African Mango

African mango (Irvingia gabonensis) seed extract is marketed for weight loss. CAUTION: Evidence is LOW QUALITY. C-grade outcomes only, based on small studies (40-102 participants) with methodological concerns. Claimed weight loss effects appear too good to be true (5-13kg in 4-10 weeks). The main researcher (Ngondi/Oben) has published suspiciously impressive results with conflict of interest. Contains soluble fiber and possibly leptin-modulating compounds. May have modest metabolic effects but extraordinary claims are not supported by independent replication.

Quick Answer

What it is

African mango (Irvingia gabonensis) seed extract is marketed for weight loss. CAUTION: Evidence is LOW QUALITY.

Key findings

  • Grade C: Adiponectin (Obesity)
  • Grade C: Blood glucose (Obesity)
  • Grade N/A: High-density lipoprotein (HDL) (Obesity)

Safety

  • CAUTION: Evidence is LOW QUALITY.
ℹ️ Quick Facts: African Mango

Quick Facts: African Mango

  • Best Evidence:Grade C
  • Conditions Studied:4
  • Research Outcomes:28
  • Key Effect:Obesity
Outcomes by grade:
A0
B0
C6
D0
4 conditions Β· 28 outcomes

Detailed Outcomes

|
C
Adiponectin
Small increase in adiponectin
1 study
small↑Improves
C
Blood glucose
Small improvement in blood glucose
1 study
small↓Improves
?
High-density lipoprotein (HDL)
2 studies
↑Improves
?
Low-density lipoprotein (LDL)
2 studies
↑Worsens
?
Total cholesterol
↑Worsens
?
Weight
2 studies
↑Worsens
?
Blood Pressure
1 study
↑Worsens
?
Body Fat
1 study
↑Worsens
?
C-Reactive Protein (CRP)
1 study
↑Worsens
?
Leptin
1 study
↑Improves
?
Triglycerides
1 study
↑Worsens
C
Blood glucose
Small improvement in blood glucose
1 study
small↓Improves
C
Blood glucose
Small improvement in blood glucose
1 study
small↓Improves
C
Adiponectin
Small increase in adiponectin
1 study
small↑Improves
?
Body Fat
1 study
↑Worsens
?
C-Reactive Protein (CRP)
1 study
↑Worsens
?
High-density lipoprotein (HDL)
1 study
↑Improves
?
Leptin
1 study
↑Improves
?
Low-density lipoprotein (LDL)
1 study
↑Worsens
?
Total cholesterol
↑Worsens
?
Weight
1 study
↑Worsens
C
Blood glucose
Small improvement in blood glucose
1 study
small↓Improves
?
Blood Pressure
1 study
↑Worsens
?
High-density lipoprotein (HDL)
1 study
↑Improves
?
Low-density lipoprotein (LDL)
1 study
↑Worsens
?
Total cholesterol
↑Worsens
?
Triglycerides
1 study
↑Worsens
?
Weight
1 study
↑Worsens

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