Supplement

Royal Jelly

Royal jelly is a protein- and fat-rich substance that worker bees produce to feed queen bee larvae. People mostly look at it for metabolic health, and blood glucose improved in a small group of 71 people, though the evidence is limited. Blood pressure and a marker of inflammation called CRP showed no clear difference, and the evidence there is very limited, so the research is still thin.

Updated 30 September 2026
How we grade
5 studies cited

Best evidence: Grade C
Conditions studied: 5
Outcomes: 28
Graded outcomes: 0022

Evidence by condition

Strong
Moderate
Limited
Very limited

5 conditions

Metabolic Health

Metabolic Health: outcomes studied for Royal Jelly
Grade	Outcome	Effect	Size	Studies	People
	Blood glucose Small Improvement	Improves (the measure goes down)	Small effect		71 people
	Blood Pressure No effect		NoneNo effect		56 people
	High-density lipoprotein (HDL)	Improves (the measure goes up)		1 study	71 people
Studies that measured high-density lipoprotein (hdl) Royal jelly supplementation improves lipoprotein metabolism in humansJ Nutr Sci Vitaminol · PMID 17934240
	Testosterone	Improves (the measure goes up)		1 study	56 people
Studies that measured testosterone Effect of royal jelly ingestion for six months on healthy volunteersNutr J · PMID 22995464
	Estrogen	Changes; see studies			56 people
	Glycemic Control	Improves (the measure goes up)			56 people
	HbA1c	Improves (the measure goes down)			56 people
	Liver Enzymes	Changes; see studies			15 people
	Low-density lipoprotein (LDL)	Improves (the measure goes down)			71 people
	Total cholesterol	Improves (the measure goes down)			15 people
	Triglycerides	Improves (the measure goes down)			71 people
	Weight	Improves (the measure goes down)			56 people

General Cardiovascular Health

General Cardiovascular Health: outcomes studied for Royal Jelly
Grade	Outcome	Effect	Size	Studies	People
	Blood glucose Small Improvement	Improves (the measure goes down)	Small effect		15 people
	High-density lipoprotein (HDL)	Improves (the measure goes up)		1 study	15 people
Studies that measured high-density lipoprotein (hdl) Royal jelly supplementation improves lipoprotein metabolism in humansJ Nutr Sci Vitaminol · PMID 17934240
	Liver Enzymes	Changes; see studies			15 people
	Low-density lipoprotein (LDL)	Improves (the measure goes down)			15 people
	Total cholesterol	Improves (the measure goes down)			15 people
	Triglycerides	Improves (the measure goes down)			15 people

Menopause

C-Reactive Protein (CRP)
High-density lipoprotein (HDL): improves
Irritability: improves

Menopause: outcomes studied for Royal Jelly
Grade	Outcome	Effect	Size	Studies	People
	C-Reactive Protein (CRP) No effect		NoneNo effect		55 people
	High-density lipoprotein (HDL)	Improves (the measure goes up)		1 study	55 people
Studies that measured high-density lipoprotein (hdl) Royal jelly supplementation improves lipoprotein metabolism in humansJ Nutr Sci Vitaminol · PMID 17934240
	Irritability	Improves (the measure goes down)		1 study	55 people
Studies that measured irritability Effects of an herbal medication containing bee products on menopausal symptoms and cardiovascular risk markers: results of a pilot open-uncontrolled trialMedGenMed · PMID 15775873
	Cell Adhesion Factors	Improves (the measure goes down)			55 people
	Depression Symptoms	Improves (the measure goes down)			55 people
	Low-density lipoprotein (LDL)	Improves (the measure goes down)			55 people
	Menopausal Symptoms	Improves (the measure goes down)			55 people
	Triglycerides	Improves (the measure goes down)			55 people

Allergic Rhinitis (Seasonal Allergies / Hay Fever)

Allergy Symptoms: improves

Allergic Rhinitis (Seasonal Allergies / Hay Fever): outcomes studied for Royal Jelly
Grade	Outcome	Effect	Size	Studies	People	Studies list
	Allergy Symptoms	Improves (the measure goes down)		1 study	64 people
Studies that measured allergy symptoms Double-blind randomized trial of the effect of Bidro on hay fever in childrenUgeskr Laeger · PMID 16219189

Premenstrual Syndrome (PMS)

PMS Symptoms: improves

Premenstrual Syndrome (PMS): outcomes studied for Royal Jelly
Grade	Outcome	Effect	Size	Studies	People	Studies list
	PMS Symptoms	Improves (the measure goes down)		1 study	110 people
Studies that measured pms symptoms Effect of Royal Jelly on premenstrual syndrome among Iranian medical sciences students: a randomized, triple-blind, placebo-controlled studyComplement Ther Med · PMID 25146061

Key findings

Blood glucoseMetabolic HealthImproves (the measure goes down)
Blood PressureMetabolic Health
C-Reactive Protein (CRP)Menopause

Shop Royal Jelly

Third-party tested Royal Jelly products. The evidence above is limited, so read it before you buy.

Grade C

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Studies cited

5 studies from PubMed

Effect of royal jelly ingestion for six months on healthy volunteersNutr J · PMID 22995464
Royal jelly supplementation improves lipoprotein metabolism in humansJ Nutr Sci Vitaminol · PMID 17934240
Effects of an herbal medication containing bee products on menopausal symptoms and cardiovascular risk markers: results of a pilot open-uncontrolled trialMedGenMed · PMID 15775873
Double-blind randomized trial of the effect of Bidro on hay fever in childrenUgeskr Laeger · PMID 16219189
Effect of Royal Jelly on premenstrual syndrome among Iranian medical sciences students: a randomized, triple-blind, placebo-controlled studyComplement Ther Med · PMID 25146061