Condition
Breast Pain
Breast pain, or mastalgia, is very common, either following the menstrual cycle or not, and it is rarely a sign of breast cancer. Evening primrose oil and vitamin E are the supplements people turn to most, but little research on them has been reviewed here so far. Vitex, vitamin B6 and magnesium get attention too, though their evidence is limited to moderate.
- Supplements studied
- 5
- Graded outcomes
- 0
- Trials
- 5
- People studied
- 1,610
Evidence by supplement
- Strong
- Moderate
- Limited
- Very limited
| Grade | Outcome | Effect | Size | Studies | People | Studies list |
|---|---|---|---|---|---|---|
| Breast Tenderness | Improves (the measure goes down) | 1 study | 80 people | |||
Studies that measured breast tenderness | ||||||
| Grade | Outcome | Effect | Size | Studies | People | Studies list |
|---|---|---|---|---|---|---|
| Breast Tenderness | Improves (the measure goes down) | 1 study | 240 people | |||
Studies that measured breast tenderness | ||||||
Yarrow
- Nipple Cracks: improves
| Grade | Outcome | Effect | Size | Studies | People | Studies list |
|---|---|---|---|---|---|---|
| Nipple Cracks | Improves (the measure goes up) | 1 study | 150 people | |||
Studies that measured nipple cracks | ||||||
Evening Primrose Oil
- Breast Tenderness: improves
| Grade | Outcome | Effect | Size | Studies | People | Studies list |
|---|---|---|---|---|---|---|
| Breast Tenderness | Improves (the measure goes down) | 1 study | 525 people | |||
Studies that measured breast tenderness | ||||||
Chaste tree
- Breast Tenderness: improves
| Grade | Outcome | Effect | Size | Studies | People | Studies list |
|---|---|---|---|---|---|---|
| Breast Tenderness | Improves (the measure goes down) | 1 study | 159 people | |||
Studies that measured breast tenderness | ||||||
The Breast Pain (Mastalgia) Support protocol
2 primary supplements · 6 supporting supplements
- Evening Primrose Oil1,000–3,000 mg daily
- Vitamin E400–800 IU daily
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Studies cited
1 study from PubMed