Supplement
Triphala is a traditional Ayurvedic blend of three fruits, amla and two myrobalans, whose plant compounds have a gentle laxative effect and support the gut. People mostly look at it for constipation-predominant irritable bowel syndrome, and the evidence for that use is limited. Trials in constipation more broadly found bowel movements became more frequent within a couple of weeks, but those studies were short, so they say little about long-term use.
- Updated
- How we grade
- 10 studies cited
- Best evidence
- Grade A
- Conditions studied
- 6
- Outcomes
- 7
- Graded outcomes
- 3400
Evidence by condition
- Strong
- Moderate
- Limited
- Very limited
| Grade | Outcome | Effect | Size | Studies | People | Studies list |
|---|---|---|---|---|---|---|
| Weight Loss Meta-analysis (7 trials, n=458): Triphala significantly reduced body weight (WMD -2.99 kg, 95% CI -5.31 to -0.67, p=0.012), BMI (WMD -0.79 kg/m2, p=0.032), and waist circumference. 12-week RCT: Triphala group lost approximately 5 kg vs placebo. Systematic review (5 RCTs): Statistically significant decreases in body weight, BMI, and waist circumference. | Improves (the measure goes down) | Moderate effect |
| Grade | Outcome | Effect | Size | Studies | People | Studies list |
|---|---|---|---|---|---|---|
| Lipid Profile Improvement Systematic review (12 studies, n=749): Six studies showed significant reductions in LDL-cholesterol, total cholesterol, and triglycerides. 12-month trial in T2DM patients: Triphala 5g twice daily significantly reduced lipid levels (p<0.05). Mechanism involves inhibition of HMG-CoA reductase and enhancement of bile acid excretion. | Improves (the measure goes down) | Moderate effect |
General Oral Health
- Gingivitis and Plaque Reduction: improves
| Grade | Outcome | Effect | Size | Studies | People | Studies list |
|---|---|---|---|---|---|---|
| Gingivitis and Plaque Reduction Meta-analysis (7 RCTs): Triphala mouthwash as effective as 0.2% chlorhexidine for plaque-induced gingivitis. RCT (n=90, 60 days): Significant reductions in plaque index, gingival index, and oral hygiene index scores. Triphala superior to aloe vera and equal to chlorhexidine with fewer side effects. Cost-effective alternative with no staining or taste alteration. | Improves (the measure goes down) | Large effect |
Type 2 Diabetes
- Blood Glucose Reduction: improves
| Grade | Outcome | Effect | Size | Studies | People | Studies list |
|---|---|---|---|---|---|---|
| Blood Glucose Reduction Systematic review: Triphala significantly decreased fasting blood glucose in diabetic patients. 12-month trial (n=50): Triphala 5g twice daily significantly reduced blood glucose (p<0.001). 45-day study: Both fasting and postprandial blood glucose reduced. Mechanism via alpha-amylase and alpha-glucosidase inhibition. | Improves (the measure goes down) | Moderate effect |
Digestive Health
- Constipation Relief: improves
- Gut Microbiome Modulation: improves
| Grade | Outcome | Effect | Size | Studies | People | Studies list |
|---|---|---|---|---|---|---|
| Constipation Relief Clinical trial: 1 week treatment increased average weekly bowel frequency by 64.4%, and by 79.5% after 2 weeks. RCT: Triphala churna (3-6g at night with warm water) showed significant improvement in bowel parameters. Mild laxative effect without causing dependence, strengthens bowel musculature. | Improves (the measure goes up) | Moderate effect | ||||
| Gut Microbiome Modulation Double-blind RCT (PMID 32955913): Triphala supplementation showed trend toward decreased Firmicutes/Bacteroidetes ratio and increased Akkermansia muciniphila. Enhanced growth of beneficial Bifidobacteria and Lactobacillus while reducing harmful species. Increased short-chain fatty acid production, particularly butyrate. | Improves (the measure goes up) | Small effect |
Immune Health
- Antioxidant Status: improves
| Grade | Outcome | Effect | Size | Studies | People | Studies list |
|---|---|---|---|---|---|---|
| Antioxidant Status Phase I clinical study in healthy volunteers: Triphala supplementation significantly increased SOD activity and decreased MDA and protein carbonyl concentrations. Rich in vitamin C, gallic acid, ellagic acid, and flavonoids. Free radical-scavenging activity comparable to ascorbic acid. | Improves (the measure goes up) | Moderate effect |
Key findings
- Weight LossImproves (the measure goes down)
- Lipid Profile ImprovementImproves (the measure goes down)
- Gingivitis and Plaque ReductionImproves (the measure goes down)
Shop the evidence-backed picks
Third-party tested Triphala (Emblica officinalis, Terminalia chebula, Terminalia bellirica) products, in the forms the graded studies used where we can match them.
- Grade A
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Studies cited
10 studies from PubMed
- Effects of Triphala on Lipid and Glucose Profiles and Anthropometric Parameters: A Systematic Review
- Effect of triphala mouthrinse on plaque and gingival inflammation: A systematic review and meta-analysis of randomized controlled trials
- Modulatory Effects of Triphala and Manjistha Dietary Supplementation on Human Gut Microbiota: A Double-Blind, Randomized, Placebo-Controlled Pilot Study
- A novel polyphenolic prebiotic and probiotic formulation have synergistic effects on the gut microbiota influencing Drosophila melanogaster physiology
- Therapeutic Uses of Triphala in Ayurvedic Medicine
- Comparative Evaluation of Triphala and Ela Decoction With 0.2% Chlorhexidine as Mouthwash in the Treatment of Plaque-Induced Gingivitis and Halitosis: A Randomized Controlled Clinical Trial
- Triphala, a New Herbal Mouthwash for the Treatment of Gingivitis: A Randomized Controlled Clinical Trial
- A randomized clinical trial to evaluate and compare the efficacy of triphala mouthwash with 0.2% chlorhexidine in hospitalized patients with periodontal diseases
- Efficacy of 'Itrifal Saghir', a combination of three medicinal plants in the treatment of obesity; A randomized controlled trial
- Triphala and its constituents ameliorate visceral adiposity from a high-fat diet in mice with diet-induced obesity