Pyruvate

Pyruvate is an energy intermediate in cells, derived from both glucose and fatty acids to produce ATP. Despite this importance, human studies are not overly promising and the high doses needed are sometimes limited by intestinal side-effects.

Quick Answer

What it is

Pyruvate is an energy intermediate in cells, derived from both glucose and fatty acids to produce ATP. Despite this importance, human studies are not overly promising and the high doses needed are sometimes limited by intestinal side-effects.

Key findings

  • Grade C: Fatigue Symptoms (Body Composition)
  • Grade C: Blood Pressure (High Cholesterol)
  • Grade D: Body Fat (Body Composition)

Safety

No specific caution or interaction language was detected in the current summary/outcome notes.

ℹ️ Quick Facts: Pyruvate

Quick Facts: Pyruvate

  • Best Evidence:Grade C
  • Conditions Studied:12
  • Research Outcomes:31
  • Key Effect:Body Composition
Outcomes by grade:
A0
B0
C2
D6
12 conditions · 31 outcomes

Detailed Outcomes

Grade:
Effect:
Size:
Sort:
|
C
Fatigue Symptoms
Small Improvement
1 study
smallImproves
D
Body Fat
No effect
none
?
Weight
Improves
?
Power Output
Improves
?
Training Volume
1 study
Improves
C
Blood Pressure
Small Improvement
1 study
smallImproves
?
High-density lipoprotein (HDL)
Improves
?
Low-density lipoprotein (LDL)
2 studies
Improves
?
Heart Rate
1 study
Improves
?
Total cholesterol
1 study
Improves
?
Weight
Improves
D
Body Fat
No effect
none
?
Weight
Improves
?
High-density lipoprotein (HDL)
Improves
?
Low-density lipoprotein (LDL)
1 study
Improves
D
Aerobic Exercise Metrics
No effect
none
?
Body Fat
Improves
?
Power Output
Improves
?
Training Volume
1 study
Improves
D
Body Fat
No effect
none
?
Weight
Improves
D
Body Fat
No effect
none
?
Weight
Improves
D
Body Fat
No effect
none
?
Fatigue Symptoms
1 study
Improves
?
Weight
Improves
?
Aerobic Exercise Metrics
Improves
?
Power Output
Improves
?
Aerobic Exercise Metrics
Improves
?
Body Fat
Improves
?
Power Output
Improves

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