Skip to content
Dr. Grey AI

Condition

Peri-implant diseases

Peri-implant diseases are conditions affecting the gum and bone tissue around dental implants, much like gum disease affects natural teeth, and they involve inflammation driven by bacteria that can wear down the supporting bone. Vitamin D and calcium have been looked at most, because of their role in bone health, but little research on them has been reviewed here so far. Omega-3s and probiotics are also being explored, though the evidence for all four is limited.

Supplements studied
1
Graded outcomes
0
People studied
196

Evidence by supplement

  • Strong
  • Moderate
  • Limited
  • Very limited

1 supplement

Lactobacillus reuteri: outcomes studied for Peri-implant diseases
GradeOutcomeEffectSizeStudiesPeopleStudies list
Dental Health MetricsImproves (the measure goes up)1 study196 people

The Peri-implant Disease Support protocol

2 primary supplements · 2 supporting supplements

See the full protocol

Studies cited

30 studies from PubMed

  1. Evaluation of clinical safety and tolerance of a Lactobacillus reuteri NCIMB 30242 supplement capsule: a randomized control trialRegul Toxicol Pharmacol · PMID 22561556
  2. Cholesterol-lowering efficacy of a microencapsulated bile salt hydrolase-active Lactobacillus reuteri NCIMB 30242 yoghurt formulation in hypercholesterolaemic adultsBr J Nutr · PMID 22067612
  3. Cholesterol lowering and inhibition of sterol absorption by Lactobacillus reuteri NCIMB 30242: a randomized controlled trialEur J Clin Nutr · PMID 22990854
  4. Oral supplementation with probiotic L. reuteri NCIMB 30242 increases mean circulating 25-hydroxyvitamin D: a post hoc analysis of a randomized controlled trialJ Clin Endocrinol Metab · PMID 23609838
  5. Safety and tolerance of Lactobacillus reuteri supplementation to a population infected with the human immunodeficiency virusFood Chem Toxicol · PMID 9862651
  6. Probiotics for infantile colic: Is there evidence beyond doubt? A meta-analysis and systematic review.Acta Paediatr · PMID 37962097
  7. Probiotics to prevent or treat excessive infant crying: systematic review and meta-analysisJAMA Pediatr · PMID 24100440
  8. Treating infant colic with the probiotic Lactobacillus reuteri: double blind, placebo controlled randomised trialBMJ · PMID 24690625
  9. Lactobacillus reuteri DSM 17938 in infantile colic: a randomized, double-blind, placebo-controlled trialPediatrics · PMID 20713478
  10. Prophylactic use of a probiotic in the prevention of colic, regurgitation, and functional constipation: a randomized clinical trialJAMA Pediatr · PMID 24424513
  11. Lactobacillus reuteri (American Type Culture Collection Strain 55730) versus simethicone in the treatment of infantile colic: a prospective randomized studyPediatrics · PMID 17200238
  12. 454 pyrosequencing analysis on faecal samples from a randomized DBPC trial of colicky infants treated with Lactobacillus reuteri DSM 17938PLoS One · PMID 23468874
  13. Lactobacillus reuteri DSM 17938 for the management of infantile colic in breastfed infants: a randomized, double-blind, placebo-controlled trialJ Pediatr · PMID 22981952
  14. Improvement of digestive health and reduction in proteobacterial populations in the gut microbiota of cystic fibrosis patients using a Lactobacillus reuteri probiotic preparation: a double blind prospective studyJ Cyst Fibros · PMID 24636808
  15. Safety and tolerability of Lactobacillus reuteri DSM 17938 and effects on biomarkers in healthy adults: results from a randomized masked trialPLoS One · PMID 22970150
  16. Salivary IgA response to probiotic bacteria and mutans streptococci after the use of chewing gum containing Lactobacillus reuteriPathog Dis · PMID 23737255
  17. Lactobacillus reuteri ATCC55730 in cystic fibrosisJ Pediatr Gastroenterol Nutr · PMID 24121143
  18. A randomized, double-blind, placebo-controlled pilot study of Lactobacillus reuteri ATCC 55730 for the prevention of antibiotic-associated diarrhea in hospitalized adultsJ Clin Gastroenterol · PMID 21552138
  19. No effect of probiotics on respiratory allergies: a seven-year follow-up of a randomized controlled trial in infancyPediatr Allergy Immunol · PMID 23902407
  20. Lactobacillus reuteri (DSM 17938) in infants with functional chronic constipation: a double-blind, randomized, placebo-controlled studyJ Pediatr · PMID 20542295
  21. Lactobacillus reuteri compared with placebo as an adjuvant in Helicobacter pylori eradication therapy: a meta-analysis of randomized controlled trials.Therap Adv Gastroenterol · PMID 38846173
  22. Inhibition of Helicobacter pylori infection in humans by Lactobacillus reuteri ATCC 55730 and effect on eradication therapy: a pilot studyHelicobacter · PMID 18321302
  23. Non-viable Lactobacillus reuteri DSMZ 17648 (Pylopass™) as a new approach to Helicobacter pylori control in humansNutrients · PMID 23917169
  24. The efficacy and acceptability of Lactobacillus reuteri for the treatment of depression: A systematic review and meta-analysis.Gen Hosp Psychiatry · PMID 40339531
  25. Probiotics for treating acute infectious diarrhoea.Cochrane Database Syst Rev · PMID 33295643
  26. The influence of probiotics on gastrointestinal tract infections among children attending childcare: A systematic review and meta-analysisJ Appl Microbiol · PMID 34796583
  27. A systematic review and meta-analysis: the therapeutic and preventive effect of Lactobacillus reuteri DSM 17,938 addition in children with diarrhea.BMC Gastroenterol · PMID 37147591
  28. Use of probiotics in the treatment of functional abdominal pain in children-systematic review and meta-analysisEur J Pediatr · PMID 32940743
  29. Limosilactobacillus reuteri consumption significantly reduces the total cholesterol concentration without affecting other cardiovascular disease risk factors in adults: A systematic review and meta-analysis.Nutr Res · PMID 37419064
  30. Adjunctive benefit of probiotic supplementation along with nonsurgical therapy for peri-implant diseases - A systematic review and meta-analysis.J Indian Soc Periodontol · PMID 37593565