Vinpocetine
Vinpocetine is a synthetic derivative of vincamine from the periwinkle plant, used in Europe as a prescription drug for cerebrovascular disorders. C-grade evidence for cognitive improvement in cerebrovascular insufficiency and dementia. Increases cerebral blood flow and has neuroprotective properties. Generally well-tolerated. Commonly used nootropic but evidence for memory enhancement in healthy individuals is limited. FDA has warned against use during pregnancy (potential fetal harm).
Quick Answer
What it is
Vinpocetine is a synthetic derivative of vincamine from the periwinkle plant, used in Europe as a prescription drug for cerebrovascular disorders. C-grade evidence for cognitive improvement in cerebrovascular insufficiency and dementia.
Key findings
- Grade C: Cognitive Decline (Chronic Cerebrovascular Insufficiency)
- Grade C: Functionality in Elderly (Chronic Cerebrovascular Insufficiency)
- Grade C: Memory (Cognitive Improvement)
Safety
No specific caution or interaction language was detected in the current summary/outcome notes.
ℹ️ Quick Facts: Vinpocetine
Quick Facts: Vinpocetine
- Best Evidence:Grade C
- Conditions Studied:3
- Research Outcomes:9
- Key Effect:Chronic Cerebrovascular Insufficiency
Detailed Outcomes
Evidence by Condition
Best grade per condition (each condition may have multiple outcomes)
Research Citations (3)
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