Chlorogenic Acid

Chlorogenic acid is found in coffee mostly and a lot of plant compounds; it holds promise in many aspects of health and cognition similar to bioflavonoids and shares some effects similar to caffeine but less potent. May decrease the absorption of dietary carbohydrate.

Quick Answer

What it is

Chlorogenic acid is found in coffee mostly and a lot of plant compounds; it holds promise in many aspects of health and cognition similar to bioflavonoids and shares some effects similar to caffeine but less potent. May decrease the absorption of dietary carbohydrate.

Key findings

  • Grade C: Subjective Well-Being (Cognitive Improvement)
  • Grade C: Blood Pressure (High Blood Pressure)
  • Grade C: Blood glucose (Obesity)

Safety

No specific caution or interaction language was detected in the current summary/outcome notes.

ℹ️ Quick Facts: Chlorogenic Acid

Quick Facts: Chlorogenic Acid

  • Best Evidence:Grade C
  • Conditions Studied:5
  • Research Outcomes:11
  • Key Effect:Cognitive Improvement
Outcomes by grade:
A0
B0
C4
D2
5 conditions · 11 outcomes

Detailed Outcomes

Grade:
Effect:
Size:
Sort:
|
C
Subjective Well-Being
Small Improvement
smallImproves
D
Cognition
No effect
none
C
Blood Pressure
Moderate Improvement
moderateImproves
?
Weight
Improves
C
Blood glucose
Small Improvement
1 study
smallImproves
?
Insulin
Worsens
C
Glycemic Control
Small Improvement
1 study
smallImproves
?
Weight
Improves
D
Cognition
No effect
none
?
Subjective Well-Being
Improves
?
Homocysteine
Improves

Related Supplements

Saffron

6 shared conditions · 390 outcomes

Saffron is a spice with antioxidant properties derived from the flowering plant Crocus sativus. When used as a supplement, saffron seems to be effective at reducing symptoms of depression and possibly anxiety.

Panax Ginseng (Korean Ginseng)

6 shared conditions · 228 outcomes

Panax ginseng is commonly referred to as “Korean ginseng”. It appears to be effective for mood, immunity, and cognition, but is subpar for erectile function, testosterone, and exercise performance.

Green Tea Extract

6 shared conditions · 110 outcomes

Green tea extract is obtained from green tea leaves and contains high levels of flavonoids, catechins like EGCG, and often caffeine. It might reduce oxidative stress biomarkers and cardiovascular disease risk factors and improve cognitive function. However, the quality of evidence is low to moderate, and high doses can cause liver damage.

Fish Oil

6 shared conditions · 448 outcomes

Fish oil is a mix of mostly EPA and DHA derived from fatty fish. It reduces triglycerides, but does not seem to affect the rate of cardiovascular events. It appears to reduce the symptoms of depression and improve some painful, inflammatory conditions.

Curcumin

6 shared conditions · 502 outcomes

Curcumin is the primary bioactive substance in turmeric. It has anti-inflammatory properties and can alleviate symptoms of depression as well as improve pain and function in people with osteoarthritis.

Cocoa Extract

6 shared conditions · 269 outcomes

Cocoa, a powder that is rich in polyphenols, is used to make chocolate. Cocoa products can have effects like lowering blood pressure and inflammation and have resulted in small improvements to some outcomes in cardiovascular disease.

Vitamin D

5 shared conditions · 308 outcomes

Vitamin D is a fat-soluble vitamin that our skin synthesizes when exposed to the sun. It benefits us in many ways, from bone health to mood.

Vitamin C

5 shared conditions · 262 outcomes

Vitamin C, or ascorbic acid, is an essential vitamin and a very popular supplement due to its antioxidant properties, safety profile, and low price. Many people supplement with vitamin C because it is believed to reduce symptoms of the common cold.