Supplement

Rose Hip

Rose hip is the vitamin C-rich fruit left after a rose blooms, and it holds plant compounds that act as antioxidants. The evidence is limited, but skin dryness improved in a small trial of 34 people, and chemotaxis, the movement of immune cells toward inflammation, went down in a study of just eight. C-reactive protein and blood glucose showed no clear difference, and the studies were small.

Sources: PMID 17657440; PMID 21420288

Updated 30 September 2026
How we grade
9 studies cited

Best evidence: Grade C
Conditions studied: 10
Outcomes: 86
Graded outcomes: 0029

Evidence by condition

Strong
Moderate
Limited
Very limited

10 conditions

Osteoarthritis (OA)

Osteoarthritis (OA): outcomes studied for Rose Hip
Grade	Outcome	Effect	Size	Studies	People
	Chemotaxis Small Decrease	Improves (the measure goes down)	Small effect		8 people
	C-Reactive Protein (CRP) No effect		NoneNo effect	3 studies	8 people
Studies that measured c-reactive protein (crp) Rose hip inhibits chemotaxis and chemiluminescence of human peripheral blood neutrophils in vitro and reduces certain inflammatory parameters in vivoInflammopharmacology · PMID 17657440 The effects of rose hip (Rosa canina) on plasma antioxidative activity and C-reactive protein in patients with rheumatoid arthritis and normal controls: a prospective cohort studyPhytomedicine · PMID 21420288 Rose hip herbal remedy in patients with rheumatoid arthritis - a randomised controlled trialPhytomedicine · PMID 19818588
	Pain	Improves (the measure goes down)		2 studies	93 people
Studies that measured pain A herbal remedy, Hyben Vital (stand. powder of a subspecies of Rosa canina fruits), reduces pain and improves general wellbeing in patients with osteoarthritis--a double-blind, placebo-controlled, randomised trialPhytomedicine · PMID 15330493 The anti-inflammatory properties of rose-hipInflammopharmacology · PMID 17657447
	Osteoarthritis Symptoms	Improves (the measure goes down)		1 study	261 people
Studies that measured osteoarthritis symptoms A powder made from seeds and shells of a rose-hip subspecies (Rosa canina) reduces symptoms of knee and hip osteoarthritis: a randomized, double-blind, placebo-controlled clinical trialScand J Rheumatol · PMID 16195164

Skin Health

Skin Health: outcomes studied for Rose Hip
Grade	Outcome	Effect	Size	Studies	People
	Skin Dryness Small Improvement	Improves (the measure goes up)	Small effect		34 people
	Wrinkles	Improves (the measure goes up)		1 study	34 people
Studies that measured wrinkles The effectiveness of a standardized rose hip powder, containing seeds and shells of Rosa canina, on cell longevity, skin wrinkles, moisture, and elasticityClin Interv Aging · PMID 26604725
	Skin Elasticity	Improves (the measure goes up)			34 people

Immune Health

C-Reactive Protein (CRP)
Chemotaxis: changes; see studies
Liver Enzymes: changes; see studies

Immune Health: outcomes studied for Rose Hip
Grade	Outcome	Effect	Size	Studies	People
	C-Reactive Protein (CRP) No effect		NoneNo effect	3 studies	13 people
Studies that measured c-reactive protein (crp) Rose hip inhibits chemotaxis and chemiluminescence of human peripheral blood neutrophils in vitro and reduces certain inflammatory parameters in vivoInflammopharmacology · PMID 17657440 The effects of rose hip (Rosa canina) on plasma antioxidative activity and C-reactive protein in patients with rheumatoid arthritis and normal controls: a prospective cohort studyPhytomedicine · PMID 21420288 Rose hip herbal remedy in patients with rheumatoid arthritis - a randomised controlled trialPhytomedicine · PMID 19818588
	Chemotaxis	Changes; see studies			13 people
	Liver Enzymes	Changes; see studies			13 people

Rheumatoid Arthritis (RA)

