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Terminalia arjuna is a tree whose bark has long been used in Ayurvedic medicine, valued for plant compounds that may act as antioxidants. In people with coronary artery disease, heart size went down and the heart's pumping strength, measured as ejection fraction, improved, though the evidence is limited. Each finding came from a single study of just 10 people, and a review in stable angina found no clear difference in exercise tolerance.
Sources: PMID 9505018; PMID 7649665
- Updated
- How we grade
- 5 studies cited
- Best evidence
- Grade C
- Conditions studied
- 10
- Outcomes
- 17
- Graded outcomes
- 0025
Evidence by condition
- Strong
- Moderate
- Limited
- Very limited
| Grade | Outcome | Effect | Size | Studies | People | Studies list |
|---|---|---|---|---|---|---|
| Heart Size Small Decrease | Improves (the measure goes down) | Small effect | 1 study | 10 people | ||
Studies that measured heart size | ||||||
| Left Ventricular Ejection Fraction Small Improvement | Improves (the measure goes up) | Small effect | 1 study | 10 people | ||
Studies that measured left ventricular ejection fraction | ||||||
| Liver Enzymes | Changes; see studies | 10 people | ||||
| Grade | Outcome | Effect | Size | Studies | People | Studies list |
|---|---|---|---|---|---|---|
| Exercise Tolerance No effect | NoneNo effect | 1 study | 133 people | |||
Studies that measured exercise tolerance | ||||||
| ST-segment depression | Improves (the measure goes down) | 133 people | ||||
Aerobic Exercise Performance
- Anaerobic Capacity
- Power Output: improves
| Grade | Outcome | Effect | Size | Studies | People | Studies list |
|---|---|---|---|---|---|---|
| Anaerobic Capacity No effect | NoneNo effect | 40 people | ||||
| Power Output | Improves (the measure goes up) | 40 people |
Muscle Size Strength
- Anaerobic Capacity
- Power Output: improves
| Grade | Outcome | Effect | Size | Studies | People | Studies list |
|---|---|---|---|---|---|---|
| Anaerobic Capacity No effect | NoneNo effect | 40 people | ||||
| Power Output | Improves (the measure goes up) | 40 people |
General Athletic Performance
- Anaerobic Capacity
- Power Output: improves
| Grade | Outcome | Effect | Size | Studies | People | Studies list |
|---|---|---|---|---|---|---|
| Anaerobic Capacity No effect | NoneNo effect | 40 people | ||||
| Power Output | Improves (the measure goes up) | 40 people |
Muscle Size & Strength
- Anaerobic Capacity
- Power Output: improves
| Grade | Outcome | Effect | Size | Studies | People | Studies list |
|---|---|---|---|---|---|---|
| Anaerobic Capacity No effect | NoneNo effect | 40 people | ||||
| Power Output | Improves (the measure goes up) | 40 people |
Cardiomyopathy
- Left Ventricular Ejection Fraction: improves
| Grade | Outcome | Effect | Size | Studies | People | Studies list |
|---|---|---|---|---|---|---|
| Left Ventricular Ejection Fraction | Improves (the measure goes up) | 1 study | 12 people | |||
Studies that measured left ventricular ejection fraction | ||||||
Heart Failure
- Left Ventricular Ejection Fraction: improves
| Grade | Outcome | Effect | Size | Studies | People | Studies list |
|---|---|---|---|---|---|---|
| Left Ventricular Ejection Fraction | Improves (the measure goes up) | 1 study | 12 people | |||
Studies that measured left ventricular ejection fraction | ||||||
Ischemic Mitral Regurgitation
- Mitral Regurgitation: improves
| Grade | Outcome | Effect | Size | Studies | People | Studies list |
|---|---|---|---|---|---|---|
| Mitral Regurgitation | Improves (the measure goes up) | 1 study | 40 people | |||
Studies that measured mitral regurgitation | ||||||
General Cardiovascular Health
- Anaerobic Capacity: improves
| Grade | Outcome | Effect | Size | Studies | People | Studies list |
|---|---|---|---|---|---|---|
| Anaerobic Capacity | Improves (the measure goes up) | 40 people |
Key findings
- Heart SizeImproves (the measure goes down)
- Left Ventricular Ejection FractionImproves (the measure goes up)
- Exercise Tolerance
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- Grade C
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Studies cited
5 studies from PubMed
- Effects of Withania somnifera (Ashwagandha) and Terminalia arjuna (Arjuna) on physical performance and cardiorespiratory endurance in healthy young adults
- Role of Terminalia arjuna in ischaemic mitral regurgitation
- Salutary effect of Terminalia Arjuna in patients with severe refractory heart failure
- Beneficial effects of Terminalia arjuna in coronary artery disease
- Terminalia arjuna in Chronic Stable Angina: Systematic Review and Meta-Analysis.