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Dr. Grey AI

Supplement

Fiber

Fiber is the part of plant foods your body can't digest, and it adds bulk to stool, softens it and slows how quickly carbohydrates are absorbed. People most often look at it for constipation-predominant irritable bowel syndrome, where the evidence is strong, especially for soluble fiber. Findings elsewhere were more modest: blood glucose improved in pregnancies with diabetes, though the studies were small, and appetite showed no clear difference.

Sources: PMID 39473074

Best evidence
Grade B
Conditions studied
6
Outcomes
24
Graded outcomes
0402

Evidence by condition

  • Strong
  • Moderate
  • Limited
  • Very limited

6 conditions

Gestational Diabetes: outcomes studied for Fiber
GradeOutcomeEffectSizeStudiesPeopleStudies list
Blood glucose

Small Improvement

Improves (the measure goes down)Small effect1 study1,061 people
HbA1cImproves (the measure goes down)1 study1,061 people
Type 1 Diabetes: outcomes studied for Fiber
GradeOutcomeEffectSizeStudiesPeopleStudies list
Glycemic Control

Small Improvement

Improves (the measure goes up)Small effect64 people
HbA1cImproves (the measure goes down)1 study87 people

Type 2 Diabetes

  • High-density lipoprotein (HDL): improves
  • Total cholesterol: improves
  • Low-density lipoprotein (LDL): improves
Type 2 Diabetes: outcomes studied for Fiber
GradeOutcomeEffectSizeStudiesPeopleStudies list
High-density lipoprotein (HDL)

Small Improvement

Improves (the measure goes up)Small effect2,580 people
Total cholesterolImproves (the measure goes down)2 studies2,580 people
Low-density lipoprotein (LDL)Improves (the measure goes down)2,580 people
TriglyceridesImproves (the measure goes down)2,580 people

Metabolic Health

  • High-density lipoprotein (HDL): improves
  • Total cholesterol: improves
  • Low-density lipoprotein (LDL): improves
Metabolic Health: outcomes studied for Fiber
GradeOutcomeEffectSizeStudiesPeopleStudies list
High-density lipoprotein (HDL)

Small Improvement

Improves (the measure goes up)Small effect291 people
Total cholesterolImproves (the measure goes down)2 studies334 people
Low-density lipoprotein (LDL)Improves (the measure goes down)334 people
TriglyceridesImproves (the measure goes down)311 people

Chronic Kidney Disease (CKD)

  • C-Reactive Protein (CRP)
  • Blood Urea Nitrogen
  • Interleukin 6: improves
Chronic Kidney Disease (CKD): outcomes studied for Fiber
GradeOutcomeEffectSizeStudiesPeopleStudies list
C-Reactive Protein (CRP)

No effect

NoneNo effect157 people
Blood Urea NitrogenSmall effect1 study498 people
Interleukin 6Improves (the measure goes down)265 people
p-cresyl sulfate (PCS)Improves (the measure goes up)398 people
Serum Indoxyl Sulfate (IS)Improves (the measure goes up)398 people
TMAOImproves (the measure goes up)135 people
TNF-AlphaImproves (the measure goes down)157 people
Uric AcidImproves (the measure goes down)118 people

Weight Loss & Maintenance

  • Appetite
  • Liver Fat: improves
  • Bifidobacterium Abundance: improves
Weight Loss & Maintenance: outcomes studied for Fiber
GradeOutcomeEffectSizeStudiesPeopleStudies list
Appetite

No effect

NoneNo effect43 people
Liver FatImproves (the measure goes down)1 study43 people
Bifidobacterium AbundanceImproves (the measure goes up)43 people
Visceral FatImproves (the measure goes down)43 people

What the published studies found

1 automated reading

Automated reading of the published studies (Decosa evidence engine), for outcomes Dr. Grey has not graded yet. It is not a Dr. Grey grade and does not change one. How it is read

Key findings

  • Blood glucoseGestational DiabetesImproves (the measure goes down)
  • Glycemic ControlType 1 DiabetesImproves (the measure goes up)
  • High-density lipoprotein (HDL)Type 2 DiabetesImproves (the measure goes up)

Shop the evidence-backed picks

Third-party tested Fiber products, in the forms the graded studies used where we can match them.

  • Grade B

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Studies cited

5 studies from PubMed

  1. The effect of high-fibre diets on glycaemic control in women with diabetes in pregnancy: A systematic review and meta-analysis.Diabet Med · PMID 39473074
  2. Does glucomannan supplementation exert profitable effects on serum lipid profile in adults? A systematic review and meta-analysis.Prostaglandins Other Lipid Mediat · PMID 39528010
  3. Effect of soluble fiber supplementation on lipid parameters in subjects with type 2 diabetes: A systematic review and meta-analysis of randomized controlled trials.Prostaglandins Other Lipid Mediat · PMID 39689417
  4. Effects of Dietary Fiber Supplementation on Modulating Uremic Toxins and Inflammation in Chronic Kidney Disease Patients: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.Toxins · PMID 39998074
  5. Effects of different dietary patterns on glucose management in type 1 diabetes: a systematic review and meta-analysis of randomized controlled trials.EClinicalMedicine · PMID 40641818