Anti-Oxidant Enzyme Profile
C-Reactive Protein (CRP): improves
Pain: improves

Rheumatoid Arthritis (RA): outcomes studied for Rose Hip
Grade	Outcome	Effect	Size	Studies	People
	Anti-Oxidant Enzyme Profile No effect		NoneNo effect		30 people
	C-Reactive Protein (CRP)	Improves (the measure goes down)		3 studies	119 people
Studies that measured c-reactive protein (crp) Rose hip inhibits chemotaxis and chemiluminescence of human peripheral blood neutrophils in vitro and reduces certain inflammatory parameters in vivoInflammopharmacology · PMID 17657440 The effects of rose hip (Rosa canina) on plasma antioxidative activity and C-reactive protein in patients with rheumatoid arthritis and normal controls: a prospective cohort studyPhytomedicine · PMID 21420288 Rose hip herbal remedy in patients with rheumatoid arthritis - a randomised controlled trialPhytomedicine · PMID 19818588
	Pain	Improves (the measure goes down)		2 studies	119 people
Studies that measured pain A herbal remedy, Hyben Vital (stand. powder of a subspecies of Rosa canina fruits), reduces pain and improves general wellbeing in patients with osteoarthritis--a double-blind, placebo-controlled, randomised trialPhytomedicine · PMID 15330493 The anti-inflammatory properties of rose-hipInflammopharmacology · PMID 17657447
	Rheumatoid Arthritis Symptoms	Improves (the measure goes down)			119 people
	TNF-Alpha	Improves (the measure goes down)			89 people
	Total cholesterol	Improves (the measure goes down)			89 people

Coronary Artery Disease (CAD)

Adiponectin
C-Reactive Protein (CRP): improves
Glycemic Control: improves

Coronary Artery Disease (CAD): outcomes studied for Rose Hip
Grade	Outcome	Effect	Size	Studies	People
	Adiponectin No effect		NoneNo effect		31 people
	C-Reactive Protein (CRP)	Improves (the measure goes down)		3 studies	31 people
Studies that measured c-reactive protein (crp) Rose hip inhibits chemotaxis and chemiluminescence of human peripheral blood neutrophils in vitro and reduces certain inflammatory parameters in vivoInflammopharmacology · PMID 17657440 The effects of rose hip (Rosa canina) on plasma antioxidative activity and C-reactive protein in patients with rheumatoid arthritis and normal controls: a prospective cohort studyPhytomedicine · PMID 21420288 Rose hip herbal remedy in patients with rheumatoid arthritis - a randomised controlled trialPhytomedicine · PMID 19818588
	Glycemic Control	Improves (the measure goes up)		1 study	31 people
Studies that measured glycemic control Effects of rose hip intake on risk markers of type 2 diabetes and cardiovascular disease: a randomized, double-blind, cross-over investigation in obese personsEur J Clin Nutr · PMID 22166897
	Blood glucose	Improves (the measure goes down)			31 people
	Blood Pressure	Improves (the measure goes down)			31 people
	HbA1c	Improves (the measure goes down)			31 people
	High-density lipoprotein (HDL)	Improves (the measure goes up)			31 people
	Insulin	Changes; see studies			31 people
	Liver Enzymes	Changes; see studies			31 people
	Low-density lipoprotein (LDL)	Improves (the measure goes down)			31 people
	Total cholesterol	Improves (the measure goes down)			31 people
	Triglycerides	Improves (the measure goes down)			31 people
	Weight	Improves (the measure goes down)			31 people

High Cholesterol

Adiponectin
C-Reactive Protein (CRP): improves
Glycemic Control: improves

High Cholesterol: outcomes studied for Rose Hip
Grade	Outcome	Effect	Size	Studies	People
	Adiponectin No effect		NoneNo effect		31 people
	C-Reactive Protein (CRP)	Improves (the measure goes down)		3 studies	31 people
Studies that measured c-reactive protein (crp) Rose hip inhibits chemotaxis and chemiluminescence of human peripheral blood neutrophils in vitro and reduces certain inflammatory parameters in vivoInflammopharmacology · PMID 17657440 The effects of rose hip (Rosa canina) on plasma antioxidative activity and C-reactive protein in patients with rheumatoid arthritis and normal controls: a prospective cohort studyPhytomedicine · PMID 21420288 Rose hip herbal remedy in patients with rheumatoid arthritis - a randomised controlled trialPhytomedicine · PMID 19818588
	Glycemic Control	Improves (the measure goes up)		1 study	31 people
Studies that measured glycemic control Effects of rose hip intake on risk markers of type 2 diabetes and cardiovascular disease: a randomized, double-blind, cross-over investigation in obese personsEur J Clin Nutr · PMID 22166897
	Blood glucose	Improves (the measure goes down)			31 people
	Blood Pressure	Improves (the measure goes down)			31 people
	HbA1c	Improves (the measure goes down)			31 people
	High-density lipoprotein (HDL)	Improves (the measure goes up)			31 people
	Insulin	Changes; see studies			31 people
	Liver Enzymes	Changes; see studies			31 people
	Low-density lipoprotein (LDL)	Improves (the measure goes down)			31 people
	Total cholesterol	Improves (the measure goes down)			31 people
	Triglycerides	Improves (the measure goes down)			31 people
	Weight	Improves (the measure goes down)			31 people

