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Terminalia Arjuna

Terminalia arjuna is a tree whose bark has long been used in Ayurvedic medicine, valued for plant compounds that may act as antioxidants. In people with coronary artery disease, heart size went down and the heart's pumping strength, measured as ejection fraction, improved, though the evidence is limited. Each finding came from a single study of just 10 people, and a review in stable angina found no clear difference in exercise tolerance.

Sources: PMID 9505018; PMID 7649665

Best evidence
Grade C
Conditions studied
10
Outcomes
17
Graded outcomes
0025

Evidence by condition

  • Strong
  • Moderate
  • Limited
  • Very limited

10 conditions

Coronary Artery Disease (CAD): outcomes studied for Terminalia Arjuna
GradeOutcomeEffectSizeStudiesPeopleStudies list
Heart Size

Small Decrease

Improves (the measure goes down)Small effect1 study10 people

Studies that measured heart size

Left Ventricular Ejection Fraction

Small Improvement

Improves (the measure goes up)Small effect1 study10 people

Studies that measured left ventricular ejection fraction

Liver EnzymesChanges; see studies10 people
Stable Angina: outcomes studied for Terminalia Arjuna
GradeOutcomeEffectSizeStudiesPeopleStudies list
Exercise Tolerance

No effect

NoneNo effect1 study133 people

Studies that measured exercise tolerance

ST-segment depressionImproves (the measure goes down)133 people

Aerobic Exercise Performance

  • Anaerobic Capacity
  • Power Output: improves
Aerobic Exercise Performance: outcomes studied for Terminalia Arjuna
GradeOutcomeEffectSizeStudiesPeopleStudies list
Anaerobic Capacity

No effect

NoneNo effect40 people
Power OutputImproves (the measure goes up)40 people

Muscle Size Strength

  • Anaerobic Capacity
  • Power Output: improves
Muscle Size Strength: outcomes studied for Terminalia Arjuna
GradeOutcomeEffectSizeStudiesPeopleStudies list
Anaerobic Capacity

No effect

NoneNo effect40 people
Power OutputImproves (the measure goes up)40 people

General Athletic Performance

  • Anaerobic Capacity
  • Power Output: improves
General Athletic Performance: outcomes studied for Terminalia Arjuna
GradeOutcomeEffectSizeStudiesPeopleStudies list
Anaerobic Capacity

No effect

NoneNo effect40 people
Power OutputImproves (the measure goes up)40 people

Muscle Size & Strength

  • Anaerobic Capacity
  • Power Output: improves
Muscle Size & Strength: outcomes studied for Terminalia Arjuna
GradeOutcomeEffectSizeStudiesPeopleStudies list
Anaerobic Capacity

No effect

NoneNo effect40 people
Power OutputImproves (the measure goes up)40 people

Cardiomyopathy

  • Left Ventricular Ejection Fraction: improves
Cardiomyopathy: outcomes studied for Terminalia Arjuna
GradeOutcomeEffectSizeStudiesPeopleStudies list
Left Ventricular Ejection FractionImproves (the measure goes up)1 study12 people

Studies that measured left ventricular ejection fraction

Heart Failure

  • Left Ventricular Ejection Fraction: improves
Heart Failure: outcomes studied for Terminalia Arjuna
GradeOutcomeEffectSizeStudiesPeopleStudies list
Left Ventricular Ejection FractionImproves (the measure goes up)1 study12 people

Studies that measured left ventricular ejection fraction

Ischemic Mitral Regurgitation

  • Mitral Regurgitation: improves
Ischemic Mitral Regurgitation: outcomes studied for Terminalia Arjuna
GradeOutcomeEffectSizeStudiesPeopleStudies list
Mitral RegurgitationImproves (the measure goes up)1 study40 people

Studies that measured mitral regurgitation

General Cardiovascular Health

  • Anaerobic Capacity: improves
General Cardiovascular Health: outcomes studied for Terminalia Arjuna
GradeOutcomeEffectSizeStudiesPeopleStudies list
Anaerobic CapacityImproves (the measure goes up)40 people

Key findings

  • Heart SizeCoronary Artery Disease (CAD)Improves (the measure goes down)
  • Left Ventricular Ejection FractionCoronary Artery Disease (CAD)Improves (the measure goes up)
  • Exercise ToleranceStable Angina

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  • Grade C

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Studies cited

5 studies from PubMed

  1. Effects of Withania somnifera (Ashwagandha) and Terminalia arjuna (Arjuna) on physical performance and cardiorespiratory endurance in healthy young adultsInt J Ayurveda Res · PMID 21170205
  2. Role of Terminalia arjuna in ischaemic mitral regurgitationInt J Cardiol · PMID 15837100
  3. Salutary effect of Terminalia Arjuna in patients with severe refractory heart failureInt J Cardiol · PMID 7649665
  4. Beneficial effects of Terminalia arjuna in coronary artery diseaseIndian Heart J · PMID 9505018
  5. Terminalia arjuna in Chronic Stable Angina: Systematic Review and Meta-Analysis.Cardiol Res Pract · PMID 24600529