Tea Tree Oil

Tea tree oil is an essential oil from the Australian Melaleuca alternifolia tree with potent antimicrobial properties. Evidence supports topical use for acne (C-grade, comparable to benzoyl peroxide but slower), nail fungus, and athlete's foot. Active components include terpinen-4-ol and other terpenes. TOPICAL USE ONLY - oral ingestion is toxic and can cause CNS depression, ataxia, and coma. May cause contact dermatitis in sensitive individuals. Effective at 5-15% concentration for most applications.

Quick Answer

What it is

Tea tree oil is an essential oil from the Australian Melaleuca alternifolia tree with potent antimicrobial properties. Evidence supports topical use for acne (C-grade, comparable to benzoyl peroxide but slower), nail fungus, and athlete's foot.

Key findings

  • Grade C: Acne Lesions (Acne)
  • Grade C: Fungal Cure
  • Grade C: Clinical Cure

Safety

No specific caution or interaction language was detected in the current summary/outcome notes.

โ„น๏ธ Quick Facts: Tea Tree Oil

Quick Facts: Tea Tree Oil

  • Best Evidence:Grade C
  • Conditions Studied:1
  • Research Outcomes:5
  • Key Effect:Acne
Outcomes by grade:
A0
B0
C4
D1
1 conditions ยท 5 outcomes

Detailed Outcomes

|
C
Acne Lesions
5% tea tree oil similar efficacy to 5% benzoyl peroxide but slower onset (fewer side effects)
3 studies
moderateโ†“Worsens
C
Fungal Cure
100% tea tree oil comparable to clotrimazole for appearance; lower mycological cure rate
2 studies
moderateโ†‘Improves
C
Clinical Cure
25-50% tea tree oil effective for symptomatic relief; lower mycological cure than antifungals
2 studies
moderateโ†‘Improves
C
Lice Eradication
Tea tree + lavender oil combination effective for lice
1 study
moderateโ†‘Improves
D
Gingivitis/Plaque
Gel formulations show modest effect; mouthwash limited evidence
2 studies
smallโ†‘Worsens

Evidence by Condition

Best grade per condition (each condition may have multiple outcomes)

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