Hyperuricemia
Hyperuricemia is a condition of elevated uric acid in the blood as a result of increased uric acid production, decreased excretion of uric acid, or both.
Quick Answer
What it is
Hyperuricemia is a condition of elevated uric acid in the blood as a result of increased uric acid production, decreased excretion of uric acid, or both.
Key findings
- Grade C: Uric Acid (IP6)
- Grade C: Blood glucose (Curcumin)
- Grade D: C-Reactive Protein (CRP) (Riboflavin (Vitamin B2))
Safety
No specific caution or interaction language was detected in the current summary/outcome notes.
ℹ️ Quick Facts
Quick Facts: Hyperuricemia
- Supplements Studied:5
- Research Trials:6
- Total Participants:442
- Top Supplement:IP6 (C)
Evidence-Based Protocol
Supplement stack ranked by research quality
Primary Stack (Tier 1)
Increases uric acid excretion; lowers serum uric acid levels in studies
Contains anthocyanins that may inhibit xanthine oxidase and reduce uric acid
Supporting Stack (Tier 2)
Inhibits xanthine oxidase; may reduce uric acid production
May inhibit xanthine oxidase; some studies show uric acid reduction
Traditional remedy; may help lower uric acid and reduce inflammation
Anti-inflammatory; may help with gout symptoms if hyperuricemia progresses
Anti-inflammatory; may help reduce inflammation associated with high uric acid
How It Works
Hyperuricemia is elevated uric acid levels in the blood (typically >6.8 mg/dL in men, >6 mg/dL in women). Uric acid is produced when the body breaks down purines (found in certain foods and drinks). High levels can lead to gout (painful crystal deposits in joints) and kidney stones.
WHY URIC ACID RISES:
RISK FACTORS:
CONSEQUENCES:
DIETARY MODIFICATIONS:
WHEN MEDICATION IS NEEDED:
* Vitamin C can lower uric acid by about 0.5 mg/dL at higher doses.
* Tart cherry has shown uric acid-lowering effects and gout prevention.
* Quercetin may inhibit the enzyme that produces uric acid.
Expected timeline: Dietary and supplement interventions may take 4-8 weeks to show measurable effects on uric acid levels.
Supplements for Hyperuricemia
Sorted by strength of evidence
Detailed Outcomes
Research Citations (100)
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