Supplement
Microlactin is a milk-derived protein preparation made from the milk of hyperimmunized cows, and it is thought to influence inflammation-related signaling in the body. People mostly look at it for osteoarthritis, and one small trial of 31 people found their joint symptoms improved. The evidence is limited, since that is a single short study, and the small trials on cholesterol and blood pressure were too tiny to draw firm conclusions.
Sources: PMID 11985942
- Updated
- How we grade
- 3 studies cited
- Best evidence
- Grade C
- Conditions studied
- 3
- Outcomes
- 12
- Graded outcomes
- 0031
Evidence by condition
- Strong
- Moderate
- Limited
- Very limited
| Grade | Outcome | Effect | Size | Studies | People | Studies list |
|---|---|---|---|---|---|---|
| Osteoarthritis Symptoms Small Improvement | Improves (the measure goes down) | Small effect | 1 study | 31 people | ||
Studies that measured osteoarthritis symptoms | ||||||
| Pain | Improves (the measure goes down) | 31 people | ||||
| Grade | Outcome | Effect | Size | Studies | People | Studies list |
|---|---|---|---|---|---|---|
| Blood Pressure Small Improvement | Improves (the measure goes down) | Small effect | 30 people | |||
| High-density lipoprotein (HDL) No effect | NoneNo effect | 30 people | ||||
| Total cholesterol | Improves (the measure goes down) | 1 study | 41 people | |||
Studies that measured total cholesterol | ||||||
| Triglycerides | Improves (the measure goes down) | 1 study | 30 people | |||
Studies that measured triglycerides | ||||||
| Low-density lipoprotein (LDL) | Improves (the measure goes down) | 30 people | ||||
| Grade | Outcome | Effect | Size | Studies | People | Studies list |
|---|---|---|---|---|---|---|
| Blood Pressure Small Improvement | Improves (the measure goes down) | Small effect | 30 people | |||
| Total cholesterol | Improves (the measure goes down) | 1 study | 30 people | |||
Studies that measured total cholesterol | ||||||
| Triglycerides | Improves (the measure goes down) | 1 study | 30 people | |||
Studies that measured triglycerides | ||||||
| High-density lipoprotein (HDL) | Improves (the measure goes up) | 30 people | ||||
| Low-density lipoprotein (LDL) | Improves (the measure goes down) | 30 people | ||||
Key findings
- Osteoarthritis SymptomsImproves (the measure goes down)
- Blood PressureImproves (the measure goes down)
- High-density lipoprotein (HDL)
Shop Microlactin
Third-party tested Microlactin products. The evidence above is limited, so read it before you buy.
- Grade C
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Studies cited
3 studies from PubMed
- Cholesterol-lowering and blood pressure effects of immune milk
- Cholesterol-lowering effect of skim milk from immunized cows in hypercholesterolemic patients
- Effects of a milk-based bioactive micronutrient beverage on pain symptoms and activity of adults with osteoarthritis: a double-blind, placebo-controlled clinical evaluation