Premenstrual Syndrome (PMS)
PMS stands for premenstrual syndrome. PMS involves physical symptoms such as pain, bloating, and acne along with mood changes that occur prior to menstruation.
Quick Answer
What it is
PMS stands for premenstrual syndrome. PMS involves physical symptoms such as pain, bloating, and acne along with mood changes that occur prior to menstruation.
Key findings
- Grade A: PMS Symptoms (Lemon Balm)
- Grade A: Breast Tenderness (Chaste tree)
- Grade B: Anxiety Symptoms (Vitamin D)
Safety
No specific caution or interaction language was detected in the current summary/outcome notes.
ℹ️ Quick Facts
Quick Facts: Premenstrual Syndrome (PMS)
- Supplements Studied:19
- Research Trials:50
- Total Participants:7,310
- Grade A Supplements:2
- Top Supplement:Lemon Balm (A)
Evidence-Based Protocol
Supplement stack ranked by research quality
Primary Stack (Tier 1)
Modulates dopamine and prolactin levels, helping regulate the menstrual cycle and reduce PMS symptoms
Addresses menstrual cycle-related calcium fluctuations that contribute to mood and physical symptoms
Supporting Stack (Tier 2)
Cofactor for serotonin and dopamine synthesis, reducing mood-related PMS symptoms
Reduces bloating, headaches, and mood symptoms; often depleted in the luteal phase
How It Works
Premenstrual syndrome affects up to 90% of women to some degree, with 20-30% experiencing moderate to severe symptoms. PMS occurs in the luteal phase (after ovulation, before menstruation) and involves mood changes, bloating, breast tenderness, headaches, and fatigue. The exact cause isn't fully understood but involves hormonal fluctuations affecting neurotransmitters.
Expected timeline: Vitex takes 2-3 cycles (months) for full effect. Calcium, B6, and magnesium may show benefits within 1-2 cycles. Start supplements at least one cycle before expected benefit.
Supplements for Premenstrual Syndrome (PMS)
Sorted by strength of evidence
Detailed Outcomes
Research Citations (100)
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