Crohn's Disease
Crohn’s disease is an inflammatory bowel disease. It differs from ulcerative colitis in three major ways: it can occur anywhere from the mouth to the anus; it usually exhibits patches of inflammation; it can affect multiple layers of tissue.
Quick Answer
What it is
Crohn’s disease is an inflammatory bowel disease. It differs from ulcerative colitis in three major ways: it can occur anywhere from the mouth to the anus; it usually exhibits patches of inflammation; it can affect multiple layers of tissue.
Key findings
- Grade D: Crohn's Disease Symptoms (Glutamine)
- Grade D: C-Reactive Protein (CRP) (Cannabis)
- Grade N/A: Hematocrit (Cannabis)
Safety
No specific caution or interaction language was detected in the current summary/outcome notes.
ℹ️ Quick Facts
Quick Facts: Crohn's Disease
- Supplements Studied:6
- Research Trials:9
- Total Participants:520
- Top Supplement:Glutamine (D)
Evidence-Based Protocol
Supplement stack ranked by research quality
Primary Stack (Tier 1)
Deficiency very common; supports immune modulation and bone health
Anti-inflammatory; may help maintain remission
Supporting Stack (Tier 2)
May help with gut microbiome balance; evidence mixed for Crohn's specifically
Anemia common due to blood loss and malabsorption
Deficiency common with ileal disease or resection
Deficiency common; supports immune function and wound healing
How It Works
Crohn's disease is a type of inflammatory bowel disease (IBD) that can affect any part of the digestive tract, most commonly the end of the small intestine (ileum) and beginning of the colon.
KEY FEATURES:
SYMPTOMS:
NUTRITIONAL DEFICIENCIES (common):
MEDICAL TREATMENTS:
NUTRITION:
* Vitamin D deficiency is very common - check and correct.
* B12 monitoring especially with ileal involvement.
* Work with GI specialist for medical management.
Expected timeline: Disease requires lifelong management. Supplements address deficiencies and may provide modest supportive benefit.
Supplements for Crohn's Disease
Sorted by strength of evidence
Detailed Outcomes
Research Citations (3)
Related Conditions
Metabolic Health
5 shared supplements · 975 outcomes
Research on metabolism, blood glucose regulation, insulin sensitivity, and metabolic syndrome.
Weight Loss & Maintenance
4 shared supplements · 433 outcomes
This goal refers to people with a BMI >25 attempting to reach/maintain their ideal weight. While interventions that work for people with a BMI >25 may also work for people with a lower BMI, the context is often sufficiently different that this isn't assured.
Type 2 Diabetes
4 shared supplements · 868 outcomes
Type 2 diabetes (T2D) is a disease in which blood glucose levels are too high. It is characterized by insulin resistance in muscle, fat, and pancreas cells and an inability of the pancreas to manufacture enough insulin to control blood glucose levels. T2D is strongly associated with excess body fat, and weight loss induced by lifestyle changes is extremely effective for treating T2D.
4 shared supplements · outcomes
Muscle Size & Strength
4 shared supplements · 334 outcomes
This page on muscle size and strength covers strategies to maximize muscle gain and strength gain. There is notable overlap in nutrition and supplementation strategies to facilitate these two goals, but there is some divergence in the best type of exercise. A larger muscle tends to be a stronger muscle.
Menopause
4 shared supplements · 223 outcomes
Menopause is the stage of life when menses permanently cease, and the reproductive system no longer performs functions related to fertility. A woman is considered to have entered menopause after menses have stopped for 12 months.
4 shared supplements · outcomes
General Athletic Performance
4 shared supplements · 656 outcomes
General athletic performance refers to an individual's ability to perform in various sports and physical activities, including strength, speed, endurance, and agility.