Vitamin B12
Vitamin B12 is an essential water-soluble vitamin that plays a role in neurological function and is important for DNA synthesis.
Quick Answer
What it is
Vitamin B12 is an essential water-soluble vitamin that plays a role in neurological function and is important for DNA synthesis.
Key findings
- Grade D: Cognition (Depression)
- Grade D: Depression Symptoms (Depression)
- Grade N/A: Fatigue Symptoms (Depression)
Safety
No specific caution or interaction language was detected in the current summary/outcome notes.
ℹ️ Quick Facts: Vitamin B12
Quick Facts: Vitamin B12
- Best Evidence:Grade D
- Conditions Studied:5
- Research Outcomes:18
- Key Effect:Depression
Detailed Outcomes
Evidence by Condition
Best grade per condition (each condition may have multiple outcomes)
Research Citations (5)
Related Supplements
Ginkgo Biloba
5 shared conditions · 173 outcomes
Ginkgo biloba is the most commonly ingested herb for brain health. While it may boost cognition in older populations, this effect is not very reliable or generalizable.
Fish Oil
5 shared conditions · 448 outcomes
Fish oil is a mix of mostly EPA and DHA derived from fatty fish. It reduces triglycerides, but does not seem to affect the rate of cardiovascular events. It appears to reduce the symptoms of depression and improve some painful, inflammatory conditions.
Saffron
3 shared conditions · 390 outcomes
Saffron is a spice with antioxidant properties derived from the flowering plant Crocus sativus. When used as a supplement, saffron seems to be effective at reducing symptoms of depression and possibly anxiety.
Piracetam
3 shared conditions · 15 outcomes
Piracetam is the parent compound of the racetam class of nootropic supplements. When supplemented, it provides a mild boost to brain function.
Folic Acid (Vitamin B9)
3 shared conditions · 45 outcomes
Folic acid is a synthetic form of folate, an essential B vitamin, found in dietary supplements and fortified foods. Folic acid reduces the risk of neural tube defects (NTDs) when used in early pregnancy, treats certain types of anemia, and reduces levels of homocysteine, the latter of which may be linked to beneficial cardiovascular effects.
Curcumin
3 shared conditions · 502 outcomes
Curcumin is the primary bioactive substance in turmeric. It has anti-inflammatory properties and can alleviate symptoms of depression as well as improve pain and function in people with osteoarthritis.
Zinc
2 shared conditions · 148 outcomes
Zinc is an essential mineral that is critical for the function of hundreds of enzymes. Consequently, it plays many roles, including in antioxidant enzymes, brain function, and the immune system. Zinc is most commonly taken to reduce the duration of respiratory infections and the common cold.
Theanine
2 shared conditions · 155 outcomes
Theanine, also commonly referred to as L-theanine, is a naturally occurring amino acid found in tea. Supplementation with L-theanine may help reduce stress and anxiety and might improve sleep quality and some aspects of cognitive function.