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Condition

Boxing Performance

Boxing performance rests on explosive punching power, quick hands and reactions, and the stamina to keep working through twelve three-minute rounds. The evidence is strongest for creatine and caffeine, both studied for power output and repeated hard efforts, with caffeine also looked at for reaction time. Blood acidity went down in a few studies of sodium bicarbonate, but those were tiny, so that evidence is limited.

Sources: PMID 29546641

Supplements studied
1
Graded outcomes
1
Trials
1
People studied
10

Evidence by supplement

  • Strong
  • Moderate
  • Limited
  • Very limited

1 supplement

Sodium Bicarbonate: outcomes studied for Boxing Performance
GradeOutcomeEffectSizeStudiesPeopleStudies list
Blood Acidity

Moderate Decrease

Improves (the measure goes down)Moderate effect4 studies10 people
Serum BicarbonateImproves (the measure goes up)26 studies10 people
Rating of Perceived ExertionImproves (the measure goes up)4 studies10 people
Neuromuscular FunctionImproves (the measure goes up)2 studies10 people

Studies that measured neuromuscular function

Heart RateImproves (the measure goes down)10 people

Key findings

  • Blood AciditySodium BicarbonateImproves (the measure goes down)

The Boxing Performance Support protocol

2 primary supplements · 7 supporting supplements

  • Creatine Monohydrate3–5 g daily (consider weight class implications)
  • Caffeine3–6 mg/kg 30–60 minutes before training/competition

