Lactase Enzyme

If you can't digest the lactose in dairy (Lactose intolerance), you can either supplement with lactase enzyme pills or consume dairy that's predigested with the lactase enzyme.

Quick Answer

What it is

If you can't digest the lactose in dairy (Lactose intolerance), you can either supplement with lactase enzyme pills or consume dairy that's predigested with the lactase enzyme.

Key findings

  • Grade A: Bloating (Lactose Intolerance)
  • Grade B: Abdominal Pain (Lactose Intolerance)
  • Grade N/A: Breath Hydrogen (Lactose Intolerance)

Safety

No specific caution or interaction language was detected in the current summary/outcome notes.

ℹ️ Quick Facts: Lactase Enzyme

Quick Facts: Lactase Enzyme

  • Best Evidence:Grade A
  • Conditions Studied:2
  • Research Outcomes:11
  • Grade A Findings:1
  • Grade B Findings:1
  • Key Effect:Lactose Intolerance
Outcomes by grade:
A1
B1
C0
D0
2 conditions · 11 outcomes

Detailed Outcomes

A
Bloating
Moderate Improvement
3 studies
moderateImproves
B
Abdominal Pain
Small Improvement
3 studies
smallImproves
?
Breath Hydrogen
Improves
?
Flatulence
Worsens
?
Lactose Intolerance Symptoms
4 studies
Improves
?
Diarrhea Symptoms
3 studies
Improves
?
Headaches
2 studies
Improves
?
Heartburn Symptoms
1 study
Improves
?
Nausea Symptoms
1 study
Improves
?
Stool Consistency
1 study
Improves
?
Glycemic Control
Improves

Evidence by Condition

Best grade per condition (each condition may have multiple outcomes)

Research Citations (11)

A combination of acid lactase from Aspergillus oryzae and yogurt bacteria improves lactose digestion in lactose maldigesters synergistically: A randomized, controlled, double-blind cross-over trial
PMID: 25042846
The effect of oral supplementation with Lactobacillus reuteri or tilactase in lactose intolerant patients: randomized trial
PMID: 20391953
Enzyme replacement therapy for primary adult lactase deficiency. Effective reduction of lactose malabsorption and milk intolerance by direct addition of beta-galactosidase to milk at mealtime
PMID: 6434367
Long-term acceptance of low-lactose milk
PMID: 114042
Effective reduction of lactose maldigestion in preschool children by direct addition of beta-galactosidases to milk at mealtime
PMID: 3106927
Effects of exogenous lactase administration on hydrogen breath excretion and intestinal symptoms in patients presenting lactose malabsorption and intolerance
PMID: 24967391
Dietary manipulation of postprandial colonic lactose fermentation: II. Addition of exogenous, microbial beta-galactosidases at mealtime
PMID: 3918430
Effect of exogenous beta-galactosidase in patients with lactose malabsorption and intolerance: a crossover double-blind placebo-controlled study
PMID: 15674309
beta-Galactosidase from Aspergillus niger in adult lactose malabsorption: a double-blind crossover study
PMID: 1543816
Beta-galactosidase tablets in the treatment of lactose intolerance in pediatrics
PMID: 2122719

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