?
Insulin Resistance
1 study30 participants
↓Improves
?
Waist circumference
1 study30 participants
↓Improves
?
Waist-Hip Ratio
1 study30 participants
↑Improves
?
Weight
1 study30 participants
↓Improves
D
Adiponectin
No effect
1 study25 participants
none
?
Blood glucose
4 studies134 participants
↓Improves
?
Weight
4 studies134 participants
↓Improves
?
Body Fat
3 studies118 participants
↓Improves
?
Insulin
3 studies109 participants
↑Worsens
?
Blood Pressure
2 studies83 participants
↓Improves
?
High-density lipoprotein (HDL)
2 studies83 participants
↑Improves
?
Muscle Mass
2 studies60 participants
↑Improves
?
Total cholesterol
2 studies83 participants
↓Improves
?
Triglycerides
2 studies83 participants
↓Improves
?
Bilirubin
1 study58 participants
↑Worsens
?
Blood Lactate (Exercise)
1 study16 participants
↑Worsens
?
C-Reactive Protein (CRP)
1 study58 participants
↓Improves
?
Cell Adhesion Factors
1 study58 participants
↓Improves
?
Glycemic Control
1 study25 participants
↑Improves
?
Glycogen
1 study16 participants
↑Improves
?
Glycogen Resynthesis
1 study16 participants
↑Improves
?
Kidney Function
1 study58 participants
↑Improves
?
Liver Enzymes
1 study58 participants
↑Worsens
?
Low-density lipoprotein (LDL)
1 study58 participants
↓Improves
D
Arterial Stiffness
No effect
1 study225 participants
none
?
Body Mass Index (BMI)
6 studies337 participants
↓Improves
?
Weight
5 studies307 participants
↓Improves
?
Body Fat
4 studies184 participants
↓Improves
?
Waist circumference
4 studies290 participants
↓Improves
?
Triglycerides
3 studies93 participants
↓Improves
?
High-density lipoprotein (HDL)
2 studies70 participants
↑Improves
?
Insulin
2 studies181 participants
↑Worsens
?
Low-density lipoprotein (LDL)
2 studies70 participants
↓Improves
?
Blood glucose
1 study225 participants
↓Improves
?
Blood Pressure
1 study225 participants
↓Improves
?
Food Intake
1 study77 participants
↑Worsens
?
Glycemic Control
1 study89 participants
↑Improves
?
HbA1c
1 study92 participants
↓Improves
?
Inflammation
1 study225 participants
↓Improves
?
Insulin Resistance
1 study225 participants
↓Improves
?
Muscle Mass
1 study77 participants
↑Improves
?
Parathyroid Hormone
1 study77 participants
↑Improves
?
Pulse Wave Velocity
1 study225 participants
↓Improves
?
Testosterone
1 study165 participants
↑Improves
?
Vascular Function
1 study225 participants
↑Improves
D
Condition-Related Fatigue
No effect
1 study57 participants
none
?
Cortisol
1 study57 participants
↓Improves
?
Estrogen
1 study57 participants
↑Worsens
?
Serum DHEA
1 study57 participants
↑Improves
?
Testosterone
1 study57 participants
↑Improves
?
Fatigue Symptoms
1 study57 participants
↑Worsens
D
Blood glucose
No effect
1 study26 participants
none
?
Blood Pressure
1 study26 participants
↓Improves
?
Body Fat
1 study26 participants
↓Improves
?
C-Reactive Protein (CRP)
1 study26 participants
↓Improves
?
Erythrocyte Sedimentation Rate
1 study26 participants
↓Improves
?
Heart Rate
1 study26 participants
↓Improves
?
High-density lipoprotein (HDL)
1 study26 participants
↑Improves
?
Insulin
1 study26 participants
↑Worsens
?
Low-density lipoprotein (LDL)
1 study26 participants
↓Improves
?
Monocyte Chemoattractant Protein-1
1 study26 participants
↑Improves
?
Total cholesterol
1 study26 participants
↓Improves
?
Triglycerides
1 study26 participants
↓Improves
?
Uric Acid
1 study26 participants
↓Improves
?
vLDL-C
1 study26 participants
↓Improves
D
Glycemic Control
No effect
1 study14 participants
none
?
High-density lipoprotein (HDL)
1 study14 participants
↑Improves
?
Low-density lipoprotein (LDL)
1 study14 participants
↓Improves
?
Total cholesterol
1 study14 participants
↓Improves
?
Triglycerides
1 study14 participants
↓Improves
D
Arterial Stiffness
No effect
1 study64 participants
none
?
Blood glucose
2 studies144 participants
↓Improves
?
Blood Pressure
2 studies144 participants
↓Improves
?
Weight
2 studies144 participants
↓Improves
?
Body Fat
1 study64 participants
↓Improves
?
C-Reactive Protein (CRP)
1 study64 participants
↓Improves
?
