Supplement
Casein is the main protein in milk, digested slowly so it releases amino acids into the blood over several hours, and it also supplies building blocks for muscle and other tissues. People most often look at it for blood pressure in those with high readings, and the evidence is moderate: blood pressure improved, meaning it went down. Those results came from small studies of 183 people, and blood glucose showed no clear difference, with very limited evidence.
- Updated
- How we grade
- Best evidence
- Grade B
- Conditions studied
- 4
- Outcomes
- 28
- Graded outcomes
- 0104
Evidence by condition
- Strong
- Moderate
- Limited
- Very limited
| Grade | Outcome | Effect | Size | Studies | People | Studies list |
|---|---|---|---|---|---|---|
| Blood Pressure Small Improvement | Improves (the measure goes down) | Small effect | 183 people | |||
| Blood glucose No effect | NoneNo effect | 80 people | ||||
| Triglycerides | Improves (the measure goes down) | 1 study | 121 people | |||
| High-density lipoprotein (HDL) | Improves (the measure goes up) | 121 people | ||||
| Insulin | Changes; see studies | 30 people | ||||
| Low-density lipoprotein (LDL) | Improves (the measure goes down) | 121 people | ||||
| Total cholesterol | Improves (the measure goes down) | 121 people | ||||
| Grade | Outcome | Effect | Size | Studies | People | Studies list |
|---|---|---|---|---|---|---|
| Blood glucose No effect | NoneNo effect | 80 people | ||||
| Triglycerides | Improves (the measure goes down) | 1 study | 121 people | |||
| Blood Pressure | Improves (the measure goes down) | 183 people | ||||
| High-density lipoprotein (HDL) | Improves (the measure goes up) | 121 people | ||||
| Insulin | Changes; see studies | 30 people | ||||
| Low-density lipoprotein (LDL) | Improves (the measure goes down) | 121 people | ||||
| Total cholesterol | Improves (the measure goes down) | 121 people | ||||
Type 2 Diabetes
- Blood glucose
- Triglycerides: improves
- Blood Pressure: improves
| Grade | Outcome | Effect | Size | Studies | People | Studies list |
|---|---|---|---|---|---|---|
| Blood glucose No effect | NoneNo effect | 80 people | ||||
| Triglycerides | Improves (the measure goes down) | 1 study | 121 people | |||
| Blood Pressure | Improves (the measure goes down) | 183 people | ||||
| High-density lipoprotein (HDL) | Improves (the measure goes up) | 121 people | ||||
| Insulin | Changes; see studies | 30 people | ||||
| Low-density lipoprotein (LDL) | Improves (the measure goes down) | 121 people | ||||
| Total cholesterol | Improves (the measure goes down) | 121 people | ||||
Metabolic Syndrome
- Blood glucose
- Triglycerides: improves
- Blood Pressure: improves
| Grade | Outcome | Effect | Size | Studies | People | Studies list |
|---|---|---|---|---|---|---|
| Blood glucose No effect | NoneNo effect | 80 people | ||||
| Triglycerides | Improves (the measure goes down) | 1 study | 121 people | |||
| Blood Pressure | Improves (the measure goes down) | 183 people | ||||
| High-density lipoprotein (HDL) | Improves (the measure goes up) | 121 people | ||||
| Insulin | Changes; see studies | 30 people | ||||
| Low-density lipoprotein (LDL) | Improves (the measure goes down) | 121 people | ||||
| Total cholesterol | Improves (the measure goes down) | 121 people | ||||
Key findings
- Blood PressureImproves (the measure goes down)
- Blood glucose
Shop the evidence-backed picks
Third-party tested Casein products, in the forms the graded studies used where we can match them.
- Grade B
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