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Dr. Grey AI

Supplement

Red Yeast Rice

Red yeast rice is rice fermented with a yeast that makes monacolin K, a natural form of lovastatin that slows an enzyme the liver uses to build cholesterol. Most people look at it for high cholesterol, where the evidence is strong, and in trials of people with type 2 diabetes, LDL cholesterol fell. Apolipoprotein A showed no clear difference, though that evidence is very limited.

Sources: PMID 35111069; PMID 26246836

Best evidence
Grade A
Conditions studied
2
Outcomes
10
Graded outcomes
1101

Evidence by condition

  • Strong
  • Moderate
  • Limited
  • Very limited

2 conditions

Type 2 Diabetes: outcomes studied for Red Yeast Rice
GradeOutcomeEffectSizeStudiesPeopleStudies list
Low-density lipoprotein (LDL)

Moderate Improvement

Improves (the measure goes down)Moderate effect2 studies891 people
High-density lipoprotein (HDL)

Moderate Improvement

Improves (the measure goes up)Moderate effect891 people
Total cholesterolImproves (the measure goes down)891 people
TriglyceridesImproves (the measure goes down)891 people
Dyslipidemia: outcomes studied for Red Yeast Rice
GradeOutcomeEffectSizeStudiesPeopleStudies list
Apolipoprotein A

No effect

NoneNo effect1,012 people
Low-density lipoprotein (LDL)Improves (the measure goes down)2 studies1,012 people
Apolipoprotein BImproves (the measure goes down)1,012 people
High-density lipoprotein (HDL)Improves (the measure goes up)1,012 people
Total cholesterolImproves (the measure goes down)1,012 people
TriglyceridesImproves (the measure goes down)1,012 people

Key findings

  • Low-density lipoprotein (LDL)Type 2 DiabetesImproves (the measure goes down)
  • High-density lipoprotein (HDL)Type 2 DiabetesImproves (the measure goes up)
  • Apolipoprotein ADyslipidemia

Shop the evidence-backed picks

Third-party tested Red Yeast Rice products, in the forms the graded studies used where we can match them.

  • Grade A

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Studies cited

2 studies from PubMed

  1. Red Yeast Rice for Hyperlipidemia: A Meta-Analysis of 15 High-Quality Randomized Controlled Trials.Front Pharmacol · PMID 35111069
  2. Xuezhikang Capsule for Type 2 Diabetes with Hyperlipemia: A Systematic Review and Meta-Analysis of Randomized Clinical Trails.Evid Based Complement Alternat Med · PMID 26246836