Alpha-Linolenic Acid (ALA)
ALA is the plant-based omega-3 fatty acid found in flaxseed, chia, walnuts, and hemp. It's an ESSENTIAL fatty acid but NOT equivalent to fish omega-3s (EPA/DHA). IMPORTANT: Conversion to EPA/DHA is very poor (<5-10%). D-grade evidence for cardiovascular outcomes - no effect on all-cause mortality or major cardiac events. B-grade for blood pressure (mixed effects). For omega-3 benefits, EPA/DHA from fish or algae oil are superior. ALA may have modest independent anti-inflammatory effects.
Quick Answer
What it is
ALA is the plant-based omega-3 fatty acid found in flaxseed, chia, walnuts, and hemp. It's an ESSENTIAL fatty acid but NOT equivalent to fish omega-3s (EPA/DHA).
Key findings
- Grade B: Blood Pressure (Obesity)
- Grade D: High-density lipoprotein (HDL) (Dyslipidemia)
- Grade D: All-Cause Mortality
Safety
No specific caution or interaction language was detected in the current summary/outcome notes.
ℹ️ Quick Facts: Alpha-Linolenic Acid (ALA)
Quick Facts: Alpha-Linolenic Acid (ALA)
- Best Evidence:Grade B
- Conditions Studied:9
- Research Outcomes:62
- Grade B Findings:2
- Key Effect:Obesity
Detailed Outcomes
Evidence by Condition
Best grade per condition (each condition may have multiple outcomes)
Research Citations (6)
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