Arachidonic Acid

Arachidonic acid (AA) is the primary omega-6 fatty acid relevant to the omega-3:6 ratio discussion. It's a precursor to inflammatory eicosanoids (prostaglandins, leukotrienes) but also involved in muscle signaling. C-grade evidence for small anaerobic capacity improvement. D-grade for body fat (no effect). Used in bodybuilding for muscle building, though the inflammatory signaling is a double-edged sword. CONTRAINDICATED in inflammatory conditions like rheumatoid arthritis and IBD.

Quick Answer

What it is

Arachidonic acid (AA) is the primary omega-6 fatty acid relevant to the omega-3:6 ratio discussion. It's a precursor to inflammatory eicosanoids (prostaglandins, leukotrienes) but also involved in muscle signaling.

Key findings

  • Grade C: Anaerobic Capacity (Body Composition)
  • Grade D: Body Fat (Body Composition)
  • Grade N/A: Cortisol (Body Composition)

Safety

No specific caution or interaction language was detected in the current summary/outcome notes.

ℹ️ Quick Facts: Arachidonic Acid

Quick Facts: Arachidonic Acid

  • Best Evidence:Grade C
  • Conditions Studied:4
  • Research Outcomes:20
  • Key Effect:Body Composition
Outcomes by grade:
A0
B0
C5
D1
4 conditions Β· 20 outcomes

Detailed Outcomes

|
C
Anaerobic Capacity
Small Improvement
1 study
small↑Improves
D
Body Fat
No effect
1 study
none
?
Cortisol
1 study
↑Worsens
?
Muscle Mass
1 study
↑Improves
?
Power Output
↑Improves
?
Testosterone
1 study
↑Improves
C
Anaerobic Capacity
Small Improvement
1 study
small↑Improves
C
Anaerobic Capacity
Small Improvement
1 study
small↑Improves
C
Anaerobic Capacity
Small Improvement
1 study
small↑Improves
?
Body Fat
1 study
↑Worsens
?
Cortisol
1 study
↑Worsens
?
Muscle Mass
1 study
↑Improves
?
Power Output
↑Improves
?
Testosterone
1 study
↑Improves
C
Anaerobic Capacity
Small Improvement
1 study
small↑Improves
?
Body Fat
1 study
↑Worsens
?
Cortisol
1 study
↑Worsens
?
Muscle Mass
1 study
↑Improves
?
Power Output
↑Improves
?
Testosterone
1 study
↑Improves

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