See the full protocol

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Studies cited

69 studies from PubMed

  1. Effect of β-alanine plus sodium bicarbonate on high-intensity cycling capacityMed Sci Sports Exerc · PMID 21407127
  2. Induced alkalosis and caffeine supplementation: effects on 2,000-m rowing performanceInt J Sport Nutr Exerc Metab · PMID 21799214
  3. Effects of various sodium bicarbonate loading protocols on the time-dependent extracellular buffering profileJ Strength Cond Res · PMID 20040895
  4. Acid-base balance during repeated bouts of exercise: influence of HCO3Int J Sports Med · PMID 6094373
  5. Effects of sodium bicarbonate ingestion on prolonged intermittent exerciseMed Sci Sports Exerc · PMID 12900682
  6. The acute reversal of a diet-induced metabolic acidosis does not restore endurance capacity during high-intensity exercise in manEur J Appl Physiol Occup Physiol · PMID 8861677
  7. Metabolic and blood catecholamine responses to exercise during alkalosisMed Sci Sports Exerc · PMID 3386500
  8. Effect of induced alkalosis on exhaustive leg press performanceMed Sci Sports Exerc · PMID 9565933
  9. Induced metabolic alkalosis affects muscle metabolism and repeated-sprint abilityMed Sci Sports Exerc · PMID 15126714
  10. The effects of buffer ingestion on metabolic factors related to distance running performanceEur J Appl Physiol Occup Physiol · PMID 8851907
  11. Influence of sodium bicarbonate ingestion on plasma ammonia accumulation during incremental exercise in manEur J Appl Physiol Occup Physiol · PMID 8381081
  12. Effects of chronic bicarbonate ingestion on the performance of high-intensity workEur J Appl Physiol Occup Physiol · PMID 10483803
  13. Acute versus chronic sodium bicarbonate ingestion and anaerobic work and power outputJ Sports Med Phys Fitness · PMID 11687764
  14. Effects of chronic NaHCO3 ingestion during interval training on changes to muscle buffer capacity, metabolism, and short-term endurance performanceJ Appl Physiol · PMID 16627675
  15. Increased blood pH but not performance with sodium bicarbonate supplementation in elite rugby union playersInt J Sport Nutr Exerc Metab · PMID 20739719
  16. Effect of sodium bicarbonate ingestion on exhaustive resistance exercise performanceMed Sci Sports Exerc · PMID 8396707
  17. Acidosis stimulates beta-endorphin release during exerciseJ Appl Physiol · PMID 7836218
  18. Sodium bicarbonate improves swimming performanceInt J Sports Med · PMID 18004687
  19. Sodium bicarbonate ingestion and repeated swim sprint performanceJ Strength Cond Res · PMID 20881504
  20. Sodium bicarbonate ingestion improves performance in interval swimmingEur J Appl Physiol Occup Physiol · PMID 2849539
  21. Effects of sodium bicarbonate, caffeine, and their combination on repeated 200-m freestyle performanceInt J Sport Nutr Exerc Metab · PMID 18458356
  22. Treatment of metabolic acidosis in patients with stage 3 chronic kidney disease with fruits and vegetables or oral bicarbonate reduces urine angiotensinogen and preserves glomerular filtration rateKidney Int · PMID 24694986
  23. Efficacy and safety of oral sodium bicarbonate in kidney-transplant recipients and non-transplant patients with chronic kidney disease: a systematic review and meta-analysis.Front Pharmacol · PMID 39253380
  24. The effect of sodium bicarbonate ingestion on 1500-m racing timeJ Sports Sci · PMID 8558626
  25. Effects of induced alkalosis on simulated match performance in elite female water polo playersInt J Sport Nutr Exerc Metab · PMID 20601737
  26. The effect of sodium bicarbonate ingestion on high-intensity intermittent running and subsequent performanceJ Strength Cond Res · PMID 20555273
  27. The effects of sodium bicarbonate and sodium citrate on 600 m running time of trained femalesJ Sports Med Phys Fitness · PMID 8775646
  28. Metabolic alkalosis, recovery and sprint performanceInt J Sports Med · PMID 20703975
  29. The effects of combined glucose-electrolyte and sodium bicarbonate ingestion on prolonged intermittent exercise performanceJ Sports Sci · PMID 22616569
  30. Repeated bouts of sprint running after induced alkalosisJ Sports Sci · PMID 1664869
  31. Influence of pre-exercise acidosis and alkalosis on the kinetics of acid-base recovery following intense exerciseInt J Sport Nutr Exerc Metab · PMID 15902990
  32. No effect of bicarbonate treatment on insulin sensitivity and glucose control in non-diabetic older adultsEndocrine · PMID 21046483
  33. Effects of changes in acid base and calcium concentration on fasting serum insulin, proinsulin, and glucose concentrationsJ Clin Pathol · PMID 7829693
  34. Time course of blood bicarbonate and pH three hours after sodium bicarbonate ingestionInt J Sports Physiol Perform · PMID 19208932
  35. Effects of sodium bicarbonate on nitrogen metabolism and ketone bodies during very low energy protein diets in obese subjectsMetabolism · PMID 2556622
  36. Systemic pH modifies ketone body production rates and lipolysis in humansAm J Physiol · PMID 1975988
  37. Sodium acetate induces a metabolic alkalosis but not the increase in fatty acid oxidation observed following bicarbonate ingestion in humansJ Nutr · PMID 17585026
  38. Does bicarbonated mineral water rich in sodium change insulin sensitivity of postmenopausal womenNutr Hosp · PMID 17970536
  39. Effects of sodium bicarbonate ingestion on performance and perceptual responses in a laboratory-simulated BMX cycling qualification seriesJ Strength Cond Res · PMID 18714219
  40. Effect of sodium bicarbonate on muscle metabolism during intense endurance cyclingMed Sci Sports Exerc · PMID 11932569
  41. Bicarbonate ingestion has no ergogenic effect on consecutive all out sprint tests in BMX elite cyclistsEur J Appl Physiol · PMID 21465247
  42. The effect of induced alkalosis and submaximal cycling on neuromuscular response during sustained isometric contractionJ Sports Sci · PMID 19787544
  43. Effect of alkalosis on plasma epinephrine responses to high intensity cycle exercise in humansEur J Appl Physiol · PMID 12012079
  44. Effect of induced alkalosis on the power-duration relationship of "all-out" exerciseMed Sci Sports Exerc · PMID 19952817
  45. The effects of serial and acute NaHCO3 loading in well-trained cyclistsJ Strength Cond Res · PMID 23001395
  46. Effects of induced metabolic alkalosis on prolonged intermittent-sprint performanceMed Sci Sports Exerc · PMID 15870629
  47. Dose-related effects of prolonged NaHCO3 ingestion during high-intensity exerciseMed Sci Sports Exerc · PMID 17019296
  48. Effects of caffeine, sodium bicarbonate, and their combined ingestion on high-intensity cycling performanceInt J Sport Nutr Exerc Metab · PMID 22693238
  49. Sodium bicarbonate ingestion does not improve performance in women cyclistsMed Sci Sports Exerc · PMID 7869886
  50. Multiday acute sodium bicarbonate intake improves endurance capacity and reduces acidosis in menJ Int Soc Sports Nutr · PMID 23531361
  51. Effect of sodium bicarbonate ingestion upon repeated sprintsBr J Sports Med · PMID 2730998
  52. Effect of sodium bicarbonate contribution on energy metabolism during exercise: a systematic review and meta-analysis.J Int Soc Sports Nutr · PMID 33546730
  53. Sodium bicarbonate can be used as an ergogenic aid in high-intensity, competitive cycle ergometry of 1 h durationEur J Appl Physiol Occup Physiol · PMID 10367725
  54. Reliability and effect of sodium bicarbonate: buffering and 2000-m rowing performanceInt J Sports Physiol Perform · PMID 22634964
  55. Influence of sodium bicarbonate on performance and hydration in lightweight rowingInt J Sports Physiol Perform · PMID 21941012
  56. The effect of induced alkalosis and acidosis on plasma lactate and work output in elite oarsmenEur J Appl Physiol Occup Physiol · PMID 2548862
  57. Bicarbonate attenuates arterial desaturation during maximal exercise in humansJ Appl Physiol · PMID 12133884
  58. Plasma pH does not influence the cerebral metabolic ratio during maximal whole body exerciseJ Physiol · PMID 21098003
  59. Does sodium-bicarbonate ingestion improve simulated judo performanceInt J Sport Nutr Exerc Metab · PMID 17507744
  60. Effects of Sodium Bicarbonate Supplementation on Muscular Strength and Endurance: A Systematic Review and Meta-analysis.Sports Med · PMID 32096113
  61. Sodium bicarbonated mineral water decreases postprandial lipaemia in postmenopausal women compared to a low mineral waterBr J Nutr · PMID 16197584
  62. Efficacy of baking soda-containing chewing gum in removing natural tooth stainCompend Contin Educ Dent · PMID 11913307
  63. Effects of a Baking Soda Gum on extrinsic dental stain: results of a longitudinal 4-week assessmentCompend Contin Educ Dent · PMID 11913306
  64. A clinical investigation to evaluate reduction in dental stain provided by the once-daily use of a breath mint or chewing gumCompend Contin Educ Dent · PMID 11913308
  65. Sodium bicarbonate ingestion and boxing performanceJ Strength Cond Res · PMID 19625976
  66. Acute and chronic effect of sodium bicarbonate ingestion on Wingate test performance: a systematic review and meta-analysisJ Sports Sci · PMID 30319077
  67. Effects of Sodium Bicarbonate Ingestion on Measures of Wingate Test Performance: A Meta-AnalysisJ Am Nutr Assoc · PMID 33314967
  68. Pre-exercise alkalosis and acid-base recoveryInt J Sports Med · PMID 18004683
  69. Sodium bicarbonate supplementation prevents skilled tennis performance decline after a simulated matchJ Int Soc Sports Nutr · PMID 20977701