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Dr. Grey AI

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Pomegranate seed oil

Pomegranate seed oil is a plant oil pressed from pomegranate seeds, and like other dietary oils the body absorbs it as a source of fat. People mostly look at it for metabolic health, and the evidence is limited: in a small study of 30 people, HDL, the so-called good cholesterol, rose. In 51 people with high cholesterol, body fat and blood sugar control showed no clear difference, and that evidence is very limited.

Best evidence
Grade C
Conditions studied
3
Outcomes
14
Graded outcomes
0012

Evidence by condition

  • Strong
  • Moderate
  • Limited
  • Very limited

3 conditions

Metabolic Health: outcomes studied for Pomegranate seed oil
GradeOutcomeEffectSizeStudiesPeopleStudies list
High-density lipoprotein (HDL)

Small Improvement

Improves (the measure goes up)Small effect30 people
TriglyceridesImproves (the measure goes down)1 study30 people

Studies that measured triglycerides

Low-density lipoprotein (LDL)Improves (the measure goes down)30 people
High Cholesterol: outcomes studied for Pomegranate seed oil
GradeOutcomeEffectSizeStudiesPeopleStudies list
Body Fat

No effect

NoneNo effect51 people
Glycemic Control

No effect

NoneNo effect51 people
TNF-AlphaImproves (the measure goes down)1 study45 people

Studies that measured tnf-alpha

Total cholesterolImproves (the measure goes down)1 study51 people
TriglyceridesImproves (the measure goes down)1 study51 people

Studies that measured triglycerides

High-density lipoprotein (HDL)Improves (the measure goes up)51 people
InsulinChanges; see studies51 people
Low-density lipoprotein (LDL)Improves (the measure goes down)51 people
Muscle MassImproves (the measure goes up)51 people
WeightImproves (the measure goes down)51 people

Immune Health: outcomes studied for Pomegranate seed oil
GradeOutcomeEffectSizeStudiesPeopleStudies list
TNF-AlphaImproves (the measure goes down)1 study45 people

Studies that measured tnf-alpha

Key findings

  • High-density lipoprotein (HDL)Metabolic HealthImproves (the measure goes up)
  • Body FatHigh Cholesterol
  • Glycemic ControlHigh Cholesterol

Shop Pomegranate seed oil

Third-party tested Pomegranate seed oil products. The evidence above is limited, so read it before you buy.

  • Grade C

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Studies cited

3 studies from PubMed

  1. Effect of pomegranate seed oil on hyperlipidaemic subjects: a double-blind placebo-controlled clinical trialBr J Nutr · PMID 20334708
  2. Effect of pomegranate seed oil on serum TNF-α level in dyslipidemic patientsInt J Food Sci Nutr · PMID 22044195
  3. Incorporation and metabolism of punicic acid in healthy young humansMol Nutr Food Res · PMID 19753607