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Condition

Tennis Performance

Tennis is an intermittent sport that blends power, agility, endurance, and focus, with matches lasting anywhere from one to five-plus hours. Among supplements, the evidence is strongest for caffeine, electrolytes, and whey protein, which are linked to alertness and endurance, hydration in long or hot matches, and muscle recovery. Creatine has moderate evidence, while citrulline has very limited research, with one small study of 21 people finding no clear difference in anaerobic capacity.

Supplements studied
3
Graded outcomes
1
Trials
3
People studied
66

Evidence by supplement

  • Strong
  • Moderate
  • Limited
  • Very limited

3 supplements

Citrulline: outcomes studied for Tennis Performance
GradeOutcomeEffectSizeStudiesPeopleStudies list
Anaerobic Capacity

No effect

NoneNo effect21 people
Power OutputImproves (the measure goes up)3 studies21 people
StrengthImproves (the measure goes up)21 people
Sodium Bicarbonate: outcomes studied for Tennis Performance
GradeOutcomeEffectSizeStudiesPeopleStudies list
Neuromuscular FunctionImproves (the measure goes up)2 studies9 people

Studies that measured neuromuscular function

Creatine: outcomes studied for Tennis Performance
GradeOutcomeEffectSizeStudiesPeopleStudies list
Sprint Performance MetricsImproves (the measure goes up)1 study36 people

