Exogenous Ketones

Exogenous ketones are supplements that mimic ketosis by increasing ketone bodies in the blood. Supplementation with exogenous ketones might improve glycemic control, cognition, and heart function.

Quick Answer

What it is

Exogenous ketones are supplements that mimic ketosis by increasing ketone bodies in the blood. Supplementation with exogenous ketones might improve glycemic control, cognition, and heart function.

Key findings

  • Grade B: Blood glucose (Metabolic Health)
  • Grade D: Aerobic Exercise Metrics (Aerobic Exercise Performance)
  • Grade N/A: Ketone Bodies (Metabolic Health)

Safety

No specific caution or interaction language was detected in the current summary/outcome notes.

ℹ️ Quick Facts: Exogenous Ketones

Quick Facts: Exogenous Ketones

  • Best Evidence:Grade B
  • Conditions Studied:3
  • Research Outcomes:14
  • Grade B Findings:1
  • Key Effect:Metabolic Health
Outcomes by grade:
A0
B1
C1
D1
3 conditions · 14 outcomes

Detailed Outcomes

|
B
Blood glucose
Small Improvement
33 studies
smallImproves
?
Ketone Bodies
Improves
C
Blood glucose
Small Improvement
1 study
smallImproves
?
Blood Lactate (Exercise)
1 study
Worsens
?
Blood Pressure
1 study
Improves
?
Cardiac Output
1 study
Improves
?
End-Diastolic Volume
1 study
Improves
?
Free Fatty Acids
1 study
Improves
?
Heart Rate
1 study
Improves
?
Insulin
1 study
Worsens
?
Left Ventricular Ejection Fraction
Improves
?
Stroke Volume
1 study
Improves
D
Aerobic Exercise Metrics
No effect
none
?
Sleep Quality
Improves

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