Dr. Grey AI

Serrapeptase

Serrapeptase is an enzyme derived from silkworms. It has anti-inflammatory effects and can help prevent blood clots, but these effects are somewhat unreliable.

Quick Answer

What it is

Serrapeptase is an enzyme derived from silkworms. It has anti-inflammatory effects and can help prevent blood clots, but these effects are somewhat unreliable.

Key findings

  • Grade B: Inflammation (Surgical Recovery)
  • Grade B: Leg Edema (Surgical Recovery)
  • Grade C: Mucus Production (Allergic Rhinitis (Seasonal Allergies / Hay Fever))

Safety

No specific caution or interaction language was detected in the current summary/outcome notes.

ℹ️ Quick Facts: Serrapeptase

Quick Facts: Serrapeptase

  • Best Evidence:Grade B
  • Conditions Studied:11
  • Research Outcomes:19
  • Grade B Findings:2
  • Key Effect:Surgical Recovery
Outcomes by grade:
A0
B2
C6
D0
11 conditions · 19 outcomes

Detailed Outcomes

Grade:
Effect:
Size:
Sort:
|
B
Inflammation
Small Decrease
small↓Improves
B
Leg Edema
Small Improvement
2 studies
small↓Improves
?
Pain
↓Improves
C
Mucus Production
Moderate Improvement
moderate↑Improves
?
Pain
↓Improves
C
Breast Tenderness
Small Improvement
1 study
small↓Improves
?
Pain
↓Improves
C
Pain
Small Improvement
small↓Improves
?
Superficial Thrombophlebitis Symptoms
↓Improves
C
Breast Tenderness
Small Improvement
1 study
small↓Improves
?
Pain
↓Improves
C
Inflammation
Small Decrease
small↓Improves
?
Pain
↓Improves
C
Inflammation
Small Decrease
small↓Improves
?
Pain
↓Improves
?
Carpal Tunnel Symptoms
↓Improves
?
Mucus Production
↑Improves
?
Mucus Production
↑Improves
?
Mucus Production
↑Improves

Research Citations (11)

The treatment of breast engorgement with Serrapeptase (Danzen): a randomised double-blind controlled trial
PMID: 2688125
A randomized, double-blind, placebo-controlled study comparing the efficacy and safety of paracetamol, serratiopeptidase, ibuprofen and betamethasone using the dental impaction pain model
PMID: 19168326
A multi-centre, double-blind study of serrapeptase versus placebo in post-antrotomy buccal swelling
PMID: 6366808
[Reduction of postoperative swelling. Objective measurement of swelling of the upper ankle joint in treatment with serrapeptase-- a prospective study]
PMID: 2647603
Comparison of the roles of serratiopeptidase and dexamethasone in the control of inflammation and trismus following impacted third molar surgery
PMID: 23649050
Evaluation of Serratia peptidase in acute or chronic inflammation of otorhinolaryngology pathology: a multicentre, double-blind, randomized trial versus placebo
PMID: 2257960
[Clinical study of the efficacy of and tolerance to seaprose S in inflammatory venous disease. Controlled study versus serratio-peptidase]
PMID: 9091835
Effect of the proteolytic enzyme serrapeptase in patients with chronic airway disease
PMID: 12911824
A preliminary trial of serratiopeptidase in patients with carpal tunnel syndrome
PMID: 11225219
Effect of expectorants on relaxation behavior of sputum viscoelasticity in vivo
PMID: 6375756

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