Supplement
Rhamnus nakaharai is a plant in the buckthorn genus, used in Taiwanese folk medicine, that contains quercetin glycosides, which are plant antioxidants. People have traditionally used it for constipation, but no clinical studies have tested it for that, so the evidence is very limited. Its relative cascara has known laxative effects, and quercetin has shown anti-inflammatory effects in lab work, but those findings come from other species or isolated compounds, not this plant.
- Updated
- How we grade
- Best evidence
- Grade D
- Conditions studied
- 2
- Outcomes
- 3
- Graded outcomes
- 0003
Evidence by condition
- Strong
- Moderate
- Limited
- Very limited
General
| Grade | Outcome | Effect | Size | Studies | People | Studies list |
|---|---|---|---|---|---|---|
| Constipation Relief No published clinical or preclinical studies exist for Rhamnus nakaharai specifically. Traditional Taiwanese folk medicine use for constipation has been reported, and other Rhamnus species (e.g., R. purshiana/cascara) contain anthraquinones with known laxative effects, but no direct evidence supports this species. | Improves (the measure goes up) | Small effect |
| Grade | Outcome | Effect | Size | Studies | People | Studies list |
|---|---|---|---|---|---|---|
| Asthma Symptoms No published studies exist on Rhamnus nakaharai for asthma. Traditional Taiwanese folk use for asthma has been reported. Quercetin, a constituent of the plant, has shown anti-inflammatory and bronchodilatory effects in preclinical models, but these findings come from isolated quercetin research, not from this species. | Improves (the measure goes down) | Small effect |
| Grade | Outcome | Effect | Size | Studies | People | Studies list |
|---|---|---|---|---|---|---|
| Antioxidant Status No published studies have assessed the antioxidant effects of Rhamnus nakaharai. The plant contains quercetin glycosides, which are well-characterized antioxidants in other contexts, but no direct evidence from this species exists. Superior quercetin sources with actual research data are available. | Improves (the measure goes up) | Small effect |
Key findings
- Constipation ReliefImproves (the measure goes up)
- Asthma SymptomsImproves (the measure goes down)
- Antioxidant StatusImproves (the measure goes up)
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- Grade D
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