Obesity

Blood glucose
Body Fat: improves
Blood Pressure: improves

Obesity: outcomes studied for Rose Hip
Grade	Outcome	Effect	Size	Studies	People
	Blood glucose No effect		NoneNo effect		32 people
	Body Fat	Improves (the measure goes down)		1 study	32 people
Studies that measured body fat Daily intake of rosehip extract decreases abdominal visceral fat in preobese subjects: a randomized, double-blind, placebo-controlled clinical trialDiabetes Metab Syndr Obes · PMID 25834460
	Blood Pressure	Improves (the measure goes down)			32 people
	High-density lipoprotein (HDL)	Improves (the measure goes up)			32 people
	Liver Enzymes	Changes; see studies			32 people
	Low-density lipoprotein (LDL)	Improves (the measure goes down)			32 people
	Total cholesterol	Improves (the measure goes down)			32 people
	Triglycerides	Improves (the measure goes down)			32 people
	Weight	Improves (the measure goes down)			32 people

Type 2 Diabetes

Adiponectin
C-Reactive Protein (CRP): improves
Glycemic Control: improves

Type 2 Diabetes: outcomes studied for Rose Hip
Grade	Outcome	Effect	Size	Studies	People
	Adiponectin No effect		NoneNo effect		31 people
	C-Reactive Protein (CRP)	Improves (the measure goes down)		3 studies	31 people
Studies that measured c-reactive protein (crp) Rose hip inhibits chemotaxis and chemiluminescence of human peripheral blood neutrophils in vitro and reduces certain inflammatory parameters in vivoInflammopharmacology · PMID 17657440 The effects of rose hip (Rosa canina) on plasma antioxidative activity and C-reactive protein in patients with rheumatoid arthritis and normal controls: a prospective cohort studyPhytomedicine · PMID 21420288 Rose hip herbal remedy in patients with rheumatoid arthritis - a randomised controlled trialPhytomedicine · PMID 19818588
	Glycemic Control	Improves (the measure goes up)		1 study	31 people
Studies that measured glycemic control Effects of rose hip intake on risk markers of type 2 diabetes and cardiovascular disease: a randomized, double-blind, cross-over investigation in obese personsEur J Clin Nutr · PMID 22166897
	Blood glucose	Improves (the measure goes down)			31 people
	Blood Pressure	Improves (the measure goes down)			31 people
	HbA1c	Improves (the measure goes down)			31 people
	High-density lipoprotein (HDL)	Improves (the measure goes up)			31 people
	Insulin	Changes; see studies			31 people
	Liver Enzymes	Changes; see studies			31 people
	Low-density lipoprotein (LDL)	Improves (the measure goes down)			31 people
	Total cholesterol	Improves (the measure goes down)			31 people
	Triglycerides	Improves (the measure goes down)			31 people
	Weight	Improves (the measure goes down)			31 people

Overweight

Blood glucose
Body Fat: improves
Blood Pressure: improves

Overweight: outcomes studied for Rose Hip
Grade	Outcome	Effect	Size	Studies	People
	Blood glucose No effect		NoneNo effect		32 people
	Body Fat	Improves (the measure goes down)		1 study	32 people
Studies that measured body fat Daily intake of rosehip extract decreases abdominal visceral fat in preobese subjects: a randomized, double-blind, placebo-controlled clinical trialDiabetes Metab Syndr Obes · PMID 25834460
	Blood Pressure	Improves (the measure goes down)			32 people
	High-density lipoprotein (HDL)	Improves (the measure goes up)			32 people
	Liver Enzymes	Changes; see studies			32 people
	Low-density lipoprotein (LDL)	Improves (the measure goes down)			32 people
	Total cholesterol	Improves (the measure goes down)			32 people
	Triglycerides	Improves (the measure goes down)			32 people
	Weight	Improves (the measure goes down)			32 people

