Supplement

Green Coffee Extract

Green coffee extract comes from unroasted coffee beans and is rich in chlorogenic acids, plant compounds that may influence how the body handles sugar and fat. The evidence is moderate for blood glucose, which improved in research involving 405 people, and a small trial also found better homocysteine levels. Even so, most studies were small, evidence for blood pressure and body fat is limited, and body mass index showed no clear difference in 1,721 people.

Sources: PMID 15785008

Updated 30 September 2026
How we grade
7 studies cited

Best evidence: Grade B
Conditions studied: 8
Outcomes: 32
Graded outcomes: 0141

Evidence by condition

Strong
Moderate
Limited
Very limited

8 conditions

Cardiovascular Disease

Cardiovascular Disease: outcomes studied for Green Coffee Extract
Grade	Outcome	Effect	Size	Studies	People
	Blood glucose Small Improvement	Improves (the measure goes down)	Small effect		405 people
	Weight	Improves (the measure goes down)		2 studies	532 people
Studies that measured weight The effect of green coffee extract supplementation on obesity indices: critical umbrella review of interventional meta-analyses.Crit Rev Food Sci Nutr · PMID 37341701 Chlorogenic acid in green bean coffee on body weight: a systematic review and meta-analysis of randomized controlled trials.Syst Rev · PMID 37710316
	Total cholesterol	Improves (the measure goes down)		1 study	578 people
Studies that measured total cholesterol The Effect of Green Coffee Bean Extract on Cardiovascular Risk Factors: A Systematic Review and Meta-analysis.Adv Exp Med Biol · PMID 34981487
	Blood Pressure	Improves (the measure goes down)			421 people
	Body Mass Index (BMI)	Improves (the measure goes down)			526 people
	HbA1c	Improves (the measure goes down)			122 people
	Insulin Resistance	Improves (the measure goes down)			199 people
	Low-density lipoprotein (LDL)	Improves (the measure goes down)			558 people
	Triglycerides	Improves (the measure goes down)			637 people
	Waist circumference	Improves (the measure goes down)			177 people

General Cardiovascular Health

General Cardiovascular Health: outcomes studied for Green Coffee Extract
Grade	Outcome	Effect	Size	Studies	People
	Homocysteine Small Improvement	Improves (the measure goes down)	Small effect	1 study	20 people
Studies that measured homocysteine Green coffee bean extract improves human vasoreactivityHypertens Res · PMID 15785008
	Vascular Function	Improves (the measure goes up)			20 people

High Blood Pressure

Blood glucose: improves
Blood Pressure: improves
Weight: improves

High Blood Pressure: outcomes studied for Green Coffee Extract
Grade	Outcome	Effect	Size	Studies	People
	Blood glucose Small Improvement	Improves (the measure goes down)	Small effect		28 people
	Blood Pressure Moderate Improvement	Improves (the measure goes down)	Moderate effect		28 people
	Weight	Improves (the measure goes down)		2 studies	28 people
Studies that measured weight The effect of green coffee extract supplementation on obesity indices: critical umbrella review of interventional meta-analyses.Crit Rev Food Sci Nutr · PMID 37341701 Chlorogenic acid in green bean coffee on body weight: a systematic review and meta-analysis of randomized controlled trials.Syst Rev · PMID 37710316
	C-Reactive Protein (CRP)	Improves (the measure goes down)		1 study	265 people
Studies that measured c-reactive protein (crp) Effects of green coffee bean extract on C-reactive protein levels: A systematic review and meta-analysis of randomized controlled trials.Complement Ther Med · PMID 32951749
	Total cholesterol	Improves (the measure goes down)		1 study	28 people
Studies that measured total cholesterol The Effect of Green Coffee Bean Extract on Cardiovascular Risk Factors: A Systematic Review and Meta-analysis.Adv Exp Med Biol · PMID 34981487
	Heart Rate	Improves (the measure goes down)			28 people
	High-density lipoprotein (HDL)	Improves (the measure goes up)			28 people
	Kidney Function	Improves (the measure goes up)			28 people
	Liver Enzymes	Changes; see studies			28 people
	Low-density lipoprotein (LDL)	Improves (the measure goes down)			28 people
	Triglycerides	Improves (the measure goes down)			28 people
	White Blood Cell Count	Improves (the measure goes up)			28 people

