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Ecdysteroids

Ecdysteroids are steroid-like compounds made by plants, chemically related to the hormones insects use to molt, though their role in the human body is still unclear. Some people look at them for body composition, and research found no clear difference in muscle mass or cortisol among 45 participants. The evidence is very limited, so this is a small early look rather than a firm answer either way.

Best evidence
Grade D
Conditions studied
4
Outcomes
25
Graded outcomes
0005

Evidence by condition

  • Strong
  • Moderate
  • Limited
  • Very limited

4 conditions

Body Composition: outcomes studied for Ecdysteroids
GradeOutcomeEffectSizeStudiesPeopleStudies list
Cortisol

No effect

NoneNo effect45 people
Muscle Mass

No effect

NoneNo effect45 people
TestosteroneImproves (the measure goes up)1 study45 people
Power OutputImproves (the measure goes up)45 people

Muscle Size Strength

Muscle Size Strength: outcomes studied for Ecdysteroids
GradeOutcomeEffectSizeStudiesPeopleStudies list
Cortisol

No effect

NoneNo effect45 people
TestosteroneImproves (the measure goes up)1 study45 people
Liver EnzymesChanges; see studies45 people
Muscle MassImproves (the measure goes up)45 people
Power OutputImproves (the measure goes up)45 people
Total cholesterolImproves (the measure goes down)45 people
TriglyceridesImproves (the measure goes down)45 people

General Athletic Performance

  • Cortisol
  • Testosterone: improves
  • Liver Enzymes: changes; see studies
General Athletic Performance: outcomes studied for Ecdysteroids
GradeOutcomeEffectSizeStudiesPeopleStudies list
Cortisol

No effect

NoneNo effect45 people
TestosteroneImproves (the measure goes up)1 study45 people
Liver EnzymesChanges; see studies45 people
Muscle MassImproves (the measure goes up)45 people
Power OutputImproves (the measure goes up)45 people
Total cholesterolImproves (the measure goes down)45 people
TriglyceridesImproves (the measure goes down)45 people

Muscle Size & Strength

  • Cortisol
  • Testosterone: improves
  • Liver Enzymes: changes; see studies
Muscle Size & Strength: outcomes studied for Ecdysteroids
GradeOutcomeEffectSizeStudiesPeopleStudies list
Cortisol

No effect

NoneNo effect45 people
TestosteroneImproves (the measure goes up)1 study45 people
Liver EnzymesChanges; see studies45 people
Muscle MassImproves (the measure goes up)45 people
Power OutputImproves (the measure goes up)45 people
Total cholesterolChanges; see studies45 people
TriglyceridesChanges; see studies45 people

Key findings

  • CortisolBody Composition
  • Muscle MassBody Composition

Shop Ecdysteroids

Third-party tested Ecdysteroids products. The evidence above is limited, so read it before you buy.

  • Grade D

Links to Fullscript, iHerb or Thorne carry our referral, so we may earn a commission at no extra cost to you. Grades come from the research and never change based on what we earn. Fullscript asks for a free account before it shows its catalog and prices. Full disclosure

Studies cited

1 study from PubMed

  1. Effects of methoxyisoflavone, ecdysterone, and sulfo-polysaccharide supplementation on training adaptations in resistance-trained malesJ Int Soc Sports Nutr · PMID 18500969