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Propolis

Propolis is a resin bees make from plant sap and wax to seal their hives, and it has antiviral and antimicrobial properties. People mostly look at it for cold sores, but the evidence there is limited, and little research has shown clear results so far. The best-supported finding lies elsewhere: a review of over 1,000 adults found blood glucose improved, while blood pressure and body fat showed no clear difference.

Sources: PMID 39097520

Best evidence
Grade B
Conditions studied
3
Outcomes
13
Graded outcomes
0102

Evidence by condition

  • Strong
  • Moderate
  • Limited
  • Very limited

3 conditions

Metabolic Health: outcomes studied for Propolis
GradeOutcomeEffectSizeStudiesPeopleStudies list
Blood glucose

Small Improvement

Improves (the measure goes down)Small effect1 study1,072 people
HbA1cImproves (the measure goes down)1,072 people
InsulinChanges; see studies1,072 people
Insulin ResistanceImproves (the measure goes down)1,072 people
Liver EnzymesChanges; see studies1,072 people
Body Composition: outcomes studied for Propolis
GradeOutcomeEffectSizeStudiesPeopleStudies list
Blood Pressure

No effect

NoneNo effect1,082 people
Body Fat

No effect

NoneNo effect1,082 people
WeightImproves (the measure goes down)1 study1,082 people
Body Mass Index (BMI)Improves (the measure goes down)1,082 people
Hip CircumferenceImproves (the measure goes down)1,082 people
Waist circumferenceImproves (the measure goes down)1,082 people
Waist-Hip RatioImproves (the measure goes up)1,082 people

Cold Sores: outcomes studied for Propolis
GradeOutcomeEffectSizeStudiesPeopleStudies list
Cold Sore Symptom DurationImproves (the measure goes up)1 study839 people

Key findings

  • Blood glucoseMetabolic HealthImproves (the measure goes down)
  • Blood PressureBody Composition
  • Body FatBody Composition

Shop the evidence-backed picks

Third-party tested Propolis products, in the forms the graded studies used where we can match them.

  • Grade B

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Studies cited

3 studies from PubMed

  1. Effects of Propolis Consumption on Glycemic Indices and Liver Enzymes in Adults: A Grading of Recommendations Assessment, Development, and valuation-assessed Systematic Review and Dose-Response Meta-analysis.Clin Ther · PMID 39097520
  2. The Effects of Propolis Consumption on Body Composition and Blood Pressure: A Systematic Review and Dose-Response Meta-Analysis.Curr Ther Res Clin Exp · PMID 39247130
  3. Effect of honey and propolis, compared to acyclovir, against Herpes Simplex Virus (HSV)-induced lesions: A systematic review and meta-analysis.J Ethnopharmacol · PMID 34965458