Carnosine

Carnosine, a protein made up of the amino acids beta-alanine and L-histidine, is present in high amounts in the brain, the heart, the gastrointestinal tract, and skeletal muscle. Supplementing with carnosine is often used to improve muscle strength and exercise performance.

Quick Answer

What it is

Carnosine, a protein made up of the amino acids beta-alanine and L-histidine, is present in high amounts in the brain, the heart, the gastrointestinal tract, and skeletal muscle. Supplementing with carnosine is often used to improve muscle strength and exercise performance.

Key findings

  • Grade B: Blood glucose (Type 2 Diabetes)
  • Grade B: Beta-cell function (Type 2 Diabetes)
  • Grade N/A: High-density lipoprotein (HDL) (Type 2 Diabetes)

Safety

No specific caution or interaction language was detected in the current summary/outcome notes.

ℹ️ Quick Facts: Carnosine

Quick Facts: Carnosine

  • Best Evidence:Grade B
  • Conditions Studied:2
  • Research Outcomes:20
  • Grade B Findings:3
  • Key Effect:Type 2 Diabetes
Outcomes by grade:
A0
B3
C0
D0
2 conditions · 20 outcomes

Detailed Outcomes

B
Blood glucose
Small Improvement
small↓Improves
B
Beta-cell function
Small Increase
3 studies
small↑Improves
?
High-density lipoprotein (HDL)
6 studies
↑Improves
?
Total cholesterol
6 studies
↓Improves
?
Insulin
4 studies
↑Worsens
?
Low-density lipoprotein (LDL)
4 studies
↓Improves
?
Insulin Resistance
3 studies
↓Improves
?
Body Fat
↓Improves
?
Bone Mineral Density
1 study
↑Improves
?
Muscle Strength
1 study
↑Improves
B
Beta-cell function
Small Increase
3 studies
small↑Improves
?
Blood glucose
↓Improves
?
High-density lipoprotein (HDL)
6 studies
↑Improves
?
Total cholesterol
6 studies
↓Improves
?
Insulin
4 studies
↑Worsens
?
Low-density lipoprotein (LDL)
4 studies
↓Improves
?
Insulin Resistance
3 studies
↓Improves
?
Body Fat
↓Improves
?
Bone Mineral Density
1 study
↑Improves
?
Muscle Strength
1 study
↑Improves

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