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Dr. Grey AI

Condition

Spinal Cord Injury

A spinal cord injury is damage to the nerves running through the spine, which causes paralysis and loss of sensation below the injury and can affect bones, bowel, bladder, circulation and skin. Vitamin D and calcium are the supplements most often looked at, mainly for the rapid bone loss that follows injury. Little research on them in this condition has been reviewed here so far, so no trial findings can be reported yet.

Supplements studied
1
Graded outcomes
0
Trials
1
People studied
24

Evidence by supplement

  • Strong
  • Moderate
  • Limited
  • Very limited

1 supplement

Cannabidiol (CBD)

Cannabidiol (CBD): outcomes studied for Spinal Cord Injury
GradeOutcomeEffectSizeStudiesPeopleStudies list
PainImproves (the measure goes down)3 studies24 people

Studies that measured pain

The Spinal Cord Injury Long-Term Health Support protocol

2 primary supplements · 7 supporting supplements

  • Vitamin D2,000–4,000 IU daily (often higher doses needed; monitor levels)
  • Calcium1,000–1,200 mg daily (from diet + supplements)

See the full protocol

Studies cited

17 studies from PubMed

  1. Effects of Cannabidiol and Delta-9-Tetrahydrocannabinol on Emotion, Cognition, and Attention: A Double-Blind, Placebo-Controlled, Randomized Experimental Trial in Healthy VolunteersFront Psychiatry · PMID 33304282
  2. Cannabidiol presents an inverted U-shaped dose-response curve in a simulated public speaking testBraz J Psychiatry · PMID 30328956
  3. The effects of cannabidiol on persecutory ideation and anxiety in a high trait paranoid groupJ Psychopharmacol · PMID 29086614
  4. Cannabidiol (CBD) as an Adjunctive Therapy in Schizophrenia: A Multicenter Randomized Controlled TrialAm J Psychiatry · PMID 29241357
  5. The effects of cannabidiol (CBD) on cognition and symptoms in outpatients with chronic schizophrenia a randomized placebo controlled trialPsychopharmacology · PMID 29619533
  6. Low-Dose Cannabidiol Is Safe but Not Effective in the Treatment for Crohn's Disease, a Randomized Controlled TrialDig Dis Sci · PMID 28349233
  7. Inverted U-Shaped Dose-Response Curve of the Anxiolytic Effect of Cannabidiol during Public Speaking in Real LifeFront Pharmacol · PMID 28553229
  8. Action of cannabidiol on the anxiety and other effects produced by delta 9-THC in normal subjectsPsychopharmacology · PMID 6285406
  9. Effects of ipsapirone and cannabidiol on human experimental anxietyJ Psychopharmacol · PMID 22290374
  10. A Randomized, Double-blind, Placebo-controlled, Parallel-group, Pilot Study of Cannabidiol-rich Botanical Extract in the Symptomatic Treatment of Ulcerative ColitisInflamm Bowel Dis · PMID 29538683
  11. Effect of Cannabidiol on Drop Seizures in the Lennox-Gastaut SyndromeN Engl J Med · PMID 29768152
  12. Cannabidiol in patients with treatment-resistant epilepsy: an open-label interventional trialLancet Neurol · PMID 26724101
  13. Cannabidiol as a new treatment for drug-resistant epilepsy in tuberous sclerosis complexEpilepsia · PMID 27696387
  14. The efficacy of cannabidiol for seizures reduction in pharmacoresistant epilepsy: a systematic review and meta-analysis.Acta Epileptol · PMID 40217555
  15. Chronic Pain Treatment With Cannabidiol in Kidney Transplant Patients in UruguayTransplant Proc · PMID 29579828
  16. Short-Term Efficacy of CBD-Enriched Hemp Oil in Girls with Dysautonomic Syndrome after Human Papillomavirus VaccinationIsr Med Assoc J · PMID 28457055
  17. A preliminary controlled study to determine whether whole-plant cannabis extracts can improve intractable neurogenic symptomsClin Rehabil · PMID 12617376

Supplement stack for Spinal Cord Injury