Cortisol
1 study80 participants
↓Improves
?
Glycemic Control
1 study80 participants
↑Improves
?
High-density lipoprotein (HDL)
1 study80 participants
↑Improves
?
Insulin
1 study80 participants
↑Worsens
?
Interleukin 10
1 study64 participants
↑Improves
?
Interleukin 6
1 study64 participants
↓Improves
?
Interleukin 8
1 study64 participants
↑Worsens
?
LDL Oxidation
1 study64 participants
↓Improves
?
Liver Fat
1 study80 participants
↓Improves
?
Low-density lipoprotein (LDL)
1 study80 participants
↓Improves
?
Oxidative Stress Biomarkers
1 study64 participants
↓Improves
?
TNF-Alpha
1 study64 participants
↓Improves
?
Total cholesterol
1 study80 participants
↓Improves
?
Triglycerides
1 study80 participants
↓Improves
D
Body Fat
No effect
1 study26 participants
none
?
Fatigue Symptoms
1 study26 participants
↓Improves
?
Weight
1 study26 participants
↓Improves
D
Blood Pressure
No effect
1 study47 participants
none
?
Weight
2 studies158 participants
↓Improves
?
Glycemic Control
1 study47 participants
↑Improves
?
High-density lipoprotein (HDL)
1 study47 participants
↑Improves
?
Insulin
1 study47 participants
↑Worsens
?
Low-density lipoprotein (LDL)
1 study47 participants
↓Improves
?
Thermic effect of food (TEF)
1 study10 participants
↑Improves
?
Triglycerides
1 study47 participants
↓Improves
D
Body Fat
No effect
1 study637 participants
none
?
Body Mass Index (BMI)
1 study637 participants
↓Improves
?
Muscle Mass
1 study637 participants
↑Improves
?
Weight
1 study637 participants
↓Improves
D
Blood glucose
No effect
1 study23 participants
none
?
Blood Pressure
1 study23 participants
↑Worsens
?
Body Fat
1 study23 participants
↑Worsens
?
Estrogen
1 study23 participants
↑Worsens
?
Fatigue Symptoms
1 study23 participants
↑Worsens
?
Parathyroid Hormone
1 study23 participants
↑Improves
?
Serum T3
1 study23 participants
↑Improves
?
Serum T4
1 study23 participants
↑Improves
?
Testosterone
1 study23 participants
↑Improves
?
Weight
1 study23 participants
↑Worsens
?
Weight
2 studies179 participants
↓Improves
?
Blood Pressure
Small Detriment
1 study112 participants
small
?
Body Fat
1 study67 participants
↓Improves
?
Metabolic Rate
1 study12 participants
↑Improves
?
Triglycerides
1 study67 participants
↓Improves
?
Hearing Loss
2 studies278 participants
↑Improves
?
Blood glucose
1 study16 participants
↓Improves
Research Citations (3)
Related Conditions
Obesity
35 shared supplements · 525 outcomes
Obesity is a condition of excessive body fat that increases the risk for other conditions such as diabetes and heart disease. Fat is how the body stores extra calories that were eaten but not used. Obesity treatment usually involves restricting the calories eaten or creating a negative calorie balance.
Type 2 Diabetes
31 shared supplements · 868 outcomes
Type 2 diabetes (T2D) is a disease in which blood glucose levels are too high. It is characterized by insulin resistance in muscle, fat, and pancreas cells and an inability of the pancreas to manufacture enough insulin to control blood glucose levels. T2D is strongly associated with excess body fat, and weight loss induced by lifestyle changes is extremely effective for treating T2D.
Metabolic Health
31 shared supplements · 975 outcomes
Research on metabolism, blood glucose regulation, insulin sensitivity, and metabolic syndrome.
26 shared supplements · outcomes
Weight Loss & Maintenance
23 shared supplements · 433 outcomes
This goal refers to people with a BMI >25 attempting to reach/maintain their ideal weight. While interventions that work for people with a BMI >25 may also work for people with a lower BMI, the context is often sufficiently different that this isn't assured.
High Cholesterol
22 shared supplements · 553 outcomes
High amounts of low-density lipoproteins cause fatty plaques to build up in the arteries, which restricts blood flow and can cause health problems like a heart attack. Lifestyle factors (e.g., poor diet, smoking) and genetics play a huge role in blood cholesterol levels.
Metabolic Syndrome
20 shared supplements · 391 outcomes
Metabolic syndrome refers to a group of cardiometabolic risk factors: abdominal obesity, high blood pressure, high fasting blood sugar, high blood triglycerides, and low HDL-C. If a person has at least three of these, they have metabolic syndrome.
High Blood Pressure
20 shared supplements · 393 outcomes
High blood pressure is when the force of your blood pushing against the walls of the arteries is consistently too high. High blood pressure is often caused by an unhealthy lifestyle, although it can result from other medical conditions as well.