Metabolic Health

Body Fat: improves
Weight: improves

Metabolic Health: outcomes studied for Green Coffee Extract
Grade	Outcome	Effect	Size	Studies	People
	Body Fat Small Decrease	Improves (the measure goes down)	Small effect		30 people
	Weight	Improves (the measure goes down)		2 studies	30 people
Studies that measured weight The effect of green coffee extract supplementation on obesity indices: critical umbrella review of interventional meta-analyses.Crit Rev Food Sci Nutr · PMID 37341701 Chlorogenic acid in green bean coffee on body weight: a systematic review and meta-analysis of randomized controlled trials.Syst Rev · PMID 37710316

Obesity

Body Mass Index (BMI)
Weight: improves
Waist circumference: improves

Obesity: outcomes studied for Green Coffee Extract
Grade	Outcome	Effect	Size	Studies	People
	Body Mass Index (BMI) No effect		NoneNo effect		1,721 people
	Weight	Improves (the measure goes down)		2 studies	1,989 people
Studies that measured weight The effect of green coffee extract supplementation on obesity indices: critical umbrella review of interventional meta-analyses.Crit Rev Food Sci Nutr · PMID 37341701 Chlorogenic acid in green bean coffee on body weight: a systematic review and meta-analysis of randomized controlled trials.Syst Rev · PMID 37710316
	Waist circumference	Improves (the measure goes down)			2,117 people

Weight Loss & Maintenance

Weight: improves

Weight Loss & Maintenance: outcomes studied for Green Coffee Extract
Grade	Outcome	Effect	Size	Studies	People	Studies list
	Weight	Improves (the measure goes down)		2 studies	103 people
Studies that measured weight The effect of green coffee extract supplementation on obesity indices: critical umbrella review of interventional meta-analyses.Crit Rev Food Sci Nutr · PMID 37341701 Chlorogenic acid in green bean coffee on body weight: a systematic review and meta-analysis of randomized controlled trials.Syst Rev · PMID 37710316

Nonalcoholic Fatty Liver Disease (NAFLD)

C-Reactive Protein (CRP): improves

Nonalcoholic Fatty Liver Disease (NAFLD): outcomes studied for Green Coffee Extract
Grade	Outcome	Effect	Size	Studies	People	Studies list
	C-Reactive Protein (CRP)	Improves (the measure goes down)		1 study	265 people
Studies that measured c-reactive protein (crp) Effects of green coffee bean extract on C-reactive protein levels: A systematic review and meta-analysis of randomized controlled trials.Complement Ther Med · PMID 32951749

Dyslipidemia

C-Reactive Protein (CRP): improves

Dyslipidemia: outcomes studied for Green Coffee Extract
Grade	Outcome	Effect	Size	Studies	People	Studies list
	C-Reactive Protein (CRP)	Improves (the measure goes down)		1 study	265 people
Studies that measured c-reactive protein (crp) Effects of green coffee bean extract on C-reactive protein levels: A systematic review and meta-analysis of randomized controlled trials.Complement Ther Med · PMID 32951749

Key findings

Blood glucoseCardiovascular DiseaseImproves (the measure goes down)
HomocysteineImproves (the measure goes down)
Blood PressureHigh Blood PressureImproves (the measure goes down)

Shop the evidence-backed picks

Third-party tested Green Coffee Extract products, in the forms the graded studies used where we can match them.

Grade B

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Studies cited

7 studies from PubMed

The blood pressure-lowering effect and safety of chlorogenic acid from green coffee bean extract in essential hypertensionClin Exp Hypertens · PMID 16820341
The effect of chlorogenic acid enriched coffee on glucose absorption in healthy volunteers and its effect on body mass when used long-term in overweight and obese peopleJ Int Med Res · PMID 18035001
Effects of green coffee bean extract on C-reactive protein levels: A systematic review and meta-analysis of randomized controlled trials.Complement Ther Med · PMID 32951749
Green coffee bean extract improves human vasoreactivityHypertens Res · PMID 15785008
The Effect of Green Coffee Bean Extract on Cardiovascular Risk Factors: A Systematic Review and Meta-analysis.Adv Exp Med Biol · PMID 34981487
The effect of green coffee extract supplementation on obesity indices: critical umbrella review of interventional meta-analyses.Crit Rev Food Sci Nutr · PMID 37341701
Chlorogenic acid in green bean coffee on body weight: a systematic review and meta-analysis of randomized controlled trials.Syst Rev · PMID 37710316