Weight Loss & Maintenance

Adiponectin
C-Reactive Protein (CRP): improves
Glycemic Control: improves

Weight Loss & Maintenance: outcomes studied for Rose Hip
Grade	Outcome	Effect	Size	Studies	People
	Adiponectin No effect		NoneNo effect		31 people
	C-Reactive Protein (CRP)	Improves (the measure goes down)		3 studies	31 people
Studies that measured c-reactive protein (crp) Rose hip inhibits chemotaxis and chemiluminescence of human peripheral blood neutrophils in vitro and reduces certain inflammatory parameters in vivoInflammopharmacology · PMID 17657440 The effects of rose hip (Rosa canina) on plasma antioxidative activity and C-reactive protein in patients with rheumatoid arthritis and normal controls: a prospective cohort studyPhytomedicine · PMID 21420288 Rose hip herbal remedy in patients with rheumatoid arthritis - a randomised controlled trialPhytomedicine · PMID 19818588
	Glycemic Control	Improves (the measure goes up)		1 study	31 people
Studies that measured glycemic control Effects of rose hip intake on risk markers of type 2 diabetes and cardiovascular disease: a randomized, double-blind, cross-over investigation in obese personsEur J Clin Nutr · PMID 22166897
	Blood glucose	Improves (the measure goes down)			31 people
	Blood Pressure	Improves (the measure goes down)			31 people
	HbA1c	Improves (the measure goes down)			31 people
	High-density lipoprotein (HDL)	Improves (the measure goes up)			31 people
	Insulin	Changes; see studies			31 people
	Liver Enzymes	Changes; see studies			31 people
	Low-density lipoprotein (LDL)	Improves (the measure goes down)			31 people
	Total cholesterol	Improves (the measure goes down)			31 people
	Triglycerides	Improves (the measure goes down)			31 people
	Weight	Improves (the measure goes down)			31 people

Key findings

ChemotaxisOsteoarthritis (OA)Improves (the measure goes down)
Skin DrynessSkin HealthImproves (the measure goes up)
C-Reactive Protein (CRP)Osteoarthritis (OA)

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Grade C

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Studies cited

9 studies from PubMed

The effectiveness of a standardized rose hip powder, containing seeds and shells of Rosa canina, on cell longevity, skin wrinkles, moisture, and elasticityClin Interv Aging · PMID 26604725
Rose hip inhibits chemotaxis and chemiluminescence of human peripheral blood neutrophils in vitro and reduces certain inflammatory parameters in vivoInflammopharmacology · PMID 17657440
Effects of rose hip intake on risk markers of type 2 diabetes and cardiovascular disease: a randomized, double-blind, cross-over investigation in obese personsEur J Clin Nutr · PMID 22166897
The effects of rose hip (Rosa canina) on plasma antioxidative activity and C-reactive protein in patients with rheumatoid arthritis and normal controls: a prospective cohort studyPhytomedicine · PMID 21420288
Rose hip herbal remedy in patients with rheumatoid arthritis - a randomised controlled trialPhytomedicine · PMID 19818588
A herbal remedy, Hyben Vital (stand. powder of a subspecies of Rosa canina fruits), reduces pain and improves general wellbeing in patients with osteoarthritis--a double-blind, placebo-controlled, randomised trialPhytomedicine · PMID 15330493
The anti-inflammatory properties of rose-hipInflammopharmacology · PMID 17657447
A powder made from seeds and shells of a rose-hip subspecies (Rosa canina) reduces symptoms of knee and hip osteoarthritis: a randomized, double-blind, placebo-controlled clinical trialScand J Rheumatol · PMID 16195164
Daily intake of rosehip extract decreases abdominal visceral fat in preobese subjects: a randomized, double-blind, placebo-controlled clinical trialDiabetes Metab Syndr Obes · PMID 25834460

Evidence by condition

Key findings

Shop Rose Hip

Studies cited

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