PQQ

PQQ is a small molecule once thought to be a vitamin, although its actions in the human body are not related to this hypothesized vitamin-like mechanism. Via its actions as a REDOX agent in cells, it can modify signalling and is thought to support mitochondrial function.

Quick Answer

What it is

PQQ is a small molecule once thought to be a vitamin, although its actions in the human body are not related to this hypothesized vitamin-like mechanism. Via its actions as a REDOX agent in cells, it can modify signalling and is thought to support mitochondrial function.

Key findings

  • Grade C: Fatigue Symptoms (Fatigue)
  • Grade C: Pain (Fatigue)
  • Grade D: Blood glucose (Metabolic Health)

Safety

No specific caution or interaction language was detected in the current summary/outcome notes.

ℹ️ Quick Facts: PQQ

Quick Facts: PQQ

  • Best Evidence:Grade C
  • Conditions Studied:4
  • Research Outcomes:21
  • Key Effect:Fatigue
Outcomes by grade:
A0
B0
C4
D1
4 conditions Β· 21 outcomes

Detailed Outcomes

|
C
Fatigue Symptoms
Small Improvement
1 study
small↓Improves
C
Pain
Small Improvement
1 study
small↓Improves
?
Sleep Quality
1 study
↑Improves
?
Stress Signs and Symptoms
1 study
↓Improves
C
Fatigue Symptoms
Small Improvement
1 study
small↓Improves
?
Pain
1 study
↓Improves
?
Sleep Quality
1 study
↑Improves
?
Stress Signs and Symptoms
1 study
↓Improves
C
Fatigue Symptoms
Small Improvement
1 study
small↓Improves
?
Pain
1 study
↓Improves
?
Sleep Quality
1 study
↑Improves
?
Stress Signs and Symptoms
1 study
↓Improves
D
Blood glucose
No effect
none
?
C-Reactive Protein (CRP)
1 study
↓Improves
?
High-density lipoprotein (HDL)
1 study
↑Improves
?
Interleukin 6
1 study
↓Improves
?
Liver Enzymes
1 study
↑Worsens
?
Low-density lipoprotein (LDL)
1 study
↓Improves
?
Oxidative Stress Biomarkers
1 study
↓Improves
?
TMAO
1 study
↑Improves
?
Triglycerides
1 study
↓Improves

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