Theanine, also commonly referred to as L-theanine, is a naturally occurring amino acid found in tea. Supplementation with L-theanine may help reduce stress and anxiety and might improve sleep quality and some aspects of cognitive function.

Saffron

1 shared condition · 390 outcomes

Saffron is a spice with antioxidant properties derived from the flowering plant Crocus sativus. When used as a supplement, saffron seems to be effective at reducing symptoms of depression and possibly anxiety.

Resveratrol

1 shared condition · 318 outcomes

Resveratrol is a bioactive molecule found in plant sources such as grapes, peanuts, blueberries, and, famously, red wine. Resveratrol has anti-inflammatory and antioxidant properties that benefit cardiovascular function, glycemic control, and lipid metabolism. Although it’s promoted for lifespan extension, there’s no evidence for this in humans and limited evidence in animals.

Probiotics

1 shared condition · 215 outcomes

Probiotics are microorganisms that can have a positive effect on health.

Panax Ginseng (Korean Ginseng)

1 shared condition · 228 outcomes

Panax ginseng is commonly referred to as “Korean ginseng”. It appears to be effective for mood, immunity, and cognition, but is subpar for erectile function, testosterone, and exercise performance.

Omega-3 Fatty Acids

1 shared condition · 60 outcomes

Omega-3 fatty acids are polyunsaturated fatty acids, distinguished by having a double bond three carbons away from the end of the hydrocarbon tail. Examples of omega-3s are alpha-linolenic acid (ALA), Eicosapentaenoic Acid (EPA), and docosahexaenoic acid (DHA). This page covers evidence for omega-3s as a whole and is under construction. For mixed EPA and DHA, see fish oil.

N-Acetylcysteine

1 shared condition · 72 outcomes

NAC is a precursor to L-cysteine and glutathione (master antioxidant). PROVEN life-saving for acetaminophen overdose. B-grade evidence for respiratory conditions (bronchitis, COPD) and blood glucose in PCOS. Widely studied for psychiatric conditions (OCD, addiction, depression) but evidence is mixed. Acts as mucolytic, antioxidant, and glutathione precursor. FDA controversially questioned its supplement status in 2020 but enforcement relaxed. Generally safe but may have pro-oxidant effects at very high doses. One of the most researched nutraceuticals.