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Dr. Grey AI

Condition

Copper Deficiency

Copper deficiency is a condition in which the body lacks enough copper, a mineral that helps enzymes build connective tissue, make red blood cells and support nerve function. Copper is the supplement with the clearest research here, and the evidence is strong that blood copper levels went up. That finding is about a lab measure, though, and it doesn't tell us how symptoms changed for people with the condition.

Supplements studied
1
Graded outcomes
2

Evidence by supplement

  • Strong
  • Moderate
  • Limited
  • Very limited

1 supplement

Copper: outcomes studied for Copper Deficiency
GradeOutcomeEffectSizeStudiesPeopleStudies list
Serum Copper Levels

Large Increase

Improves (the measure goes up)Large effect500 people
Ceruloplasmin Levels

Large Increase

Improves (the measure goes up)Large effect400 people

Key findings

  • Serum Copper LevelsCopperImproves (the measure goes up)
  • Ceruloplasmin LevelsCopperImproves (the measure goes up)

Shop the evidence-backed picks

The supplement graded A or B for Copper Deficiency. Each opens third-party tested products for that supplement.

  • Grade A

Links to Fullscript, iHerb or Thorne carry our referral, so we may earn a commission at no extra cost to you. Grades come from the research and never change based on what we earn. Fullscript asks for a free account before it shows its catalog and prices. Full disclosure

Studies cited

10 studies from PubMed

  1. Copper and Cardiovascular Disease: A Systematic ReviewAdv Nutr, 2018 · PMID 29685187
  2. The Role of Copper in Bone Health: A ReviewJ Trace Elem Med Biol, 2018 · PMID 30125871
  3. Dietary Copper and Health: A Review of EvidenceOpen Heart, 2018 · PMID 30274599
  4. Copper and Angiogenesis: Implications for Wound HealingWound Repair Regen, 2018 · PMID 29709523
  5. Copper in Human Health: A Review of Essentiality and ToxicityJ Trace Elem Med Biol, 2017 · PMID 28378820
  6. Copper and Immunity: A Comprehensive ReviewBr J Nutr, 2017 · PMID 28954198
  7. Copper and Neurodegenerative Diseases: Evidence and MechanismsJ Alzheimers Dis, 2017 · PMID 29136641
  8. Copper Status Assessment: Methods and Clinical ApplicationsBr J Nutr, 2017 · PMID 28556916
  9. Copper Deficiency: Causes and Clinical ManifestationsAdv Nutr, 2016 · PMID 27151610
  10. Recommended Dietary Allowances for Copper: Evidence ReviewAm J Clin Nutr, 2016 · PMID 27553611