Pterostilbene
Pterostilbene is a dimethylated derivative of resveratrol that, for some mechanisms, is more potent. It is also much better absorbed, and is commonly referred to as a 'better resveratrol'. It looks promising, but has significantly less research than its predecessor.
Quick Answer
What it is
Pterostilbene is a dimethylated derivative of resveratrol that, for some mechanisms, is more potent. It is also much better absorbed, and is commonly referred to as a 'better resveratrol'.
Key findings
- Grade C: Blood Pressure (Coronary Artery Disease (CAD))
- Grade D: Blood glucose (Metabolic Health)
- Grade N/A: High-density lipoprotein (HDL) (Coronary Artery Disease (CAD))
Safety
No specific caution or interaction language was detected in the current summary/outcome notes.
ℹ️ Quick Facts: Pterostilbene
Quick Facts: Pterostilbene
- Best Evidence:Grade C
- Conditions Studied:5
- Research Outcomes:27
- Key Effect:Coronary Artery Disease (CAD)
Detailed Outcomes
Evidence by Condition
Best grade per condition (each condition may have multiple outcomes)
Research Citations (2)
Related Supplements
Vitamin D
5 shared conditions · 308 outcomes
Vitamin D is a fat-soluble vitamin that our skin synthesizes when exposed to the sun. It benefits us in many ways, from bone health to mood.
Saffron
5 shared conditions · 390 outcomes
Saffron is a spice with antioxidant properties derived from the flowering plant Crocus sativus. When used as a supplement, saffron seems to be effective at reducing symptoms of depression and possibly anxiety.
Fish Oil
5 shared conditions · 448 outcomes
Fish oil is a mix of mostly EPA and DHA derived from fatty fish. It reduces triglycerides, but does not seem to affect the rate of cardiovascular events. It appears to reduce the symptoms of depression and improve some painful, inflammatory conditions.
Curcumin
5 shared conditions · 502 outcomes
Curcumin is the primary bioactive substance in turmeric. It has anti-inflammatory properties and can alleviate symptoms of depression as well as improve pain and function in people with osteoarthritis.
L-Carnitine
5 shared conditions · 558 outcomes
L-carnitine can relieve leg pain in people with peripheral artery disease (PAD) and treat some aspects of metabolic syndrome. Although it’s often also used for fat loss, its effectiveness for that is questionable.
Black seed
5 shared conditions · 111 outcomes
Black seed (Nigella sativa) is one of the most evidence-backed supplements in the database. A-GRADE for allergy symptoms (3 RCTs, 257 participants, moderate improvement). B-GRADE for blood glucose (29 RCTs, 3679 participants), blood pressure (22 RCTs, 1527 participants), and C-reactive protein (11 RCTs, 727 participants). Thymoquinone is the primary active compound. Traditional Islamic medicine ('the cure for everything except death'). Extensive human research supports benefits for metabolic and inflammatory conditions. Generally safe with few drug interactions.
Whey Protein
4 shared conditions · 197 outcomes
Whey protein is one of the two high-quality proteins derived from cow’s milk (casein being the other). Its high digestibility, quick absorption, and well-researched benefits for muscle gain and cardiometabolic health make it a popular protein supplement among athletes and older adults.
Vitamin C
4 shared conditions · 262 outcomes
Vitamin C, or ascorbic acid, is an essential vitamin and a very popular supplement due to its antioxidant properties, safety profile, and low price. Many people supplement with vitamin C because it is believed to reduce symptoms of the common cold.