Protocol · Skin Health
Cellulite Support Protocol
Collagen Peptides and Gotu Kola (Centella asiatica) are the core of this stack, with 7 supporting supplements. Each row gives the amount the protocol lists and the grade our evidence database holds for that supplement in Cellulite Support.
We are re-verifying the studies cited on protocol pages; only confirmed citations are shown.
The stack
9 supplements · none graded yet · 1 confirmed study
| Grade | Supplement | Amount listed | Why it’s in the stack | Evidence on file | Shop |
|---|---|---|---|---|---|
| Primary stackThe core of this protocol | |||||
| Collagen Peptides | Amount listed: 2.5–10 g daily | Supports skin structure and elasticity; studies show improvement in cellulite appearance with daily supplementation | Not graded yet | ||
Confirmed studies for Collagen Peptides (titles as PubMed lists them) | |||||
| Gotu Kola (Centella asiatica) | Amount listed: 60–120 mg triterpenes (or 600–1,200 mg standardized extract) daily | Supports collagen synthesis and microcirculation; traditional use for connective tissue; studied for cellulite | Not graded yet | ||
| Supporting stackListed as additions to the core | |||||
| Vitamin C | Amount listed: 500–1,000 mg daily | Essential for collagen synthesis; antioxidant that supports skin health | Not graded yet | ||
| Horse Chestnut | Amount listed: 300–600 mg standardized extract (50 mg escin) daily | Supports vascular health and reduces fluid retention; may improve microcirculation in cellulite-affected areas | Not graded yet | ||
| Omega-3 Fatty Acids | Amount listed: 1–2 g EPA+DHA daily | Anti-inflammatory; supports healthy skin cell membranes | Not graded yet | ||
| Grape Seed Extract | Amount listed: 100–300 mg daily | Proanthocyanidins support connective tissue and microcirculation; antioxidant | Not graded yet | ||
| Green Tea Extract | Amount listed: 270–400 mg EGCG daily | Catechins support thermogenesis and may help with fat metabolism; antioxidant for skin | Not graded yet | ||
| Caffeine | Amount listed: 100–200 mg orally; topical creams applied directly | Topical caffeine improves blood flow and may temporarily reduce cellulite appearance; oral form supports thermogenesis | Not graded yet | ||
| Retinol (Vitamin A) | Amount listed: Topical 0.1–0.3% retinol cream applied to affected areas | Topical retinol may thicken skin and improve appearance; supports skin cell turnover | Not graded yet | ||
Shop the evidence-backed picks
The collection holds the supplements we grade A or B for its theme, in third-party tested products where the catalog has them. It opens in our Fullscript store. You can look through it without signing in; Fullscript asks for a free account to order.
Or shop one supplement
Each opens third-party tested products, matched to the dose above where we can.
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How this protocol works
In plain language
Cellulite is a common, harmless skin condition that causes lumpy, dimpled flesh on the thighs, hips, buttocks, and abdomen. It affects 80-90% of women after puberty and is much less common in men. Cellulite occurs when fat cells push up against the skin while fibrous bands (septa) pull down, creating the dimpled appearance.
IMPORTANT: Cellulite is not a medical condition or disease. It's a normal variation in how fat is distributed and structured beneath the skin. No treatment is required unless desired for cosmetic reasons.
FACTORS THAT INFLUENCE CELLULITE:
- Genetics (biggest factor - determines skin structure and fat distribution)
- Hormones (estrogen plays a role)
- Body composition (more fat = more visible cellulite)
- Skin thickness (thin skin shows cellulite more)
- Age (skin loses elasticity over time)
LIFESTYLE APPROACHES:
- Regular exercise (improves muscle tone and circulation)
- Healthy diet (maintaining healthy weight)
- Hydration
- Dry brushing (may temporarily improve appearance)
- Massage (increases circulation)
Collagen Peptides* have the best evidence for cellulite. A double-blind study showed significant improvement in skin waviness after 6 months of daily supplementation.
Gotu Kola (Centella asiatica)* has been used traditionally for connective tissue and has some evidence for improving skin texture.
Vitamin C* is essential for collagen production.
Caffeine* (topical) temporarily improves circulation and may reduce appearance.
Expected timeline: Supplements take 3-6 months to show visible improvement. No supplement completely eliminates cellulite. Medical procedures (laser, radiofrequency) may provide more dramatic results.