Studies that measured sprint performance metrics

Key findings

  • Anaerobic CapacityCitrulline

The Tennis Performance Enhancement protocol

2 primary supplements · 3 supporting supplements

See the full protocol

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Studies cited

100 studies from PubMed

  1. Does creatine supplementation improve glycemic control and insulin resistance in healthy and diabetic patients? A systematic review and meta-analysis.Clin Nutr ESPEN, 2022 · PMID 35063192
  2. Role of creatine supplementation on exercise-induced cardiovascular function and oxidative stressOxid Med Cell Longev, 2009 · PMID 20716911
  3. Three weeks of creatine monohydrate supplementation affects dihydrotestosterone to testosterone ratio in college-aged rugby playersClin J Sport Med, 2009 · PMID 19741313
  4. Does creatine supplementation improve the plasma lipid profile in healthy male subjects undergoing aerobic trainingJ Int Soc Sports Nutr, 2008 · PMID 18831767
  5. Effects of creatine supplementation on glucose tolerance and insulin sensitivity in sedentary healthy males undergoing aerobic trainingAmino Acids, 2008 · PMID 17396216
  6. Creatine supplementation increases glycogen storage but not GLUT-4 expression in human skeletal muscleClin Sci (Lond), 2004 · PMID 14507259
  7. Creatine supplementation affects glucose homeostasis but not insulin secretion in humansAnn Nutr Metab, 2003 · PMID 12624482
  8. Creatine supplementation and health variables: a retrospective studyMed Sci Sports Exerc, 2001 · PMID 11224803
  9. Effect of oral creatine supplementation on human muscle GLUT4 protein content after immobilizationDiabetes, 2001 · PMID 11147785
  10. Role of submaximal exercise in promoting creatine and glycogen accumulation in human skeletal muscle1999 · PMID 10444618
  11. l-Citrulline supplementation improves O2 uptake kinetics and high-intensity exercise performance in humansJ Appl Physiol, 1985 · PMID 26023227
  12. Effects of supplemental citrulline malate ingestion during repeated bouts of lower-body exercise in advanced weightliftersJ Strength Cond Res · PMID 25226311
  13. The Effect of Citrulline/Malate on Blood Lactate Levels in Intensive ExerciseBiochem Genet · PMID 28664349
  14. Citrulline Malate Fails to Improve German Volume Training Performance in Healthy Young Men and WomenJ Diet Suppl · PMID 30458655
  15. L-citrulline reduces time to exhaustion and insulin response to a graded exercise testMed Sci Sports Exerc · PMID 16679980
  16. Effects of Supplemental Citrulline-Malate Ingestion on Blood Lactate, Cardiovascular Dynamics, and Resistance Exercise Performance in Trained MalesJ Diet Suppl · PMID 25674699
  17. Effects of Citrulline Malate and Beetroot Juice Supplementation on Blood Flow, Energy Metabolism, and Performance During Maximum Effort Leg Extension ExerciseJ Strength Cond Res · PMID 31343548
  18. Eight weeks of resistance training in conjunction with glutathione and L-Citrulline supplementation increases lean mass and has no adverse effects on blood clinical safety markers in resistance-trained malesJ Int Soc Sports Nutr · PMID 29945625
  19. Citrulline/malate promotes aerobic energy production in human exercising muscleBr J Sports Med · PMID 12145119
  20. Citrulline malate enhances athletic anaerobic performance and relieves muscle sorenessJ Strength Cond Res · PMID 20386132
  21. Acute Effect of Citrulline Malate Supplementation on Upper-Body Resistance Exercise Performance in Recreationally Resistance-Trained MenJ Strength Cond Res · PMID 29210953
  22. Acute citrulline malate supplementation improves upper- and lower-body submaximal weightlifting exercise performance in resistance-trained femalesEur J Nutr · PMID 26658899
  23. Acute Effects of Citrulline Supplementation on High-Intensity Strength and Power Performance: A Systematic Review and Meta-AnalysisSports Med · PMID 30895562
  24. Acute citrulline-malate supplementation improves maximal strength and anaerobic power in female, masters athletes tennis playersEur J Sport Sci · PMID 27017895
  25. Impact of L-citrulline supplementation and whole-body vibration training on arterial stiffness and leg muscle function in obese postmenopausal women with high blood pressureExp Gerontol · PMID 25636814
  26. Impact of l-citrulline supplementation on oxygen uptake kinetics during walkingAppl Physiol Nutr Metab · PMID 29394491
  27. Effects of L-citrulline oral supplementation on polymorphonuclear neutrophils oxidative burst and nitric oxide production after exerciseFree Radic Res · PMID 19585317
  28. Oral L-citrulline supplementation enhances cycling time trial performance in healthy trained men: Double-blind randomized placebo-controlled 2-way crossover studyJ Int Soc Sports Nutr · PMID 26900386
  29. Acute citrulline-malate supplementation is ineffective during aerobic cycling and subsequent anaerobic performance in recreationally active malesEur J Sport Sci · PMID 31994989
  30. One Week of L-Citrulline Supplementation Improves Performance in Trained CyclistsJ Strength Cond Res · PMID 31860534
  31. Oral L-citrulline supplementation attenuates blood pressure response to cold pressor test in young menAm J Hypertens · PMID 19851298
