Anatabine

Anatabine is a minor tobacco alkaloid also found in nightshade vegetables (eggplant, peppers). Marketed for anti-inflammatory properties via STAT3/NF-kB inhibition. IMPORTANT: Current supplement doses are 6-12x LOWER than doses showing effects in studies. D-grade evidence across all outcomes (no effects on blood pressure, heart rate). Was marketed in 'Anatabloc' supplement. Research doses require 68-110mg but supplements typically contain only 6mg. Essentially, commercially available products are likely underdosed.

Quick Answer

What it is

Anatabine is a minor tobacco alkaloid also found in nightshade vegetables (eggplant, peppers). Marketed for anti-inflammatory properties via STAT3/NF-kB inhibition.

Key findings

  • Grade D: Blood Pressure
  • Grade D: Heart Rate
  • Grade N/A: Muscle Damage (General Athletic Performance)

Safety

No specific caution or interaction language was detected in the current summary/outcome notes.

ℹ️ Quick Facts: Anatabine

Quick Facts: Anatabine

  • Best Evidence:Grade D
  • Conditions Studied:3
  • Research Outcomes:17
  • Key Effect:Muscle Recovery
Outcomes by grade:
A0
B0
C0
D5
3 conditions · 17 outcomes

Detailed Outcomes

|
D
Blood Pressure
No effect
1 study
none
D
Heart Rate
No effect
none
D
Blood Pressure
No effect
1 study
none
?
Heart Rate
Worsens
?
Muscle Damage
1 study
Worsens
?
Muscle Soreness
1 study
Worsens
?
Power Output
1 study
Improves
D
Blood Pressure
No effect
1 study
none
?
Heart Rate
Worsens
?
Muscle Damage
1 study
Worsens
?
Muscle Soreness
1 study
Worsens
?
Power Output
1 study
Improves
D
Blood Pressure
No effect
1 study
none
?
Heart Rate
Worsens
?
Muscle Damage
1 study
Worsens
?
Muscle Soreness
1 study
Worsens
?
Power Output
1 study
Improves

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