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Dr. Grey AI

Supplement

Chitosan

Chitosan is a fibre made from the shells of shellfish that binds to fats and bile acids in the gut, which is why it is sold as a weight and cholesterol aid. People mostly look at it for weight loss, and meta-analyses found they lost about 1.7 to 2 kilograms more than those on placebo over several weeks, though the evidence is limited. That difference was statistically significant but clinically modest, and cholesterol showed a similarly small drop in the studies reviewed.

Best evidence
Grade C
Conditions studied
2
Outcomes
2
Graded outcomes
0020

Evidence by condition

  • Strong
  • Moderate
  • Limited
  • Very limited

2 conditions

Obesity: outcomes studied for Chitosan
GradeOutcomeEffectSizeStudiesPeopleStudies list
Body Weight

Meta-analyses: Weight loss of 1.7-2kg more than placebo over 4-24 weeks. Effect is statistically significant but clinically modest.

Improves (the measure goes down)Small effect1,200 people
High Cholesterol: outcomes studied for Chitosan
GradeOutcomeEffectSizeStudiesPeopleStudies list
Total Cholesterol

Meta-analysis: Modest reduction in total cholesterol (5-8%) and LDL. Mechanism via bile acid binding.

Improves (the measure goes down)Small effect800 people

Key findings

  • Body WeightObesityImproves (the measure goes down)
  • Total CholesterolHigh CholesterolImproves (the measure goes down)

Shop Chitosan

Third-party tested Chitosan products. The evidence above is limited, so read it before you buy.

  • Grade C

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