  32. The effects of short term L-citrulline supplementation on wave reflection responses to cold exposure with concurrent isometric exerciseAm J Hypertens · PMID 23467207
  33. l-Citrulline supplementation attenuates blood pressure, wave reflection and arterial stiffness responses to metaboreflex and cold stress in overweight menBr J Nutr · PMID 27160957
  34. Does l-citrulline supplementation improve exercise blood flow in older adults?Exp Physiol · PMID 28940638
  35. Effect of oral L-citrulline on brachial and aortic blood pressure defined by resting status: evidence from randomized controlled trialsNutr Metab · PMID 31889969
  36. Acute effects of Nitrosigine® and citrulline malate on vasodilation in young adultsJ Int Soc Sports Nutr · PMID 32093766
  37. Acute Citrulline-Malate Supplementation and High-Intensity Cycling PerformanceJ Strength Cond Res · PMID 26808848
  38. Oxidative stress and nitrate/nitrite (NOx) status following citrulline supplementation in type 2 diabetes: a randomised, double-blind, placebo-controlled trialJ Hum Nutr Diet · PMID 32683790
  39. Improvement of ventricular function in systolic heart failure patients with oral L-citrulline supplementationCardiol J · PMID 23224924
  40. Effect of L-arginine or L-citrulline oral supplementation on blood pressure and right ventricular function in heart failure patients with preserved ejection fractionCardiol J · PMID 21154265
  41. Effect of citrulline on post-exercise rating of perceived exertion, muscle soreness, and blood lactate levels: A systematic review and meta-analysis.J Sport Health Sci · PMID 33308806
  42. Citrulline Malate Does Not Improve Muscle Recovery after Resistance Exercise in Untrained Young Adult MenNutrients · PMID 29057836
  43. L-citrulline improves splanchnic perfusion and reduces gut injury during exerciseMed Sci Sports Exerc · PMID 24621960
  44. Short-term effects of L-citrulline supplementation on arterial stiffness in middle-aged menInt J Cardiol · PMID 21067832
  45. Inter-Individual Responses to Citrulline Malate Oral Supplementation on Post-Exercise Hypotension in Hypertensives: A 24-Hour AnalysisArq Bras Cardiol · PMID 31291417
  46. Acute Effects of Citrulline Malate Supplementation on Nocturnal Blood Pressure Dipping After Exercise in Hypertensive Patients: A Randomized, Placebo-Controlled Trial.J Diet Suppl · PMID 39385595
  47. L-Citrulline increases nitric oxide and improves control in obese asthmaticsJCI Insight · PMID 31714895
  48. Chronic l-citrulline supplementation improves cardiac sympathovagal balance in obese postmenopausal women: A preliminary reportAuton Neurosci · PMID 27356482
  49. Inflammatory markers response to citrulline supplementation in patients with non-alcoholic fatty liver disease: a randomized, double blind, placebo-controlled, clinical trialBMC Res Notes · PMID 30767788
  50. Oral l-citrulline malate in patients with idiopathic pulmonary arterial hypertension and Eisenmenger Syndrome: a clinical trialJ Cardiol · PMID 24525046
  51. L-citrulline-malate influence over branched chain amino acid utilization during exerciseEur J Appl Physiol · PMID 20499249
  52. Dose-ranging effects of citrulline administration on plasma amino acids and hormonal patterns in healthy subjects: the Citrudose pharmacokinetic studyBr J Nutr · PMID 17953788
  53. Oral citrulline does not affect whole body protein metabolism in healthy human volunteers: results of a prospective, randomized, double-blind, cross-over studyClin Nutr · PMID 21733603
  54. Oral L-citrulline supplementation improves erection hardness in men with mild erectile dysfunctionUrology · PMID 21195829
  55. Nitric oxide precursors and congenital heart surgery: a randomized controlled trial of oral citrullineJ Thorac Cardiovasc Surg · PMID 16798303
  56. Effect of creatine monohydrate in improving cellular energetics and muscle strength in ambulatory Duchenne muscular dystrophy patients: a randomized, placebo-controlled 31P MRS studyMagn Reson Imaging · PMID 20395096
  57. Creatine for treating muscle disorders.Cochrane Database Syst Rev · PMID 23740606
  58. Creatine monohydrate enhances strength and body composition in Duchenne muscular dystrophyNeurology · PMID 15159476
  59. Comparison of creatine ingestion and resistance training on energy expenditure and limb blood flowMetabolism · PMID 11735088
  60. Creatine, arginine alpha-ketoglutarate, amino acids, and medium-chain triglycerides and endurance and performanceInt J Sport Nutr Exerc Metab · PMID 19033611
  61. The effects of creatine ethyl ester supplementation combined with heavy resistance training on body composition, muscle performance, and serum and muscle creatine levelsJ Int Soc Sports Nutr · PMID 19228401
  62. Effect of in-season creatine supplementation on body composition and performance in rugby union football playersAppl Physiol Nutr Metab · PMID 18059577
  63. Creatine fails to augment the benefits from resistance training in patients with HIV infection: a randomized, double-blind, placebo-controlled studyPLoS One · PMID 19242554
  64. Effect of creatine and weight training on muscle creatine and performance in vegetariansMed Sci Sports Exerc · PMID 14600563
  65. Effects of creatine supplementation in taekwondo practitionersNutr Hosp · PMID 23822690
  66. Creatine supplementation improves muscular performance in older womenEur J Appl Physiol · PMID 17943308
