Lactobacillus reuteri

Lactobacillus reuteri is a bacterium with probiotic properties. Supplementation with L. reuteri seems to improve symptoms of infantile colic and could be beneficial in the management of a variety of gastrointestinal issues, including infectious diarrhea and H. pylori infection. Lactobacillus reuteri has been reclassified, resulting in a name change to Limosilactobacillus reuteri.

Quick Answer

What it is

Lactobacillus reuteri is a bacterium with probiotic properties. Supplementation with L.

Key findings

  • Grade B: Helicobacter Pylori Infection Signs (H. Pylori Infection)
  • Grade B: Infant crying
  • Grade B: Gastrointestinal symptoms

Safety

No specific caution or interaction language was detected in the current summary/outcome notes.

ℹ️ Quick Facts: Lactobacillus reuteri

Quick Facts: Lactobacillus reuteri

  • Best Evidence:Grade A
  • Conditions Studied:17
  • Research Outcomes:89
  • Grade B Findings:5
  • Key Effect:Acute Gastroenteritis
Outcomes by grade:
A0
B5
C5
D5
17 conditions Β· 89 outcomes

Detailed Outcomes

Grade:
Effect:
Size:
Sort:
|
B
Helicobacter Pylori Infection Signs
Small Improvement
small↑Improves
B
Gastrointestinal symptoms
Small Improvement
5 studies
small↓Improves
B
Infant crying
Moderate Improvement
moderate↑Improves
C
Constipation Signs and Symptoms
Small Improvement
1 study
small↓Improves
B
Gastrointestinal symptoms
Small Improvement
5 studies
small↓Improves
?
Helicobacter Pylori Infection Signs
↑Improves
B
Infant crying
Moderate Improvement
moderate↑Improves
C
Constipation Signs and Symptoms
Small Improvement
1 study
small↓Improves
C
Cystic Fibrosis Symptoms
Small Improvement
2 studies
small↓Improves
?
Interleukin 8
1 study
↑Worsens
?
Lung Function
↑Improves
?
TNF-Alpha
↓Improves
?
Upper Respiratory Tract Infection Risk
1 study
↑Worsens
C
Constipation Signs and Symptoms
Small Improvement
1 study
small↓Improves
?
Immunity
↑Improves
?
Infant crying
↑Improves
?
Interleukin 1-beta
1 study
↓Improves
?
Interleukin 10
1 study
↑Improves
?
Interleukin 6
1 study
↓Improves
?
Interleukin 8
1 study
↑Worsens
?
Lipid Absorption
1 study
↑Improves
?
Lung Function
↑Improves
?
Lymphocyte Count
1 study
↑Improves
?
Monocyte Count
1 study
↑Improves
?
TNF-Alpha
↓Improves
?
Weight
1 study
↓Improves
C
Constipation Signs and Symptoms
Small Improvement
1 study
small↓Improves
?
Fecal Weight
↓Improves
D
Blood glucose
No effect
8 studies
none
?
Blood Pressure
↓Improves
?
High-density lipoprotein (HDL)
7 studies
↑Improves
?
Low-density lipoprotein (LDL)
7 studies
↓Improves
?
Total cholesterol
7 studies
↓Improves
?
Triglycerides
↓Improves
D
Apolipoprotein A
No effect
1 study
none
?
Apolipoprotein B
↓Improves
?
High-density lipoprotein (HDL)
2 studies
↑Improves
?
Low-density lipoprotein (LDL)
2 studies
↓Improves
?
Total cholesterol
2 studies
↓Improves
?
Triglycerides
↓Improves
?
Bilirubin
1 study
↑Worsens
?
C-Reactive Protein (CRP)
1 study
↓Improves
?
Fecal Bile Acids
1 study
↑Improves
?
Fibrinogen
1 study
↑Improves
?
Kidney Function
1 study
↑Improves
?
Liver Enzymes
1 study
↑Worsens
?
Plasma Vitamin D
↑Improves
?
Plasma Vitamin E
1 study
↑Improves
?
Plasma Ξ²-carotene
1 study
↑Improves
D
B Cell Count
No effect
1 study
none
?
Immunity
↑Improves
?
Immunoglobulin A
↑Improves
?
Lymphocyte Count
1 study
↑Improves
?
Monocyte Count
1 study
↑Improves
D
Bilirubin
No effect
1 study
none
?
Blood Pressure
↓Improves
?
Heart Rate
↓Improves
?
High-density lipoprotein (HDL)
1 study
↑Improves
?
Kidney Function
1 study
↑Improves
?
Liver Enzymes
1 study
↑Worsens
?
Low-density lipoprotein (LDL)
1 study
↓Improves
?
Lymphocyte Count
1 study
↑Improves
?
Monocyte Count
1 study
↑Improves
?
Neutrophil Count
1 study
↑Improves
?
Red Blood Cell Count
1 study
↑Improves
?
Serum Platelets
1 study
↑Improves
?
Total cholesterol
1 study
↓Improves
?
Triglycerides
↓Improves
?
Weight
1 study
↓Improves
?
White Blood Cell Count
1 study
↑Improves
D
Bilirubin
No effect
1 study
none
?
Blood glucose
1 study
↓Improves
?
Blood Pressure
↓Improves
?
Heart Rate
↓Improves
?
Hematocrit
1 study
↑Improves
?
Hemoglobin
1 study
↑Improves
?
Liver Enzymes
1 study
↑Worsens
?
Low-density lipoprotein (LDL)
1 study
↓Improves
?
Weight
1 study
↓Improves
?
White Blood Cell Count
1 study
↑Improves
?
Diarrhea Symptoms
↓Improves
?
Abdominal Pain
↓Improves
?
Dental Health Metrics
↑Improves
?
Depression Symptoms
↓Improves
?
Diarrhea Symptoms
↓Improves
?
Allergic Disease Risk
↑Worsens
?
Allergic Disease Risk
↑Worsens
?
Diarrhea Symptoms
↓Improves
?
Immunoglobulin A
↑Improves

Research Citations (30)

Evaluation of clinical safety and tolerance of a Lactobacillus reuteri NCIMB 30242 supplement capsule: a randomized control trial
PMID: 22561556
Cholesterol-lowering efficacy of a microencapsulated bile salt hydrolase-active Lactobacillus reuteri NCIMB 30242 yoghurt formulation in hypercholesterolaemic adults
PMID: 22067612
Cholesterol lowering and inhibition of sterol absorption by Lactobacillus reuteri NCIMB 30242: a randomized controlled trial
PMID: 22990854
Oral supplementation with probiotic L. reuteri NCIMB 30242 increases mean circulating 25-hydroxyvitamin D: a post hoc analysis of a randomized controlled trial
PMID: 23609838
Safety and tolerance of Lactobacillus reuteri supplementation to a population infected with the human immunodeficiency virus
PMID: 9862651
Probiotics for infantile colic: Is there evidence beyond doubt? A meta-analysis and systematic review.
PMID: 37962097
Probiotics to prevent or treat excessive infant crying: systematic review and meta-analysis
PMID: 24100440
Treating infant colic with the probiotic Lactobacillus reuteri: double blind, placebo controlled randomised trial
PMID: 24690625
Lactobacillus reuteri DSM 17938 in infantile colic: a randomized, double-blind, placebo-controlled trial
PMID: 20713478
Prophylactic use of a probiotic in the prevention of colic, regurgitation, and functional constipation: a randomized clinical trial
PMID: 24424513

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