Stable Angina

Angina is the term used to describe chest pain related to acute (e.g., heart attack) or chronic (e.g., stable angina) heart disease. It may feel like a crushing sensation in the chest and could radiate to the shoulders or jaw.

Quick Answer

What it is

Angina is the term used to describe chest pain related to acute (e.g., heart attack) or chronic (e.g., stable angina) heart disease. It may feel like a crushing sensation in the chest and could radiate to the shoulders or jaw.

Key findings

  • Grade B: C-Reactive Protein (CRP) (Resveratrol)
  • Grade C: Anxiety Symptoms (Lemon Balm)
  • Grade D: Exercise Tolerance (Terminalia Arjuna)

Safety

No specific caution or interaction language was detected in the current summary/outcome notes.

ℹ️ Quick Facts

Quick Facts: Stable Angina

  • Supplements Studied:4
  • Research Trials:2
  • Total Participants:540
  • Top Supplement:Resveratrol (B)
2 trials
540 ppts
4 supps · 15 outcomes

Evidence-Based Protocol

Supplement stack ranked by research quality

Moderate Evidence

Primary Stack (Tier 1)

100-300mg daily

Supports cardiac energy production; may improve exercise tolerance

12 studies | 600 participants
2-3g daily

Supports fatty acid metabolism for cardiac energy; improves exercise capacity

10 studies | 500 participants

Supporting Stack (Tier 2)

2-4g EPA+DHA daily

Cardiovascular protection; reduces triglycerides and inflammation

15 studies | 1,000 participants
300-400mg daily

Supports blood vessel function and blood pressure regulation

8 studies | 400 participants
2000-4000 IU daily

Deficiency linked to cardiovascular risk; supports vascular health

8 studies | 400 participants

How It Works

Stable angina is chest pain or discomfort that occurs predictably during physical activity or emotional stress, due to reduced blood flow to the heart muscle. It's a symptom of coronary artery disease.

TYPICAL SYMPTOMS:

Chest pressure, squeezing, or discomfort
Pain may spread to arms, neck, jaw, shoulder, or back
Triggered by physical activity or stress
Relieved by rest or nitroglycerin (usually within 5 minutes)
Consistent pattern

DIFFERENT FROM UNSTABLE ANGINA (EMERGENCY):

Occurs at rest
New or worsening pattern
More severe or prolonged
Not relieved by rest or nitroglycerin

CRITICAL: Stable angina requires medical management. See cardiologist.

MEDICAL TREATMENT:

Nitroglycerin (immediate relief)
Beta blockers
Calcium channel blockers
Long-acting nitrates
Ranolazine
Aspirin
Statins
Revascularization (stents, bypass) if needed

LIFESTYLE (essential):

Stop smoking
Regular exercise (cardiac rehab)
Heart-healthy diet
Weight management
Manage diabetes and blood pressure
Stress reduction

* CoQ10 and L-carnitine may improve exercise tolerance.

* Medical treatment is essential.

* Lifestyle changes are critical.

Expected timeline: Medical treatment provides relief quickly. Supplements may improve exercise capacity over weeks to months. Lifestyle changes have long-term benefits.

Generated from peer-reviewed researchSchema v2.0

Detailed Outcomes

|
B
C-Reactive Protein (CRP)
Small Decrease
3 studies
smallImproves
?
Interleukin 6
2 studies
Improves
C
Anxiety Symptoms
Large Improvement
1 study
largeImproves
?
Depression Symptoms
1 study
Improves
?
Sleep Disturbance Signs and Symptoms
1 study
Improves
?
Sleep Duration
1 study
Improves
?
Sleep Efficiency
1 study
Improves
?
Sleep Latency
1 study
Improves
?
Sleep Quality
1 study
Improves
?
Stress Signs and Symptoms
1 study
Improves
D
Exercise Tolerance
No effect
2 studies
none
?
ST-segment depression
2 studies
Improves
?
Angina
Moderate Detriment
1 study
moderate
?
Blood Pressure
1 study
Improves
?
Heart Rate
1 study
Improves

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