Kokilaksha

Asteracantha longifolia (Kokilaksha or Talmakhana) is an Ayurvedic herb traditionally used as an aphrodisiac, hepatoprotective agent, and for glucose disturbances. NO GRADED OUTCOMES - research is extremely preliminary with only animal and in vitro studies. May enhance glycogen synthesis and protect against lipid peroxidation (potency comparable to vitamin E in one study). Also traditionally used as a diuretic. The plant components are not well characterized and toxicology data is lacking. Cannot recommend use due to insufficient evidence on both efficacy and safety.

Quick Answer

What it is

Key findings

Grade D: Liver Protection
Grade D: Glycogen Synthesis
Grade D: Antioxidant Status

Safety

No specific caution or interaction language was detected in the current summary/outcome notes.

ℹ️ Quick Facts: Kokilaksha

Quick Facts: Kokilaksha

Best Evidence:Grade D
Conditions Studied:1
Research Outcomes:4
Key Effect:Antioxidant Status

Outcomes by grade:

1 conditions · 4 outcomes

Detailed Outcomes

Liver Protection

In animal studies, Asteracantha longifolia extracts demonstrated hepatoprotective effects, reducing markers of liver damage. No human trials have been conducted to validate these findings.

2 studies

small↑Improves

Glycogen Synthesis

In rodent models, Kokilaksha extracts enhanced glycogen synthesis. This effect has not been studied in humans and the mechanism is not well characterized.

1 study

small↑Improves

Sexual Function

Kokilaksha has a traditional Ayurvedic reputation as an aphrodisiac, with some animal studies exploring this claim. There is no scientific validation of aphrodisiac effects in human subjects.

1 study

small↑Improves

Antioxidant Status

In one preclinical study, Asteracantha longifolia demonstrated antioxidant effects and protection against lipid peroxidation with potency reported as comparable to vitamin E. No human data exists to confirm this effect.

1 study

small↑Improves

Evidence by Condition

Best grade per condition (each condition may have multiple outcomes)

DAntioxidant Status

1 outcome · 1 study

↑Antioxidant StatusImproves

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