Supplement
DMAE (dimethylaminoethanol) is a compound related to choline, a nutrient the body uses to build the messenger chemical acetylcholine, which nerve cells rely on for memory and learning. People mostly look at it for cognitive decline, and a single trial of 241 people with suspected early Alzheimer's disease found no clear difference after six months. The evidence is very limited, since that one study tested a particular DMAE-based formulation, so it says little about DMAE on its own.
Sources: PMID 22330824
- Updated
- How we grade
- 1 study cited
- Best evidence
- Grade D
- Conditions studied
- 2
- Outcomes
- 2
- Graded outcomes
- 0001
Evidence by condition
- Strong
- Moderate
- Limited
- Very limited
Alzheimer’s Disease
| Grade | Outcome | Effect | Size | Studies | People | Studies list |
|---|---|---|---|---|---|---|
| Cognitive Decline No effect | NoneNo effect | 1 study | 241 people | |||
Studies that measured cognitive decline | ||||||
| Grade | Outcome | Effect | Size | Studies | People | Studies list |
|---|---|---|---|---|---|---|
| Cognitive Decline | Changes; see studies | 1 study | 241 people | |||
Studies that measured cognitive decline | ||||||
Key findings
- Cognitive Decline
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- Grade D
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Studies cited
1 study from PubMed