Fibromyalgia
Fibromyalgia is a nonspecific pain disorder with currently unknown causes, although supplements are still being investigated for the purpose of reducing this pain.
Quick Answer
What it is
Fibromyalgia is a nonspecific pain disorder with currently unknown causes, although supplements are still being investigated for the purpose of reducing this pain.
Key findings
- Grade C: Anxiety Symptoms (Saffron)
- Grade C: Anti-Oxidant Enzyme Profile (Coenzyme Q10)
- Grade C: Fatigue Symptoms (D-Ribose)
Safety
No specific caution or interaction language was detected in the current summary/outcome notes.
ℹ️ Quick Facts
Quick Facts: Fibromyalgia
- Supplements Studied:12
- Research Trials:26
- Total Participants:2,185
- Top Supplement:Coenzyme Q10 (B)
Evidence-Based Protocol
Supplement stack ranked by research quality
Primary Stack (Tier 1)
Supports mitochondrial energy production and reduces oxidative stress associated with fibromyalgia
Reduces muscle tension, supports NMDA receptor regulation, and addresses common deficiency in FM patients
Supporting Stack (Tier 2)
How It Works
Fibromyalgia involves widespread pain, fatigue, and cognitive difficulties ("fibro fog"). The underlying mechanisms include central sensitization (the nervous system amplifying pain signals), mitochondrial dysfunction (reduced cellular energy production), and various nutritional deficiencies. This protocol addresses these root causes.
Expected timeline: CoQ10 and D-ribose may show energy improvements within 2-3 weeks, with pain reduction over 4-8 weeks. Magnesium effects begin within 1-2 weeks. Vitamin D requires 2-3 months to fully optimize levels.
Supplements for Fibromyalgia
Sorted by strength of evidence
Detailed Outcomes
Research Citations (5)
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