  67. The effects of creatine monohydrate supplementation with and without D-pinitol on resistance training adaptationsJ Strength Cond Res · PMID 19858753
  68. Effects of creatine on body composition and strength gains after 4 weeks of resistance training in previously nonresistance-trained humansInt J Sport Nutr Exerc Metab · PMID 14967873
  69. Creatine monohydrate supplementation on body weight and percent body fatJ Strength Cond Res · PMID 14636103
  70. Reliability and detecting change following short-term creatine supplementation: comparison of two-component body composition methodsJ Strength Cond Res · PMID 17530953
  71. Low-dose creatine supplementation enhances fatigue resistance in the absence of weight gainNutrition · PMID 20591625
  72. Efficacy of Creatine Supplementation Combined with Resistance Training on Muscle Strength and Muscle Mass in Older Females: A Systematic Review and Meta-Analysis.Nutrients · PMID 34836013
  73. The Paradoxical Effect of Creatine Monohydrate on Muscle Damage Markers: A Systematic Review and Meta-AnalysisSports Med · PMID 35218552
  74. Creatine supplementation and physical training in patients with COPD: a double blind, placebo-controlled studyInt J Chron Obstruct Pulmon Dis · PMID 18044100
  75. Creatine monohydrate increases strength in patients with neuromuscular diseaseNeurology · PMID 10078740
  76. Effect of creatine ingestion after exercise on muscle thickness in males and femalesMed Sci Sports Exerc · PMID 15595301
  77. Does nutritional supplementation influence adaptability of muscle to resistance training in men aged 48 to 72 yearsJ Geriatr Phys Ther · PMID 16236227
  78. Effects of four weeks of high-intensity interval training and creatine supplementation on critical power and anaerobic working capacity in college-aged menJ Strength Cond Res · PMID 19675499
  79. Effect of creatine and beta-alanine supplementation on performance and endocrine responses in strength/power athletesInt J Sport Nutr Exerc Metab · PMID 17136944
  80. Effect of short-term creatine supplementation on neuromuscular functionMed Sci Sports Exerc · PMID 19727018
  81. The effects of polyethylene glycosylated creatine supplementation on muscular strength and powerJ Strength Cond Res · PMID 21068676
  82. Effect of thirty days of creatine supplementation with phosphate salts on anaerobic working capacity and body weight in menJ Strength Cond Res · PMID 18438234
  83. The effects of supplementation with creatine and protein on muscle strength following a traditional resistance training program in middle-aged and older menJ Nutr Health Aging · PMID 20126965
  84. The effects of pre versus post workout supplementation of creatine monohydrate on body composition and strengthJ Int Soc Sports Nutr · PMID 23919405
  85. Effect of different frequencies of creatine supplementation on muscle size and strength in young adultsJ Strength Cond Res · PMID 21512399
  86. Effects of creatine monohydrate and polyethylene glycosylated creatine supplementation on muscular strength, endurance, and power outputJ Strength Cond Res · PMID 19387397
  87. The effects of creatine supplementation on muscular performance and body composition responses to short-term resistance training overreachingEur J Appl Physiol · PMID 14685870
  88. Creatine as a metabolic controller of skeletal muscles structure and function in strength exercises in humansRoss Fiziol Zh Im I M Sechenova · PMID 16613062
  89. Effects of creatine monohydrate supplementation on body composition and strength indices in experienced resistance trained womenJ Strength Cond Res · PMID 17194243
  90. Effects of oral creatine and resistance training on serum myostatin and GASP-1Mol Cell Endocrinol · PMID 20026378
  91. Effects of two and five days of creatine loading on muscular strength and anaerobic power in trained athletesJ Strength Cond Res · PMID 19387386
  92. Effects of high dose oral creatine supplementation on anaerobic capacity of elite wrestlersJ Sports Med Phys Fitness · PMID 14767410
  93. The effects of four weeks of creatine supplementation and high-intensity interval training on cardiorespiratory fitness: a randomized controlled trialJ Int Soc Sports Nutr · PMID 19909536
  94. Effect of caffeine ingestion after creatine supplementation on intermittent high-intensity sprint performanceEur J Appl Physiol · PMID 21207054
  95. Effects of creatine supplementation and three days of resistance training on muscle strength, power output, and neuromuscular functionJ Strength Cond Res · PMID 17685691
  96. Mg2+-creatine chelate and a low-dose creatine supplementation regimen improve exercise performanceJ Strength Cond Res · PMID 15142029
  97. Physiological responses to short-term exercise in the heat after creatine loadingMed Sci Sports Exerc · PMID 11445756
  98. Skeletal muscle total creatine content and creatine transporter gene expression in vegetarians prior to and following creatine supplementationInt J Sport Nutr Exerc Metab · PMID 15673098
  99. Muscle glycogen supercompensation is enhanced by prior creatine supplementationMed Sci Sports Exerc · PMID 11445755
  100. Effect of creatine on aerobic and anaerobic metabolism in skeletal muscle in swimmersBr J Sports Med · PMID 8889115