Pelargonidin
Pelargonidin is one of six anthocyanidins (anthocyanin aglycones) responsible for red/orange coloring in plants, particularly strawberries. It is the simplest anthocyanidin structurally. NO GRADED OUTCOMES - very limited human research. Better to obtain through strawberry/berry consumption than as an isolated supplement. Has antioxidant and potential neuroprotective properties in preclinical research. Bioavailability may be enhanced by other flavonoids like quercetin.
Quick Answer
What it is
Pelargonidin is one of six anthocyanidins (anthocyanin aglycones) responsible for red/orange coloring in plants, particularly strawberries. It is the simplest anthocyanidin structurally.
Key findings
- Grade C: Alzheimer's Disease Neuropathology
- Grade D: Neuroprotection
- Grade D: Antioxidant Status
Safety
- A community-based epidemiological study of 575 deceased participants (Rush Memory and Aging Project) found that higher pelargonidin intake was associated with reduced amyloid-beta accumulation and fewer phosphorylated tau tangles in brain tissue, particularly among those without APOE e4 risk factor.
- One month of daily dosing produced no detectable adverse effects.
ℹ️ Quick Facts: Pelargonidin
Quick Facts: Pelargonidin
- Best Evidence:Grade C
- Conditions Studied:2
- Research Outcomes:6
- Key Effect:Alzheimer’s Disease
Detailed Outcomes
Evidence by Condition
Best grade per condition (each condition may have multiple outcomes)
Research Citations (6)
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