Black seed
Black seed (Nigella sativa) is one of the most evidence-backed supplements in the database. A-GRADE for allergy symptoms (3 RCTs, 257 participants, moderate improvement). B-GRADE for blood glucose (29 RCTs, 3679 participants), blood pressure (22 RCTs, 1527 participants), and C-reactive protein (11 RCTs, 727 participants). Thymoquinone is the primary active compound. Traditional Islamic medicine ('the cure for everything except death'). Extensive human research supports benefits for metabolic and inflammatory conditions. Generally safe with few drug interactions.
Quick Answer
What it is
Black seed (Nigella sativa) is one of the most evidence-backed supplements in the database. A-GRADE for allergy symptoms (3 RCTs, 257 participants, moderate improvement).
Key findings
- Grade A: Allergy Symptoms (Allergic Rhinitis (Seasonal Allergies / Hay Fever))
- Grade B: Blood glucose
- Grade B: Blood Pressure
Safety
No specific caution or interaction language was detected in the current summary/outcome notes.
ℹ️ Quick Facts: Black seed
Quick Facts: Black seed
- Best Evidence:Grade A
- Conditions Studied:18
- Research Outcomes:111
- Grade A Findings:1
- Grade B Findings:7
- Key Effect:Allergic Rhinitis (Seasonal Allergies / Hay Fever)
Detailed Outcomes
Evidence by Condition
Best grade per condition (each condition may have multiple outcomes)
Research Citations (33)
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