Supplement
Perilla is a leafy plant in the mint family whose seeds yield an oil rich in alpha-linolenic acid, a plant omega-3 fat the body uses for cell membranes. In people with high cholesterol, one trial found that C-reactive protein, a marker of inflammation, went down and HDL, the so-called good cholesterol, improved. That trial included only 36 people, so the evidence is limited.
- Updated
- How we grade
- 1 study cited
- Best evidence
- Grade C
- Conditions studied
- 3
- Outcomes
- 23
- Graded outcomes
- 0040
Evidence by condition
- Strong
- Moderate
- Limited
- Very limited
| Grade | Outcome | Effect | Size | Studies | People | Studies list |
|---|---|---|---|---|---|---|
| C-Reactive Protein (CRP) Moderate Decrease | Improves (the measure goes down) | Moderate effect | 36 people | |||
| High-density lipoprotein (HDL) Small Improvement | Improves (the measure goes up) | Small effect | 36 people | |||
| Low-density lipoprotein (LDL) | Improves (the measure goes down) | 1 study | 36 people | |||
Studies that measured low-density lipoprotein (ldl) | ||||||
| Liver Enzymes | Changes; see studies | 36 people | ||||
| Plasminogen Inhibitor-1 | Improves (the measure goes up) | 36 people | ||||
| TNF-Alpha | Improves (the measure goes down) | 36 people | ||||
| Total cholesterol | Improves (the measure goes down) | 36 people | ||||
| Triglycerides | Improves (the measure goes down) | 36 people | ||||
General Cardiovascular Health
| Grade | Outcome | Effect | Size | Studies | People | Studies list |
|---|---|---|---|---|---|---|
| C-Reactive Protein (CRP) Moderate Decrease | Improves (the measure goes down) | Moderate effect | 36 people | |||
| Low-density lipoprotein (LDL) | Improves (the measure goes down) | 1 study | 36 people | |||
Studies that measured low-density lipoprotein (ldl) | ||||||
| High-density lipoprotein (HDL) | Improves (the measure goes up) | 36 people | ||||
| Liver Enzymes | Changes; see studies | 36 people | ||||
| Plasminogen Inhibitor-1 | Improves (the measure goes up) | 36 people | ||||
| TNF-Alpha | Improves (the measure goes down) | 36 people | ||||
| Total cholesterol | Improves (the measure goes down) | 36 people | ||||
| Triglycerides | Improves (the measure goes down) | 36 people | ||||
| Grade | Outcome | Effect | Size | Studies | People | Studies list |
|---|---|---|---|---|---|---|
| C-Reactive Protein (CRP) Moderate Decrease | Improves (the measure goes down) | Moderate effect | 36 people | |||
| Low-density lipoprotein (LDL) | Improves (the measure goes down) | 1 study | 36 people | |||
Studies that measured low-density lipoprotein (ldl) | ||||||
| High-density lipoprotein (HDL) | Improves (the measure goes up) | 36 people | ||||
| Liver Enzymes | Changes; see studies | 36 people | ||||
| Plasminogen Inhibitor-1 | Improves (the measure goes up) | 36 people | ||||
| TNF-Alpha | Improves (the measure goes down) | 36 people | ||||
| Triglycerides | Improves (the measure goes down) | 36 people | ||||
Key findings
- C-Reactive Protein (CRP)Improves (the measure goes down)
- High-density lipoprotein (HDL)Improves (the measure goes up)
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- Grade C
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Studies cited
1 study from PubMed