Calcium
Calcium is an essential macromineral critical for bone health, muscle function, and nerve transmission. B-GRADE for depression symptoms in PMS (2 studies, 245 participants - small improvement) and fecal bile acids. D-GRADE for all-cause mortality (no effect) and free testosterone (no effect). Best obtained through diet (dairy, leafy greens, fortified foods). Supplementation recommended when dietary intake is insufficient, especially in postmenopausal women and those at osteoporosis risk. Calcium citrate is better absorbed than carbonate, especially without food. SAFETY NOTE: High-dose supplementation (>1000mg/day) may increase cardiovascular risk - controversial but warrants caution.
Quick Answer
What it is
Calcium is an essential macromineral critical for bone health, muscle function, and nerve transmission. B-GRADE for depression symptoms in PMS (2 studies, 245 participants - small improvement) and fecal bile acids.
Key findings
- Grade A: Pre-Eclampsia Risk (Preeclampsia)
- Grade B: PMS Symptoms (Primary Dysmenorrhea (Menstrual Cramps))
- Grade B: Depression Symptoms (Premenstrual Syndrome (PMS))
Safety
- Supplementation recommended when dietary intake is insufficient, especially in postmenopausal women and those at osteoporosis risk.
- SAFETY NOTE: High-dose supplementation (>1000mg/day) may increase cardiovascular risk - controversial but warrants caution.
ℹ️ Quick Facts: Calcium
Quick Facts: Calcium
- Best Evidence:Grade A
- Conditions Studied:15
- Research Outcomes:32
- Grade A Findings:1
- Grade B Findings:3
- Key Effect:Preeclampsia
Detailed Outcomes
Evidence by Condition
Best grade per condition (each condition may have multiple outcomes)
Research Citations (22)
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